| The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer D Chakravarty, A Sboner, SS Nair, E Giannopoulou, R Li, S Hennig, ... Nature communications 5 (1), 5383, 2014 | 591 | 2014 |
| Modulators of protein–protein interactions LG Milroy, TN Grossmann, S Hennig, L Brunsveld, C Ottmann Chemical reviews 114 (9), 4695-4748, 2014 | 487 | 2014 |
| Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles S Hennig, G Kong, T Mannen, A Sadowska, S Kobelke, A Blythe, GJ Knott, ... Journal of Cell Biology 210 (4), 529-539, 2015 | 308 | 2015 |
| A novel photoreaction mechanism for the circadian blue light photoreceptor Drosophila cryptochrome A Berndt, T Kottke, H Breitkreuz, R Dvorsky, S Hennig, M Alexander, ... Journal of biological chemistry 282 (17), 13011-13021, 2007 | 236 | 2007 |
| Auto‐regulation of the circadian slave oscillator component AtGRP7 and regulation of its targets is impaired by a single RNA recognition motif point mutation JC Schöning, C Streitner, DR Page, S Hennig, K Uchida, E Wolf, ... The Plant Journal 52 (6), 1119-1130, 2007 | 147 | 2007 |
| Identification and Structure of Small‐Molecule Stabilizers of 14–3–3 Protein–Protein Interactions R Rose, S Erdmann, S Bovens, A Wolf, M Rose, S Hennig, H Waldmann, ... Angewandte Chemie International Edition 49 (24), 4129-4132, 2010 | 132 | 2010 |
| Crystal structure and interactions of the PAS repeat region of the Drosophila clock protein PERIOD Ö Yildiz, M Doi, I Yujnovsky, L Cardone, A Berndt, S Hennig, S Schulze, ... Molecular cell 17 (1), 69-82, 2005 | 132 | 2005 |
| RNA structure and cellular applications of fluorescent light‐up aptamers S Neubacher, S Hennig Angewandte Chemie International Edition 58 (5), 1266-1279, 2019 | 102 | 2019 |
| Structural and Functional Analyses of PAS Domain Interactions of the Clock Proteins Drosophila PERIOD and Mouse PERIOD2 S Hennig, HM Strauss, K Vanselow, Ö Yildiz, S Schulze, J Arens, ... PLoS biology 7 (4), e1000094, 2009 | 93 | 2009 |
| Unwinding the differences of the mammalian PERIOD clock proteins from crystal structure to cellular function N Kucera, I Schmalen, S Hennig, R Öllinger, HM Strauss, A Grudziecki, ... Proceedings of the National Academy of Sciences 109 (9), 3311-3316, 2012 | 77 | 2012 |
| Structure-based design of non-natural macrocyclic peptides that inhibit protein–protein interactions DM Krüger, A Glas, D Bier, N Pospiech, K Wallraven, L Dietrich, ... Journal of medicinal chemistry 60 (21), 8982-8988, 2017 | 51 | 2017 |
| Redox modulation of PTEN phosphatase activity by hydrogen peroxide and bisperoxidovanadium complexes CU Lee, G Hahne, J Hanske, T Bange, D Bier, C Rademacher, S Hennig, ... Angewandte Chemie International Edition 54 (46), 13796-13800, 2015 | 48 | 2015 |
| Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein–protein interactions P Thiel, L Röglin, N Meissner, S Hennig, O Kohlbacher, C Ottmann Chemical communications 49 (76), 8468-8470, 2013 | 48 | 2013 |
| In situ cyclization of native proteins: structure‐based design of a bicyclic enzyme M Pelay‐Gimeno, T Bange, S Hennig, TN Grossmann Angewandte Chemie International Edition 57 (35), 11164-11170, 2018 | 39 | 2018 |
| Bicyclic Β‐sheet mimetics that target the transcriptional coactivator Β‐catenin and inhibit Wnt signaling M Wendt, R Bellavita, A Gerber, NL Efrém, T van Ramshorst, NM Pearce, ... Angewandte Chemie International Edition 60 (25), 13937-13944, 2021 | 36 | 2021 |
| Adapting free energy perturbation simulations for large macrocyclic ligands: how to dissect contributions from direct binding and free ligand flexibility K Wallraven, FL Holmelin, A Glas, S Hennig, AI Frolov, TN Grossmann Chemical science 11 (8), 2269-2276, 2020 | 29 | 2020 |
| Constrained peptides with fine‐tuned flexibility inhibit NF‐Y transcription factor assembly S Jeganathan, M Wendt, S Kiehstaller, D Brancaccio, A Kuepper, ... Angewandte Chemie 131 (48), 17512-17519, 2019 | 24 | 2019 |
| Construct optimization for studying protein complexes: obtaining diffraction-quality crystals of the pseudosymmetric PSPC1–NONO heterodimer M Lee, DM Passon, S Hennig, AH Fox, CS Bond Acta Crystallographica Section D: Biological Crystallography 67 (11), 981-987, 2011 | 22 | 2011 |
| Identification of novel PANDAR protein interaction partners involved in splicing regulation N Pospiech, H Cibis, L Dietrich, F Müller, T Bange, S Hennig Scientific reports 8 (1), 2798, 2018 | 20 | 2018 |
| Using a specific RNA–protein interaction to quench the fluorescent RNA spinach L Roszyk, S Kollenda, S Hennig ACS chemical biology 12 (12), 2958-2964, 2017 | 13 | 2017 |
Tom N. GrossmannProfessor of Biomimetic Chemistry, Vrije Universiteit AmsterdamVerified email at vu.nl
