Etienne Decroly
Etienne Decroly
DR1 CNRS Aix Marseille university
Verified email at - Homepage
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The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade
B Coutard, C Valle, X De Lamballerie, B Canard, NG Seidah, E Decroly
Antiviral research 176, 104742, 2020
One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities
L Subissi, CC Posthuma, A Collet, JC Zevenhoven-Dobbe, ...
Proceedings of the National Academy of Sciences 111 (37), E3900-E3909, 2014
The nonstructural proteins directing coronavirus RNA synthesis and processing
EJ Snijder, E Decroly, J Ziebuhr
Advances in virus research 96, 59-126, 2016
Conventional and unconventional mechanisms for capping viral mRNA
E Decroly, F Ferron, J Lescar, B Canard
Nature Reviews Microbiology 10 (1), 51-65, 2012
Structure and functionality in flavivirus NS-proteins: perspectives for drug design
M Bollati, K Alvarez, R Assenberg, C Baronti, B Canard, S Cook, ...
Antiviral research 87 (2), 125-148, 2010
In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replication
F Touret, M Gilles, K Barral, A Nougairède, J Van Helden, E Decroly, ...
Scientific reports 10 (1), 13093, 2020
In Vitro Reconstitution of SARS-Coronavirus mRNA Cap Methylation
M Bouvet, C Debarnot, I Imbert, B Selisko, EJ Snijder, B Canard, ...
PLoS pathogens 6 (4), e1000863, 2010
Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA
F Ferron, L Subissi, AT Silveira De Morais, NTT Le, M Sevajol, L Gluais, ...
Proceedings of the National Academy of Sciences 115 (2), E162-E171, 2018
Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2′-O-methyltransferase nsp10/nsp16 complex
E Decroly, C Debarnot, F Ferron, M Bouvet, B Coutard, I Imbert, L Gluais, ...
PLoS pathogens 7 (5), e1002059, 2011
RNA 3'-end mismatch excision by the severe acute respiratory syndrome coronavirus nonstructural protein nsp10/nsp14 exoribonuclease complex
M Bouvet, I Imbert, L Subissi, L Gluais, B Canard, E Decroly
Proceedings of the National Academy of Sciences 109 (24), 9372-9377, 2012
Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites
A Shannon, NTT Le, B Selisko, C Eydoux, K Alvarez, JC Guillemot, ...
Antiviral research 178, 104793, 2020
Coronavirus Nonstructural Protein 16 Is a Cap-0 Binding Enzyme Possessing (Nucleoside-2′O)-Methyltransferase Activity
E Decroly, I Imbert, B Coutard, M Bouvet, B Selisko, K Alvarez, ...
Journal of virology 82 (16), 8071-8084, 2008
Maturation of HIV envelope glycoprotein precursors by cellular endoproteases
M Moulard, E Decroly
Biochimica et Biophysica Acta (BBA)-Reviews on Biomembranes 1469 (3), 121-132, 2000
Insights into RNA synthesis, capping, and proofreading mechanisms of SARS-coronavirus
M Sevajol, L Subissi, E Decroly, B Canard, I Imbert
Virus research 194, 90-99, 2014
Coronavirus Nsp10, a critical co-factor for activation of multiple replicative enzymes
M Bouvet, A Lugari, CC Posthuma, JC Zevenhoven, S Bernard, S Betzi, ...
Journal of Biological Chemistry 289 (37), 25783-25796, 2014
Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis
A Shannon, B Selisko, NTT Le, J Huchting, F Touret, G Piorkowski, ...
Nature communications 11 (1), 4682, 2020
SARS-CoV ORF1b-encoded nonstructural proteins 12–16: replicative enzymes as antiviral targets
L Subissi, I Imbert, F Ferron, A Collet, B Coutard, E Decroly, B Canard
Antiviral research 101, 122-130, 2014
The pore-forming toxin proaerolysin is activated by furin
L Abrami, M Fivaz, E Decroly, NG Seidah, F Jean, G Thomas, SH Leppla, ...
Journal of Biological Chemistry 273 (49), 32656-32661, 1998
FTSJ3 is an RNA 2′-O-methyltransferase recruited by HIV to avoid innate immune sensing
M Ringeard, V Marchand, E Decroly, Y Motorin, Y Bennasser
Nature 565 (7740), 500-504, 2019
The convertases furin and PC1 can both cleave the human immunodeficiency virus (HIV)-1 envelope glycoprotein gp160 into gp120 (HIV-1 SU) and gp41 (HIV-I TM).
E Decroly, M Vandenbranden, JM Ruysschaert, J Cogniaux, GS Jacob, ...
Journal of Biological Chemistry 269 (16), 12240-12247, 1994
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