| Decreased expression of N-myc precedes retinoic acid-induced morphological differentiation of human neuroblastoma CJ Thiele, CP Reynolds, MA Israel Nature 313 (6001), 404-406, 1985 | 781 | 1985 |
| Adrenomedullin expression in human tumor cell lines Its potential role as an autocrine growth factor MJ Miller, A Martínez, EJ Unsworth, CJ Thiele, TW Moody, T Elsasser, ... Journal of Biological Chemistry 271 (38), 23345-23351, 1996 | 423 | 1996 |
| Induction of TrkB by retinoic acid mediates biologic responsiveness to BDNF and differentiation of human neuroblastoma cells DR Kaplan, K Matsumoto, E Lucarelli, CJ Thiele Neuron 11, 1-20, 1993 | 415 | 1993 |
| Glycogen synthase kinase 3β (GSK3β) mediates 6‐hydroxydopamine‐induced neuronal death G Chen, KA Bower, C Ma, S Fang, CJ Thiele, JIA Luo The FASEB journal 18 (10), 1162-1164, 2004 | 376 | 2004 |
| The MYCN oncogene is a direct target of miR-34a JS Wei, YK Song, S Durinck, QR Chen, ATC Cheuk, P Tsang, Q Zhang, ... Oncogene 27 (39), 5204-5213, 2008 | 360 | 2008 |
| Enhancement of cellular src gene product associated tyrosyl kinase activity following polyoma virus infection and transformation JB Bolen, CJ Thiele, MA Israel, W Yonemoto, LA Lipsich, JS Brugge Cell 38 (3), 767-777, 1984 | 356 | 1984 |
| Repression of the gene encoding the TGF-β type II receptor is a major target of the EWS-FLI1 oncoprotein KB Hahm, K Cho, C Lee, YH Im, J Chang, SG Choi, PHB Sorensen, ... Nature genetics 23 (2), 222-227, 1999 | 327 | 1999 |
| On Trk—The TrkB Signal Transduction Pathway Is an Increasingly Important Target in Cancer Biology CJ Thiele, Z Li, AE McKee Clinical cancer research 15 (19), 5962-5967, 2009 | 314 | 2009 |
| MS-27-275, an inhibitor of histone deacetylase, has marked in vitro and in vivo antitumor activity against pediatric solid tumors J Jaboin, J Wild, H Hamidi, C Khanna, CJ Kim, R Robey, SE Bates, ... Cancer research 62 (21), 6108-6115, 2002 | 313 | 2002 |
| Expression of Brain-derived Neurotrophic Factor and p145TrkB Affects Survival, Differentiation, and Invasiveness of Human Neuroblastoma Cells K Matsumoto, RK Wada, JM Yamashiro, DR Kaplan, CJ Thiele Cancer research 55 (8), 1798-1806, 1995 | 278 | 1995 |
| Brain-derived neurotrophic factor activation of TrkB induces vascular endothelial growth factor expression via hypoxia-inducible factor-1α in neuroblastoma cells K Nakamura, KC Martin, JK Jackson, K Beppu, CW Woo, CJ Thiele Cancer research 66 (8), 4249-4255, 2006 | 270 | 2006 |
| Brain-derived neurotrophic factor activation of TrkB protects neuroblastoma cells from chemotherapy-induced apoptosis via phosphatidylinositol 3′-kinase pathway J Jaboin, CJ Kim, DR Kaplan, CJ Thiele Cancer research 62 (22), 6756-6763, 2002 | 249 | 2002 |
| The role of INI1 and the SWI/SNF complex in the development of rhabdoid tumors: meeting summary from the workshop on childhood atypical teratoid/rhabdoid tumors JA Biegel, G Kalpana, ES Knudsen, RJ Packer, CWM Roberts, CJ Thiele, ... Cancer research 62 (1), 323-328, 2002 | 235 | 2002 |
| EZH2 Mediates Epigenetic Silencing of Neuroblastoma Suppressor Genes CASZ1, CLU, RUNX3, and NGFR C Wang, Z Liu, CW Woo, Z Li, L Wang, JS Wei, VE Marquez, SE Bates, ... Cancer research 72 (1), 315-324, 2012 | 222 | 2012 |
| Neuroblastoma cells isolated from bone marrow metastases contain a naturally enriched tumor-initiating cell LM Hansford, AE McKee, L Zhang, RE George, JT Gerstle, PS Thorner, ... Cancer research 67 (23), 11234-11243, 2007 | 211 | 2007 |
| Effect of imatinib mesylate on neuroblastoma tumorigenesis and vascular endothelial growth factor expression K Beppu, J Jaboine, MS Merchant, CL Mackall, CJ Thiele Journal of the National Cancer Institute 96 (1), 46-55, 2004 | 188 | 2004 |
| Induction of caspase 8 by interferon γ renders some neuroblastoma (NB) cells sensitive to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) but reveals that a … X Yang, MS Merchant, ME Romero, M Tsokos, LH Wexler, U Kontny, ... Cancer research 63 (5), 1122-1129, 2003 | 160 | 2003 |
| CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2 L Chen, G Alexe, NV Dharia, L Ross, AB Iniguez, AS Conway, EJ Wang, ... The Journal of clinical investigation 128 (1), 446-462, 2018 | 146 | 2018 |
| Topotecan blocks hypoxia-inducible factor-1α and vascular endothelial growth factor expression induced by insulin-like growth factor-I in neuroblastoma cells K Beppu, K Nakamura, WM Linehan, A Rapisarda, CJ Thiele Cancer research 65 (11), 4775-4781, 2005 | 138 | 2005 |
| Differential protooncogene expression characterizes histopathologically indistinguishable tumors of the peripheral nervous system. CJ Thiele, C McKeon, TJ Triche, RA Ross, CP Reynolds, MA Israel The Journal of clinical investigation 80 (3), 804-811, 1987 | 132 | 1987 |
Javed KhanDeputy Branch Chief Genetics Branch, Senior Investigator, Center for Cancer Research, NCI, NIHVerified email at mail.nih.gov
