Philip Anton van der Merwe
Philip Anton van der Merwe
Professor of Molecular Immunology, University of Oxford
Verified email at - Homepage
Cited by
Cited by
The leucocyte antigen factsbook
AN Barclay, MH Brown, SKAKA Law, AJ McKnight, MG Tomlinson, ...
Elsevier, 1997
The interaction properties of costimulatory molecules revisited
AV Collins, DW Brodie, RJC Gilbert, A Iaboni, R Manso-Sancho, B Walse, ...
Immunity 17 (2), 201-210, 2002
A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts
ML Dustin, MW Olszowy, AD Holdorf, J Li, S Bromley, N Desai, P Widder, ...
Cell 94 (5), 667-677, 1998
Production of soluble αβ T‐cell receptor heterodimers suitable for biophysical analysis of ligand binding
BE Willcox, GF Gao, JR Wyer, CA O'callaghan, BK Jakobsen, JM Boulter, ...
Protein Science 8 (11), 2418-2423, 1999
CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics
PA van der Merwe, DL Bodian, S Daenke, P Linsley, SJ Davis
The Journal of experimental medicine 185 (3), 393-404, 1997
Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G
M Shiroishi, K Tsumoto, K Amano, Y Shirakihara, M Colonna, VM Braud, ...
Proceedings of the National Academy of Sciences 100 (15), 8856-8861, 2003
Molecular interactions mediating T cell antigen recognition
PA van der Merwe, SJ Davis
Annual review of immunology 21 (1), 659-684, 2003
The kinetic-segregation model: TCR triggering and beyond
SJ Davis, PA Van Der Merwe
Nature immunology 7 (8), 803-809, 2006
Mechanisms for T cell receptor triggering
PA Van Der Merwe, O Dushek
Nature Reviews Immunology 11 (1), 47-55, 2011
2B4, the natural killer and T cell immunoglobulin superfamily surface protein, is a ligand for CD48
MH Brown, K Boles, P Anton Van der Merwe, V Kumar, PA Mathew, ...
The Journal of experimental medicine 188 (11), 2083-2090, 1998
The structure and ligand interactions of CD2: implications for T-cell function
SJ Davis, PA Van Der Merwe
Immunology today 17 (4), 177-187, 1996
T-cell receptor triggering is critically dependent on the dimensions of its peptide-MHC ligand
K Choudhuri, D Wiseman, MH Brown, K Gould, PA van der Merwe
Nature 436 (7050), 578-582, 2005
TCR binding to peptide-MHC stabilizes a flexible recognition interface
BE Willcox, GF Gao, JR Wyer, JE Ladbury, JI Bell, BK Jakobsen, ...
Immunity 10 (3), 357-365, 1999
Survival of FimH-expressing enterobacteria in macrophages relies on glycolipid traffic
DM Baorto, Z Gao, R Malaviya, ML Dustin, A van der Merwe, DM Lublin, ...
Nature 389 (6651), 636-639, 1997
Structural and kinetic basis for heightened immunogenicity of T cell vaccines
JL Chen, G Stewart-Jones, G Bossi, NM Lissin, L Wooldridge, EML Choi, ...
The Journal of experimental medicine 201 (8), 1243-1255, 2005
The nature of molecular recognition by T cells
SJ Davis, S Ikemizu, EJ Evans, L Fugger, TR Bakker, PA van der Merwe
Nature immunology 4 (3), 217-224, 2003
The mast cell tumor necrosis factor α response to FimH-expressing Escherichia coli is mediated by the glycosylphosphatidylinositol-anchored molecule CD48
R Malaviya, Z Gao, K Thankavel, PA van der Merwe, SN Abraham
Proceedings of the National Academy of Sciences 96 (14), 8110-8115, 1999
Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics
MI Barton, SA MacGowan, MA Kutuzov, O Dushek, GJ Barton, ...
Elife 10, e70658, 2021
CDR3 loop flexibility contributes to the degeneracy of TCR recognition
JB Reiser, C Darnault, C Grégoire, T Mosser, G Mazza, A Kearney, ...
Nature immunology 4 (3), 241-247, 2003
Siglecs: a family of sialic-acid binding lectins
PR Crocker, EA Clark, M Filbin, S Gordon, Y Jones, JH Kehrl, S Kelm, ...
Glycobiology 8 (2), v-vi, 1998
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