| Molecular and cellular mechanisms of general anaesthesia NP Franks, WR Lieb Nature 367 (6464), 607-614, 1994 | 2281 | 1994 |
| Crystal structure of human serum albumin complexed with fatty acid reveals an asymmetric distribution of binding sites S Curry, H Mandelkow, P Brick, N Franks Nature structural biology 5 (9), 827-835, 1998 | 1638 | 1998 |
| General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal NP Franks Nature Reviews Neuroscience 9 (5), 370-386, 2008 | 1442 | 2008 |
| The α2-Adrenoceptor Agonist Dexmedetomidine Converges on an Endogenous Sleep-promoting Pathway to Exert Its Sedative Effects LE Nelson, J Lu, T Guo, CB Saper, NP Franks, M Maze The Journal of the American Society of Anesthesiologists 98 (2), 428-436, 2003 | 1223 | 2003 |
| Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes E Conti, NP Franks, P Brick Structure 4 (3), 287-298, 1996 | 880 | 1996 |
| Do general anaesthetics act by competitive binding to specific receptors NP Franks, WR Lieb Nature 310 (5978), 599-601, 1984 | 770 | 1984 |
| The sedative component of anesthesia is mediated by GABAA receptors in an endogenous sleep pathway LE Nelson, TZ Guo, J Lu, CB Saper, NP Franks, M Maze Nature neuroscience 5 (10), 979-984, 2002 | 705 | 2002 |
| Fatty acid binding to human serum albumin: new insights from crystallographic studies S Curry, P Brick, NP Franks Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 1999 | 674 | 1999 |
| Binding of the general anesthetics propofol and halothane to human serum albumin: high resolution crystal structures AA Bhattacharya, S Curry, NP Franks Journal of Biological Chemistry 275 (49), 38731-38738, 2000 | 663 | 2000 |
| How does xenon produce anaesthesia? NP Franks, R Dickinson, SLM De Sousa, AC Hall, WR Lieb Nature 396 (6709), 324-324, 1998 | 663 | 1998 |
| Molecular mechanisms of general anaesthesia NP Franks, WR Lieb Nature 300 (5892), 487-493, 1982 | 594 | 1982 |
| Structural analysis of hydrated egg lecithin and cholesterol bilayers II. Neutron diffraction DL Worcester, NP Franks Journal of molecular biology 100 (3), 359-378, 1976 | 504 | 1976 |
| Molecular targets underlying general anaesthesia NP Franks British journal of pharmacology 147 (S1), S72-S81, 2006 | 466 | 2006 |
| Dexmedetomidine produces its neuroprotective effect via the α2A-adrenoceptor subtype D Ma, M Hossain, N Rajakumaraswamy, M Arshad, RD Sanders, ... European journal of pharmacology 502 (1-2), 87-97, 2004 | 405 | 2004 |
| Two-pore-domain K+ channels are a novel target for the anesthetic gases xenon, nitrous oxide, and cyclopropane M Gruss, TJ Bushell, DP Bright, WR Lieb, A Mathie, NP Franks Molecular pharmacology 65 (2), 443-452, 2004 | 400 | 2004 |
| Stereospecific effects of inhalational general anesthetic optical isomers on nerve ion channels NP Franks, WR Lieb Science 254 (5030), 427-430, 1991 | 359 | 1991 |
| Structural analysis of hydrated egg lecithin and cholesterol bilayers I. X-ray diffraction NP Franks Journal of molecular biology 100 (3), 345-358, 1976 | 349 | 1976 |
| Contrasting synaptic actions of the inhalational general anesthetics isoflurane and xenon SLM de Sousa, R Dickinson, WR Lieb, NP Franks The Journal of the American Society of Anesthesiologists 92 (4), 1055-1066, 2000 | 345 | 2000 |
| Xenon and hypothermia combine to provide neuroprotection from neonatal asphyxia D Ma, M Hossain, A Chow, M Arshad, RM Battson, RD Sanders, ... Annals of neurology 58 (2), 182-193, 2005 | 344 | 2005 |
| Where do general anaesthetics act? NP Franks, WR Lieb Nature 274 (5669), 339-342, 1978 | 343 | 1978 |
