Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1 K Nosol, K Romane, RN Irobalieva, A Alam, J Kowal, N Fujita, KP Locher Proceedings of the National Academy of Sciences 117 (42), 26245-26253, 2020 | 201 | 2020 |
Structure and drug resistance of the Plasmodium falciparum transporter PfCRT J Kim, YZ Tan, KJ Wicht, SK Erramilli, SK Dhingra, J Okombo, J Vendome, ... Nature 576 (7786), 315-320, 2019 | 189 | 2019 |
Structure and mechanism of the ER-based glucosyltransferase ALG6 JS Bloch, G Pesciullesi, J Boilevin, K Nosol, RN Irobalieva, T Darbre, ... Nature 579 (7799), 443-447, 2020 | 68 | 2020 |
Discovery and characterization of potent dual P-glycoprotein and CYP3A4 inhibitors: design, synthesis, cryo-EM analysis, and biological evaluations S Urgaonkar, K Nosol, AM Said, NN Nasief, Y Bu, KP Locher, JYN Lau, ... Journal of Medicinal Chemistry 65 (1), 191-216, 2021 | 51 | 2021 |
Structure of human drug transporters OATP1B1 and OATP1B3 AD Ciută, K Nosol, J Kowal, S Mukherjee, AS Ramírez, B Stieger, ... Nature Communications 14 (1), 5774, 2023 | 38 | 2023 |
Structures of ABCB4 provide insight into phosphatidylcholine translocation K Nosol, R Bang-Sørensen, RN Irobalieva, SK Erramilli, B Stieger, ... Proceedings of the National Academy of Sciences 118 (33), e2106702118, 2021 | 33 | 2021 |
Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver H Liu, RN Irobalieva, R Bang-Sørensen, K Nosol, S Mukherjee, P Agrawal, ... Cell research 32 (8), 773-776, 2022 | 32 | 2022 |
Structural basis of lipopolysaccharide maturation by the O-antigen ligase KU Ashraf, R Nygaard, ON Vickery, SK Erramilli, CM Herrera, ... Nature 604 (7905), 371-376, 2022 | 31 | 2022 |
Antiviral HIV-1 SERINC restriction factors disrupt virus membrane asymmetry SA Leonhardt, MD Purdy, JR Grover, Z Yang, S Poulos, WE McIntire, ... Nature Communications 14 (1), 4368, 2023 | 14 | 2023 |
Structure of antiviral drug bulevirtide bound to hepatitis B and D virus receptor protein NTCP H Liu, D Zakrzewicz, K Nosol, RN Irobalieva, S Mukherjee, ... Nature Communications 15 (1), 2476, 2024 | 12 | 2024 |
Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP H Liu, RN Irobalieva, J Kowal, D Ni, K Nosol, R Bang-Sørensen, ... Nature Communications 14 (1), 7296, 2023 | 12 | 2023 |
Physicochemical properties and solubility of hydrochloride mucolytic agents A Pobudkowska, A Śliwińska, K Nosol Journal of Solution Chemistry 50 (5), 652-666, 2021 | 6 | 2021 |
CryoEM structures of the human HIV-1 restriction factor SERINC3 and function as a lipid transporter SA Leonhardt, MD Purdy, JR Grover, Z Yang, S Poulos, WE McIntire, ... bioRxiv, 2022.07. 06.498924, 2022 | 4 | 2022 |
Catalytic hydrogenation for a biomass-derived dicarboxylic acid valorisation with an ionic liquid and CO2 towards a perspective host guest building block molecule E Bogel-Łukasik, K Nosol, D Silva, CI Melo The Journal of Supercritical Fluids 133, 542-547, 2018 | 3 | 2018 |
Physicochemical properties and solubilities of drugs hydrochlorides in water and alcohols A Pobudkowska, A Szabłowska, K Nosal International Journal of Pharma Research & Review 5, 2016 | 2 | 2016 |
Production of Human ABC Transporters and Oligosaccharyltransferase Complexes for Structural Studies AS Ramírez, K Nosol, KP Locher Heterologous Expression of Membrane Proteins: Methods and Protocols, 273-294, 2022 | 1 | 2022 |
Structure of hepatitis B/D antiviral drug Bulevirtide bound to its receptor protein NTCP H Liu, D Zakrzewicz, K Nosol, RN Irobalieva, S Mukherjee, ... bioRxiv, 2024.01. 22.576510, 2024 | | 2024 |
Structural basis for CorA channel gating using conformation-specific synthetic antigen binders and single-particle cryo-EM SK Erramilli, PK Dominik, T Li, K Nosol, P Tokarz, P Dutka, M Zhao, ... Biophysical Journal 122 (3), 447a, 2023 | | 2023 |
Structural studies of human ABC transporters ABCB1 and ABCB4 K Nosol ETH Zurich, 2022 | | 2022 |
Visualizing Conformational Changes of the Magnesium Channel Cora using Synthetic Antibodies SK Erramilli, T Li, K Nosol, P Tokarz, P Dutka, PK Dominik, E Perozo, ... Biophysical Journal 118 (3), 273a, 2020 | | 2020 |