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Kevin H. Gardner
Kevin H. Gardner
Director, Structural Biology Initiative - CUNY Advanced Science Research Center; Professor – CCNY
Verified email at gc.cuny.edu - Homepage
Title
Cited by
Cited by
Year
Structural basis of a phototropin light switch
SM Harper, LC Neil, KH Gardner
Science 301 (5639), 1541-1544, 2003
9292003
THE USE OF 2H, 13C, 15N MULTIDIMENSIONAL NMR GTO STUDY THE STRUCTURE AND DYNAMICS OF PROTEINS
KH Gardner, LE Kay
Annual review of biophysics and biomolecular structure 27 (1), 357-406, 1998
8101998
Targeting renal cell carcinoma with a HIF-2 antagonist
W Chen, H Hill, A Christie, MS Kim, E Holloman, A Pavia-Jimenez, ...
Nature 539 (7627), 112-117, 2016
6662016
A robust and cost-effective method for the production of Val, Leu, Ile (δ1) methyl-protonated 15N-, 13C-, 2H-labeled proteins
NK Goto, KH Gardner, GA Mueller, RC Willis, LE Kay
Journal of biomolecular NMR 13, 369-374, 1999
6371999
White collar-1, a DNA binding transcription factor and a light sensor
Q He, P Cheng, Y Yang, L Wang, KH Gardner, Y Liu
Science 297 (5582), 840-843, 2002
5142002
Evolutionary information for specifying a protein fold
M Socolich, SW Lockless, WP Russ, H Lee, KH Gardner, R Ranganathan
Nature 437 (7058), 512-518, 2005
5122005
An optogenetic gene expression system with rapid activation and deactivation kinetics
LB Motta-Mena, A Reade, MJ Mallory, S Glantz, OD Weiner, KW Lynch, ...
Nature chemical biology 10 (3), 196-202, 2014
3912014
Selective methyl group protonation of perdeuterated proteins
MK Rosen, KH Gardner, RC Willis, WE Parris, T Pawson, LE Kay
Journal of molecular biology 263 (5), 627-636, 1996
3721996
Disruption of the LOV− Jα helix interaction activates phototropin kinase activity
SM Harper, JM Christie, KH Gardner
Biochemistry 43 (51), 16184-16192, 2004
3672004
Production and incorporation of 15N, 13C, 2H (1H-δ1 methyl) isoleucine into proteins for multidimensional NMR studies
KH Gardner, LE Kay
Journal of the American Chemical Society 119 (32), 7599-7600, 1997
3451997
Global folds of highly deuterated, methyl-protonated proteins by multidimensional NMR
KH Gardner, MK Rosen, LE Kay
Biochemistry 36 (6), 1389-1401, 1997
3351997
Allosteric inhibition of hypoxia inducible factor-2 with small molecules
TH Scheuermann, Q Li, HW Ma, J Key, L Zhang, R Chen, JA Garcia, ...
Nature chemical biology 9 (4), 271-276, 2013
3152013
Artificial ligand binding within the HIF2α PAS-B domain of the HIF2 transcription factor
TH Scheuermann, DR Tomchick, M Machius, Y Guo, RK Bruick, ...
Proceedings of the National Academy of Sciences 106 (2), 450-455, 2009
3082009
Structural basis for PAS domain heterodimerization in the basic helix–loop–helix-PAS transcription factor hypoxia-inducible factor
PJA Erbel, PB Card, O Karakuzu, RK Bruick, KH Gardner
Proceedings of the National Academy of Sciences 100 (26), 15504-15509, 2003
2732003
Solution NMR spectroscopy beyond 25 kDa
LE Kay, KH Gardner
Current opinion in structural biology 7 (5), 722-731, 1997
2441997
Identification of small-molecule antagonists that inhibit an activator: coactivator interaction
JL Best, CA Amezcua, B Mayr, L Flechner, CM Murawsky, B Emerson, ...
Proceedings of the National Academy of Sciences 101 (51), 17622-17627, 2004
2392004
Rationally improving LOV domain–based photoswitches
D Strickland, X Yao, G Gawlak, MK Rosen, KH Gardner, TR Sosnick
Nature methods 7 (8), 623-626, 2010
2292010
PAS domain-mediated WC-1/WC-2 interaction is essential for maintaining the steady-state level of WC-1 and the function of both proteins in circadian clock and light responses …
P Cheng, Y Yang, KH Gardner, Y Liu
Molecular and Cellular Biology 22 (2), 517-524, 2002
2192002
Structural basis of photosensitivity in a bacterial light-oxygen-voltage/helix-turn-helix (LOV-HTH) DNA-binding protein
AI Nash, R McNulty, ME Shillito, TE Swartz, RA Bogomolni, H Luecke, ...
Proceedings of the National Academy of Sciences 108 (23), 9449-9454, 2011
2162011
Structure of a bacterial BLUF photoreceptor: insights into blue light-mediated signal transduction
A Jung, T Domratcheva, M Tarutina, Q Wu, W Ko, RL Shoeman, ...
Proceedings of the National Academy of Sciences 102 (35), 12350-12355, 2005
2162005
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