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Nick Franks
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Molecular and cellular mechanisms of general anaesthesia
NP Franks, WR Lieb
Nature 367 (6464), 607-614, 1994
22311994
Crystal structure of human serum albumin complexed with fatty acid reveals an asymmetric distribution of binding sites
S Curry, H Mandelkow, P Brick, N Franks
Nature structural biology 5 (9), 827-835, 1998
15871998
General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal
NP Franks
Nature Reviews Neuroscience 9 (5), 370-386, 2008
13732008
The α2-Adrenoceptor Agonist Dexmedetomidine Converges on an Endogenous Sleep-promoting Pathway to Exert Its Sedative Effects
LE Nelson, J Lu, T Guo, CB Saper, NP Franks, M Maze
The Journal of the American Society of Anesthesiologists 98 (2), 428-436, 2003
11642003
Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes
E Conti, NP Franks, P Brick
Structure 4 (3), 287-298, 1996
8561996
Do general anaesthetics act by competitive binding to specific receptors
NP Franks, WR Lieb
Nature 310 (5978), 599-601, 1984
7671984
The sedative component of anesthesia is mediated by GABAA receptors in an endogenous sleep pathway
LE Nelson, TZ Guo, J Lu, CB Saper, NP Franks, M Maze
Nature neuroscience 5 (10), 979-984, 2002
6782002
Binding of the general anesthetics propofol and halothane to human serum albumin: high resolution crystal structures
AA Bhattacharya, S Curry, NP Franks
Journal of Biological Chemistry 275 (49), 38731-38738, 2000
6542000
How does xenon produce anaesthesia?
NP Franks, R Dickinson, SLM De Sousa, AC Hall, WR Lieb
Nature 396 (6709), 324-324, 1998
6471998
Fatty acid binding to human serum albumin: new insights from crystallographic studies
S Curry, P Brick, NP Franks
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 1999
6181999
Molecular mechanisms of general anaesthesia
NP Franks, WR Lieb
Nature 300 (5892), 487-493, 1982
5951982
Structural analysis of hydrated egg lecithin and cholesterol bilayers II. Neutron diffraction
DL Worcester, NP Franks
Journal of molecular biology 100 (3), 359-378, 1976
5021976
Molecular targets underlying general anaesthesia
NP Franks
British journal of pharmacology 147 (S1), S72-S81, 2006
4542006
Dexmedetomidine produces its neuroprotective effect via the α2A-adrenoceptor subtype
D Ma, M Hossain, N Rajakumaraswamy, M Arshad, RD Sanders, ...
European journal of pharmacology 502 (1-2), 87-97, 2004
3892004
Two-pore-domain K+ channels are a novel target for the anesthetic gases xenon, nitrous oxide, and cyclopropane
M Gruss, TJ Bushell, DP Bright, WR Lieb, A Mathie, NP Franks
Molecular pharmacology 65 (2), 443-452, 2004
3882004
Stereospecific effects of inhalational general anesthetic optical isomers on nerve ion channels
NP Franks, WR Lieb
Science 254 (5030), 427-430, 1991
3541991
Structural analysis of hydrated egg lecithin and cholesterol bilayers I. X-ray diffraction
NP Franks
Journal of molecular biology 100 (3), 345-358, 1976
3511976
Where do general anaesthetics act?
NP Franks, WR Lieb
Nature 274 (5669), 339-342, 1978
3471978
Contrasting synaptic actions of the inhalational general anesthetics isoflurane and xenon
SLM de Sousa, R Dickinson, WR Lieb, NP Franks
The Journal of the American Society of Anesthesiologists 92 (4), 1055-1066, 2000
3412000
Xenon mitigates isoflurane-induced neuronal apoptosis in the developing rodent brain
D Ma, P Williamson, A Januszewski, MC Nogaro, M Hossain, LP Ong, ...
The Journal of the American Society of Anesthesiologists 106 (4), 746-753, 2007
3342007
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