DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139 EP Rogakou, DR Pilch, AH Orr, VS Ivanova, WM Bonner Journal of biological chemistry 273 (10), 5858-5868, 1998 | 6461 | 1998 |
Megabase chromatin domains involved in DNA double-strand breaks in vivo EP Rogakou, C Boon, C Redon, WM Bonner The Journal of cell biology 146 (5), 905-916, 1999 | 3055 | 1999 |
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage TT Paull, EP Rogakou, V Yamazaki, CU Kirchgessner, M Gellert, ... Current Biology 10 (15), 886-895, 2000 | 2687 | 2000 |
Histone H2a variants H2AX and H2AZ C Redon, D Pilch, E Rogakou, O Sedelnikova, K Newrock, W Bonner Current opinion in genetics & development 12 (2), 162-169, 2002 | 1088 | 2002 |
Recombinational DNA double-strand breaks in mice precede synapsis SK Mahadevaiah, J Turner, F Baudat, EP Rogakou, P de Boer, ... Nature genetics 27 (3), 271-276, 2001 | 962 | 2001 |
Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139 EP Rogakou, W Nieves-Neira, C Boon, Y Pommier, WM Bonner Journal of Biological Chemistry 275 (13), 9390-9395, 2000 | 879 | 2000 |
Quantitative Detection of 125IdU-Induced DNA Double-Strand Breaks with γ-H2AX Antibody OA Sedelnikova, EP Rogakou, IG Panyutin, WM Bonner Radiation research 158 (4), 486-492, 2002 | 863 | 2002 |
Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I … T Furuta, H Takemura, ZY Liao, GJ Aune, C Redon, OA Sedelnikova, ... Journal of Biological Chemistry 278 (22), 20303-20312, 2003 | 570 | 2003 |
Response to RAG-mediated V (D) J cleavage by NBS1 and γ-H2AX HT Chen, A Bhandoola, MJ Difilippantonio, J Zhu, MJ Brown, X Tai, ... Science 290 (5498), 1962-1964, 2000 | 377 | 2000 |
Yeast histone 2A serine 129 is essential for the efficient repair of checkpoint‐blind DNA damage C Redon, DR Pilch, EP Rogakou, AH Orr, NF Lowndes, WM Bonner EMBO reports 4 (7), 678-684, 2003 | 284 | 2003 |
Complex DNA damage: a route to radiation-induced genomic instability and carcinogenesis IV Mavragani, Z Nikitaki, MP Souli, A Aziz, S Nowsheen, K Aziz, ... Cancers 9 (7), 91, 2017 | 166 | 2017 |
Genome instability and γH2AX A Georgoulis, CE Vorgias, GP Chrousos, EP Rogakou International journal of molecular sciences 18 (9), 1979, 2017 | 156 | 2017 |
Histone variants of H2A and H3 families are regulated during in vitro aging in the same manner as during differentiation EP Rogakou, KE Sekeri–Pataryas Experimental gerontology 34 (6), 741-754, 1999 | 99 | 1999 |
Histone H2AX is phosphorylated at sites of retroviral DNA integration but is dispensable for postintegration repair R Daniel, J Ramcharan, E Rogakou, KD Taganov, JG Greger, W Bonner, ... Journal of Biological Chemistry 279 (44), 45810-45814, 2004 | 93 | 2004 |
Rapid histone extraction for electrophoretic analysis EP Rogakou, C Redon, C Boon, K Johnson, WM Bonner Biotechniques 28 (1), 38-46, 2000 | 20 | 2000 |
Anti-γ-H2A antibody, fusion proteins thereof and method and kit for determining DNA double-stranded breaks WM Bonner, E Rogakou US Patent 6,362,317, 2002 | 13 | 2002 |
Interplay between γH2AX and 53BP1 pathways in DNA double-strand break repair response F Chronis, EP Rogakou Apoptosis, senescence, and cancer, 243-263, 2007 | 11 | 2007 |
Histone H2AX serine-139 phosphorylation is induced by the introduction of the initial breaks into DNA as a result of the apoptotic endonuclease EP Rogakou, W Nieves-Niera, C Boon, Y Pommier, WM Bonner Mol Biol Cell 9, 109A-109A, 1998 | 8 | 1998 |
A biochemical marker for differentiation is present in an in vitro aging cell system EP Rogakou, KE Sekeripataryas Biochemical and biophysical research communications 196 (3), 1274-1279, 1993 | 8 | 1993 |
Kit for determining DNA double-stranded breaks with anti-γ-H2A antibodies WM Bonner, E Rogakou US Patent 6,884,873, 2005 | 7 | 2005 |