Carl Hansen
Carl Hansen
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A robust and scalable microfluidic metering method that allows protein crystal growth by free interface diffusion
CL Hansen, E Skordalakes, JM Berger, SR Quake
Proceedings of the National Academy of Sciences 99 (26), 16531-16536, 2002
Long-term monitoring of bacteria undergoing programmed population control in a microchemostat
FK Balagaddé, L You, CL Hansen, FH Arnold, SR Quake
Science 309 (5731), 137-140, 2005
Nucleic acid amplification utilizing microfluidic devices
MM Enzelberger, J Liu, SR Quake
US Patent 6,960,437, 2005
Microfluidic synthesis of highly potent limit-size lipid nanoparticles for in vivo delivery of siRNA
NM Belliveau, J Huft, PJC Lin, S Chen, AKK Leung, TJ Leaver, AW Wild, ...
Molecular Therapy-Nucleic Acids 1, 2012
Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution
P Eirew, A Steif, J Khattra, G Ha, D Yap, H Farahani, K Gelmon, S Chia, ...
Nature 518 (7539), 422-426, 2015
High-throughput microfluidic single-cell RT-qPCR
AK White, M VanInsberghe, OI Petriv, M Hamidi, D Sikorski, MA Marra, ...
Proceedings of the National Academy of Sciences 108 (34), 13999-14004, 2011
The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates
BE Jones, PL Brown-Augsburger, KS Corbett, K Westendorf, J Davies, ...
Science translational medicine 13 (593), eabf1906, 2021
Bottom-up design and synthesis of limit size lipid nanoparticle systems with aqueous and triglyceride cores using millisecond microfluidic mixing
IV Zhigaltsev, N Belliveau, I Hafez, AKK Leung, J Huft, C Hansen, ...
Langmuir 28 (7), 3633-3640, 2012
Microfluidics in structural biology: smaller, faster… better
C Hansen, SR Quake
Current opinion in structural biology 13 (5), 538-544, 2003
Small but perfectly formed? Successes, challenges, and opportunities for microfluidics in the chemical and biological sciences
DT Chiu, AJ Demello, D Di Carlo, PS Doyle, C Hansen, RM Maceiczyk, ...
Chem 2 (2), 201-223, 2017
Megapixel digital PCR
KA Heyries, C Tropini, M VanInsberghe, C Doolin, OI Petriv, A Singhal, ...
Nature methods 8 (8), 649-651, 2011
Solving the “world-to-chip” interface problem with a microfluidic matrix
J Liu, C Hansen, SR Quake
Analytical chemistry 75 (18), 4718-4723, 2003
High-throughput analysis of single hematopoietic stem cell proliferation in microfluidic cell culture arrays
V Lecault, M VanInsberghe, S Sekulovic, DJHF Knapp, S Wohrer, ...
Nature methods 8 (7), 581-586, 2011
Microfabricated elastomeric valve and pump systems
MA Unger, HP Chou, TA Thorsen, A Scherer, SR Quake, MM Enzelberger, ...
US Patent 6,899,137, 2005
LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants
K Westendorf, S Žentelis, L Wang, D Foster, P Vaillancourt, M Wiggin, ...
Cell reports 39 (7), 2022
Nucleic acid amplification using microfluidic devices
MM Enzelberger, CL Hansen, J Liu, SR Quake, C Ma
US Patent 7,833,708, 2010
Microfabricated elastomeric valve and pump systems
MA Unger, HP Chou, TA Thorsen, A Scherer, SR Quake, J Liu, ML Adams, ...
US Patent 6,929,030, 2005
Lipid nanoparticles containing siRNA synthesized by microfluidic mixing exhibit an electron-dense nanostructured core
AKK Leung, IM Hafez, S Baoukina, NM Belliveau, IV Zhigaltsev, ...
The Journal of Physical Chemistry C 116 (34), 18440-18450, 2012
High throughput screening of crystallization of materials
CL Hansen, SR Quake, JM Berger
US Patent 7,195,670, 2007
A programmable droplet-based microfluidic device applied to multiparameter analysis of single microbes and microbial communities
K Leung, H Zahn, T Leaver, KM Konwar, NW Hanson, AP Pagé, CC Lo, ...
Proceedings of the National Academy of Sciences 109 (20), 7665-7670, 2012
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