Ayodeji ASUNI
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Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements
AA Asuni, A Boutajangout, D Quartermain, EM Sigurdsson
The Journal of Neuroscience 27 (34), 9115, 2007
GSK-3β inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila
A Mudher, D Shepherd, TA Newman, P Mildren, JP Jukes, A Squire, ...
Molecular psychiatry 9 (5), 522-530, 2004
Parkinson's disease α-synuclein mutations exhibit defective axonal transport in cultured neurons
AR Saha, J Hill, MA Utton, AA Asuni, S Ackerley, AJ Grierson, CC Miller, ...
Journal of cell science 117 (7), 1017-1024, 2004
An attenuated immune response is sufficient to enhance cognition in an Alzheimer's disease mouse model immunized with amyloid-β derivatives
EM Sigurdsson, E Knudsen, A Asuni, C Fitzer-Attas, D Sage, ...
The Journal of neuroscience 24 (28), 6277, 2004
Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-Jun terminal kinase
A Mudher, S Chapman, J Richardson, A Asuni, G Gibb, C Pollard, ...
The Journal of Neuroscience 21 (14), 4987-4995, 2001
Vaccination of Alzheimer's model mice with Aβ derivative in alum adjuvant reduces Aβ burden without microhemorrhages
AA Asuni, A Boutajangout, H Scholtzova, E Knudsen, YS Li, ...
European Journal of Neuroscience 24 (9), 2530-2542, 2006
Immunotherapy for clearing pathological tau conformers
E Sigurdsson, A Asuni
US Patent App. 11/693,375, 2008
A non-toxic ligand for voxel-based MRI analysis of plaques in AD transgenic mice
EM Sigurdsson, YZ Wadghiri, L Mosconi, JA Blind, E Knudsen, A Asuni, ...
Neurobiology of aging 29 (6), 836-847, 2008
Blocking the interaction between apolipoprotein E and Aβ reduces intraneuronal accumulation of Aβ and inhibits synaptic degeneration
MA Kuszczyk, S Sanchez, J Pankiewicz, J Kim, M Duszczyk, M Guridi, ...
The American journal of pathology 182 (5), 1750-1768, 2013
Morphological and functional abnormalities in mitochondria associated with synaptic degeneration in prion disease
Z Sisková, DJ Mahad, C Pudney, G Campbell, M Cadogan, A Asuni, ...
The American journal of pathology 177 (3), 1411, 2010
GSK3α exhibits β‐catenin and tau directed kinase activities that are modulated by Wnt
AA Asuni, C Hooper, CH Reynolds, S Lovestone, BH Anderton, R Killick
European Journal of Neuroscience 24 (12), 3387-3392, 2006
The slow axonal transport of the microtubule-associated protein tau and the transport rates of different isoforms and mutants in cultured neurons
MA Utton, J Connell, AA Asuni, M van Slegtenhorst, M Hutton, R de Silva, ...
The Journal of neuroscience 22 (15), 6394-6400, 2002
Expression of the small heat shock protein family in the mouse CNS: differential anatomical and biochemical compartmentalization
S Quraishe, A Asuni, WC Boelens, V O'Connor, A Wyttenbach
Neuroscience 153 (2), 483-491, 2008
Blocking the apoE/Aβ interaction ameliorates Aβ-related pathology in APOE ε2 and ε4 targeted replacement Alzheimer model mice
JE Pankiewicz, M Guridi, J Kim, AA Asuni, S Sanchez, PM Sullivan, ...
Acta neuropathologica communications 2, 1-11, 2014
Presenilin 1 independently regulates β-catenin stability and transcriptional activity
R Killick, CC Pollard, AA Asuni, AK Mudher, JC Richardson, HT Rupniak, ...
Journal of Biological Chemistry 276 (51), 48554-48561, 2001
Tau fragments for immunotherapy
E Sigurdsson, A Asuni
US Patent 8,012,936, 2011
Photoaffinity labeling of the benzodiazepine binding site of α1β3γ2 γ-aminobutyric acidA receptors with flunitrazepam identifies a subset of ligands that interact directly with …
RM McKernan, S Farrar, I Collins, F Emms, A Asuni, K Quirk, H Broughton
Molecular Pharmacology 54 (1), 33-43, 1998
Highly specific and selective anti-pS396-tau antibody C10. 2 targets seeding-competent tau
N Rosenqvist, AA Asuni, CR Andersson, S Christensen, JA Daechsel, ...
Alzheimer's & Dementia: Translational Research & Clinical Interventions 4 …, 2018
Efficient gene delivery to primary neuron cultures using a synthetic peptide vector system
L Collins, AA Asuni, BH Anderton, JW Fabre
Journal of neuroscience methods 125 (1-2), 113-120, 2003
Truncated apoE forms tangle-like structures in a neuronal cell line
MC Ljungberg, R Dayanandan, A Asuni, TH Rupniak, BH Anderton, ...
Neuroreport 13 (6), 867-870, 2002
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