John Kuriyan
John Kuriyan
Professor of Molecular and Cell Biology and Chemistry
Verified email at - Homepage
Cited by
Cited by
Crystallographic R factor refinement by molecular dynamics
AT Brünger, J Kuriyan, M Karplus
Science 235 (4787), 458-460, 1987
Structural mechanism for STI-571 inhibition of abelson tyrosine kinase
T Schindler, W Bornmann, P Pellicena, WT Miller, B Clarkson, J Kuriyan
Science 289 (5486), 1938-1942, 2000
The conformational plasticity of protein kinases
M Huse, J Kuriyan
Cell 109 (3), 275-282, 2002
Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia
NP Shah, JM Nicoll, B Nagar, ME Gorre, RL Paquette, J Kuriyan, ...
Cancer cell 2 (2), 117-125, 2002
An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor
X Zhang, J Gureasko, K Shen, PA Cole, J Kuriyan
Cell 125 (6), 1137-1149, 2006
Crystal structure of the Src family tyrosine kinase Hck
F Sicheri, I Moarefi, J Kuriyan
Nature 385 (6617), 602-609, 1997
Molecular dynamics and protein function
M Karplus, J Kuriyan
Proceedings of the National Academy of Sciences 102 (19), 6679-6685, 2005
Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571)
B Nagar, WG Bornmann, P Pellicena, T Schindler, DR Veach, WT Miller, ...
Cancer research 62 (15), 4236-4243, 2002
Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA
TSR Krishna, XP Kong, S Gary, PM Burgers, J Kuriyan
Cell 79 (7), 1233-1243, 1994
Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1
J Goldberg, H Huang, Y Kwon, P Greengard, AC Nairn, J Kuriyan
Nature 376 (6543), 745-753, 1995
Structural basis for the autoinhibition of c-Abl tyrosine kinase
B Nagar, O Hantschel, MA Young, K Scheffzek, D Veach, W Bornmann, ...
Cell 112 (6), 859-871, 2003
The structural basis of the activation of Ras by Sos
PA Boriack-Sjodin, SM Margarit, D Bar-Sagi, J Kuriyan
Nature 394 (6691), 337-343, 1998
Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin α
E Conti, M Uy, L Leighton, G Blobel, J Kuriyan
Cell 94 (2), 193-204, 1998
Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms
G Waksman, SE Shoelson, N Pant, D Cowburn, J Kuriyan
Cell 72 (5), 779-790, 1993
Structure of the C-terminal region of p21WAF1/CIP1 complexed with human PCNA
JM Gulbis, Z Kelman, J Hurwitz, M O'Donnell, J Kuriyan
Cell 87 (2), 297-306, 1996
Three-dimensional structure of the β subunit of E. coli DNA polymerase III holoenzyme: a sliding DNA clamp
XP Kong, R Onrust, M O'Donnell, J Kuriyan
Cell 69 (3), 425-437, 1992
Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA
X Chen, U Vinkemeier, Y Zhao, D Jeruzalmi, JE Darnell, J Kuriyan
Cell 93 (5), 827-839, 1998
Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides
G Waksman, D Kominos, SC Robertson, N Pant, D Baltimore, RB Birge, ...
Nature 358 (6388), 646-653, 1992
Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia
CC Smith, Q Wang, CS Chin, S Salerno, LE Damon, MJ Levis, AE Perl, ...
Nature 485 (7397), 260-263, 2012
Activation of the Sire-family tyrosine kinase Hck by SH3 domain displacement
I Moarefi, M LaFevre-Bernt, F Sicheri, M Huse, CH Lee, J Kuriyan, ...
Nature 385 (6617), 650-653, 1997
The system can't perform the operation now. Try again later.
Articles 1–20