| The allosteric regulation of pyruvate kinase by fructose-1, 6-bisphosphate MS Jurica, A Mesecar, PJ Heath, W Shi, T Nowak, BL Stoddard Structure 6 (2), 195-210, 1998 | 524 | 1998 |
| Transition State Structure of Purine Nucleoside Phosphorylase and Principles of Atomic Motion in Enzymatic Catalysis, A Fedorov, W Shi, G Kicska, E Fedorov, PC Tyler, RH Furneaux, ... Biochemistry 40 (4), 853-860, 2001 | 240 | 2001 |
| Structure of murine CTLA-4 and its role in modulating T cell responsiveness DA Ostrov, W Shi, JCD Schwartz, SC Almo, SG Nathenson Science 290 (5492), 816-819, 2000 | 211 | 2000 |
| The 2.0 Å structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor W Shi, CM Li, PC Tyler, RH Furneaux, C Grubmeyer, VL Schramm, ... nature structural biology 6 (6), 588-593, 1999 | 210 | 1999 |
| Metallomics and metalloproteomics W Shi, MR Chance Cellular and Molecular Life Sciences 65, 3040-3048, 2008 | 187 | 2008 |
| Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function W Shi, LM Ting, GA Kicska, A Lewandowicz, PC Tyler, GB Evans, ... Journal of Biological Chemistry 279 (18), 18103-18106, 2004 | 178 | 2004 |
| The 2.0 Å Structure of Malarial Purine Phosphoribosyltransferase in Complex with a Transition-State Analogue Inhibitor, W Shi, CM Li, PC Tyler, RH Furneaux, SM Cahill, ME Girvin, C Grubmeyer, ... Biochemistry 38 (31), 9872-9880, 1999 | 177 | 1999 |
| Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor J Yang, Z Liu, C Wang, R Yang, JK Rathkey, OW Pinkard, W Shi, Y Chen, ... Proceedings of the National Academy of Sciences 115 (26), 6792-6797, 2018 | 161 | 2018 |
| Nucleoside hydrolase from Leishmania major: cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-Å crystal structure W Shi, VL Schramm, SC Almo Journal of Biological Chemistry 274 (30), 21114-21120, 1999 | 150 | 1999 |
| Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins LM Ting, W Shi, A Lewandowicz, V Singh, A Mwakingwe, MR Birck, ... Journal of Biological Chemistry 280 (10), 9547-9554, 2005 | 149 | 2005 |
| Structure of the actin crosslinking core of fimbrin MG Klein, W Shi, U Ramagopal, Y Tseng, D Wirtz, DR Kovar, CJ Staiger, ... Structure 12 (6), 999-1013, 2004 | 135 | 2004 |
| The Structure of l-Aspartate Ammonia-Lyase from Escherichia coli, W Shi, J Dunbar, MMK Jayasekera, RE Viola, GK Farber Biochemistry 36 (30), 9136-9144, 1997 | 114 | 1997 |
| Metalloproteomics: forward and reverse approaches in metalloprotein structural and functional characterization W Shi, MR Chance Current opinion in chemical biology 15 (1), 144-148, 2011 | 109 | 2011 |
| Metalloproteomics: high-throughput structural and functional annotation of proteins in structural genomics W Shi, C Zhan, A Ignatov, BA Manjasetty, N Marinkovic, M Sullivan, ... Structure 13 (10), 1473-1486, 2005 | 103 | 2005 |
| Four generations of transition-state analogues for human purine nucleoside phosphorylase MC Ho, W Shi, A Rinaldo-Matthis, PC Tyler, GB Evans, K Clinch, SC Almo, ... Proceedings of the National Academy of Sciences 107 (11), 4805-4812, 2010 | 96 | 2010 |
| Picomolar transition state analogue inhibitors of human 5 ‘-methylthioadenosine phosphorylase and X-ray structure with MT-Immucillin-A V Singh, W Shi, GB Evans, PC Tyler, RH Furneaux, SC Almo, ... Biochemistry 43 (1), 9-18, 2004 | 91 | 2004 |
| Structure and Inhibition of a Quorum Sensing Target from Streptococcus pneumoniae V Singh, W Shi, SC Almo, GB Evans, RH Furneaux, PC Tyler, GF Painter, ... Biochemistry 45 (43), 12929-12941, 2006 | 90 | 2006 |
| Atomic motion in enzymatic reaction coordinates VL Schramm, W Shi Current opinion in structural biology 11 (6), 657-665, 2001 | 88 | 2001 |
| Catalytic mechanism of a retinoid isomerase essential for vertebrate vision PD Kiser, J Zhang, M Badiee, Q Li, W Shi, X Sui, M Golczak, GP Tochtrop, ... Nature chemical biology 11 (6), 409-415, 2015 | 85 | 2015 |
| Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase GA Kicska, PC Tyler, GB Evans, RH Furneaux, W Shi, A Fedorov, ... Biochemistry 41 (49), 14489-14498, 2002 | 81 | 2002 |
