Max von Kleist
Max von Kleist
Robert Koch Institut
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Severe COVID-19 is marked by a dysregulated myeloid cell compartment
J Schulte-Schrepping, N Reusch, D Paclik, K Baßler, S Schlickeiser, ...
Cell 182 (6), 1419-1440. e23, 2020
Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and plasmablasts as hallmarks of severe COVID-19
JP Bernardes, N Mishra, F Tran, T Bahmer, L Best, JI Blase, D Bordoni, ...
Immunity 53 (6), 1296-1314. e9, 2020
Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19
B Krämer, R Knoll, L Bonaguro, M ToVinh, J Raabe, ...
Immunity 54 (11), 2650-2669. e14, 2021
Computational strategies to combat COVID-19: useful tools to accelerate SARS-CoV-2 and coronavirus research
F Hufsky, K Lamkiewicz, A Almeida, A Aouacheria, C Arighi, A Bateman, ...
Briefings in bioinformatics 22 (2), 642-663, 2021
Trends in respiratory virus circulation following COVID-19-targeted nonpharmaceutical interventions in Germany, January-September 2020: Analysis of national surveillance data
DY Oh, S Buda, B Biere, J Reiche, F Schlosser, S Duwe, M Wedde, ...
The Lancet Regional Health–Europe 6, 2021
Mutational interference mapping experiment (MIME) for studying RNA structure and function
RP Smyth, L Despons, G Huili, S Bernacchi, M Hijnen, J Mak, F Jossinet, ...
Nature methods 12 (9), 866-872, 2015
Pharmacokinetics and pharmacodynamics of the reverse transcriptase inhibitor tenofovir and prophylactic efficacy against HIV-1 infection
S Duwal, C Schütte, M von Kleist
PloS one 7 (7), e40382, 2012
Local c-di-GMP signaling in the control of synthesis of the E. coli biofilm exopolysaccharide pEtN-cellulose
AM Richter, A Possling, N Malysheva, KP Yousef, S Herbst, M von Kleist, ...
Journal of molecular biology 432 (16), 4576-4595, 2020
Drug-class specific impact of antivirals on the reproductive capacity of HIV
M von Kleist, S Menz, W Huisinga
PLoS computational biology 6 (3), e1000720, 2010
Serial synapse formation through filopodial competition for synaptic seeding factors
MN Özel, A Kulkarni, A Hasan, J Brummer, M Moldenhauer, IM Daumann, ...
Developmental cell 50 (4), 447-461. e8, 2019
HIV-1 polymerase inhibition by nucleoside analogs: cellular-and kinetic parameters of efficacy, susceptibility and resistance selection
M von Kleist, P Metzner, R Marquet, C Schütte
PLoS Computational Biology 8 (1), e1002359, 2012
Physiologically based pharmacokinetic modelling: a sub-compartmentalized model of tissue distribution
M von Kleist, W Huisinga
Journal of pharmacokinetics and pharmacodynamics 34, 789-806, 2007
HIV quasispecies dynamics during pro-active treatment switching: impact on multi-drug resistance and resistance archiving in latent reservoirs
M von Kleist, S Menz, H Stocker, K Arasteh, C Schütte, W Huisinga
PloS one 6 (3), e18204, 2011
Autophagy-dependent filopodial kinetics restrict synaptic partner choice during Drosophila brain wiring
FR Kiral, GA Linneweber, T Mathejczyk, SV Georgiev, MF Wernet, ...
Nature communications 11 (1), 1325, 2020
In cell mutational interference mapping experiment (in cell MIME) identifies the 5′ polyadenylation signal as a dual regulator of HIV-1 genomic RNA production and packaging
RP Smyth, MR Smith, AC Jousset, L Despons, G Laumond, T Decoville, ...
Nucleic acids research 46 (9), e57-e57, 2018
Analysis of long non-coding RNA and mRNA expression in bovine macrophages brings up novel aspects of Mycobacterium avium subspecies paratuberculosis infections
P Gupta, S Peter, M Jung, A Lewin, G Hemmrich-Stanisak, A Franke, ...
Scientific Reports 9 (1), 1571, 2019
Virus load kinetics and resistance development during oseltamivir treatment in infants and children infected with Influenza A (H1N1) 2009 and Influenza B viruses
B Rath, M von Kleist, F Tief, K Karsch, E Tuerk, S Muehlhans, F Louis, ...
The Pediatric infectious disease journal 31 (9), 899-905, 2012
Pharmacokinetic–pharmacodynamic relationship of NRTIs and its connection to viral escape: An example based on zidovudine
M von Kleist, W Huisinga
European journal of pharmaceutical sciences 36 (4-5), 532-543, 2009
Secondary data for global health digitalisation
AF Näher, CN Vorisek, SAI Klopfenstein, M Lehne, S Thun, S Alsalamah, ...
The Lancet Digital Health 5 (2), e93-e101, 2023
Maßnahmen zur Bewältigung der COVID-19-Pandemie in Deutschland: nichtpharmakologische und pharmakologische Ansätze
U Grote, M Arvand, S Brinkwirth, M Brunke, U Buchholz, T Eckmanns, ...
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 64 (4), 435, 2021
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