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Wuxian Shi
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The allosteric regulation of pyruvate kinase by fructose-1, 6-bisphosphate
MS Jurica, A Mesecar, PJ Heath, W Shi, T Nowak, BL Stoddard
Structure 6 (2), 195-210, 1998
5151998
Transition State Structure of Purine Nucleoside Phosphorylase and Principles of Atomic Motion in Enzymatic Catalysis,
A Fedorov, W Shi, G Kicska, E Fedorov, PC Tyler, RH Furneaux, ...
Biochemistry 40 (4), 853-860, 2001
2412001
Structure of murine CTLA-4 and its role in modulating T cell responsiveness
DA Ostrov, W Shi, JCD Schwartz, SC Almo, SG Nathenson
Science 290 (5492), 816-819, 2000
2092000
The 2.0 structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor
W Shi, CM Li, PC Tyler, RH Furneaux, C Grubmeyer, VL Schramm, ...
Nature structural biology 6 (6), 588-593, 1999
2051999
Metallomics and metalloproteomics
W Shi, MR Chance
Cellular and Molecular Life Sciences 65, 3040-3048, 2008
1842008
Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function
W Shi, LM Ting, GA Kicska, A Lewandowicz, PC Tyler, GB Evans, ...
Journal of Biological Chemistry 279 (18), 18103-18106, 2004
1772004
The 2.0 Structure of Malarial Purine Phosphoribosyltransferase in Complex with a Transition-State Analogue Inhibitor,
W Shi, CM Li, PC Tyler, RH Furneaux, SM Cahill, ME Girvin, C Grubmeyer, ...
Biochemistry 38 (31), 9872-9880, 1999
1741999
Nucleoside hydrolase from Leishmania major: cloning, expression, catalytic properties, transition state inhibitors, and the 2.5- crystal structure
W Shi, VL Schramm, SC Almo
Journal of Biological Chemistry 274 (30), 21114-21120, 1999
1501999
Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins
LM Ting, W Shi, A Lewandowicz, V Singh, A Mwakingwe, MR Birck, ...
Journal of Biological Chemistry 280 (10), 9547-9554, 2005
1492005
Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor
J Yang, Z Liu, C Wang, R Yang, JK Rathkey, OW Pinkard, W Shi, Y Chen, ...
Proceedings of the National Academy of Sciences 115 (26), 6792-6797, 2018
1482018
Structure of the actin crosslinking core of fimbrin
MG Klein, W Shi, U Ramagopal, Y Tseng, D Wirtz, DR Kovar, CJ Staiger, ...
Structure 12 (6), 999-1013, 2004
1352004
The Structure of l-Aspartate Ammonia-Lyase from Escherichia coli,
W Shi, J Dunbar, MMK Jayasekera, RE Viola, GK Farber
Biochemistry 36 (30), 9136-9144, 1997
1131997
Metalloproteomics: forward and reverse approaches in metalloprotein structural and functional characterization
W Shi, MR Chance
Current opinion in chemical biology 15 (1), 144-148, 2011
1062011
Metalloproteomics: high-throughput structural and functional annotation of proteins in structural genomics
W Shi, C Zhan, A Ignatov, BA Manjasetty, N Marinkovic, M Sullivan, ...
Structure 13 (10), 1473-1486, 2005
1002005
Four generations of transition-state analogues for human purine nucleoside phosphorylase
MC Ho, W Shi, A Rinaldo-Matthis, PC Tyler, GB Evans, K Clinch, SC Almo, ...
Proceedings of the National Academy of Sciences 107 (11), 4805-4812, 2010
932010
Picomolar transition state analogue inhibitors of human 5 ‘-methylthioadenosine phosphorylase and X-ray structure with MT-Immucillin-A
V Singh, W Shi, GB Evans, PC Tyler, RH Furneaux, SC Almo, ...
Biochemistry 43 (1), 9-18, 2004
902004
Structure and Inhibition of a Quorum Sensing Target from Streptococcus pneumoniae
V Singh, W Shi, SC Almo, GB Evans, RH Furneaux, PC Tyler, GF Painter, ...
Biochemistry 45 (43), 12929-12941, 2006
892006
Atomic motion in enzymatic reaction coordinates
VL Schramm, W Shi
Current opinion in structural biology 11 (6), 657-665, 2001
862001
Catalytic mechanism of a retinoid isomerase essential for vertebrate vision
PD Kiser, J Zhang, M Badiee, Q Li, W Shi, X Sui, M Golczak, GP Tochtrop, ...
Nature chemical biology 11 (6), 409-415, 2015
822015
Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase
GA Kicska, PC Tyler, GB Evans, RH Furneaux, W Shi, A Fedorov, ...
Biochemistry 41 (49), 14489-14498, 2002
802002
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Articles 1–20