James Spudich
James Spudich
Professor of Biochemistry, Stanford University
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The regulation of rabbit skeletal muscle contraction: I. Biochemical studies of the interaction of the tropomyosin-troponin complex with actin and the proteolytic fragments of …
JA Spudich, S Watt
Journal of biological chemistry 246 (15), 4866-4871, 1971
Single myosin molecule mechanics: piconewton forces and nanometre steps
JT Finer, RM Simmons, JA Spudich
Nature 368 (6467), 113-119, 1994
[18] Purification of muscle actin
JD Pardee, J Aspudich
Methods in enzymology 85, 164-181, 1982
Disruption of the Dictyostelium myosin heavy chain gene by homologous recombination
A De Lozanne, JA Spudich
Science 236 (4805), 1086-1091, 1987
Fluorescent actin filaments move on myosin fixed to a glass surface.
SJ Kron, JA Spudich
Proceedings of the National Academy of Sciences 83 (17), 6272-6276, 1986
Optimized localization analysis for single-molecule tracking and super-resolution microscopy
KI Mortensen, LS Churchman, JA Spudich, H Flyvbjerg
Nature methods 7 (5), 377-381, 2010
Myosin-V is a processive actin-based motor
AD Mehta, RS Rock, M Rief, JA Spudich, MS Mooseker, RE Cheney
Nature 400 (6744), 590-593, 1999
Single-molecule biomechanics with optical methods
AD Mehta, M Rief, JA Spudich, DA Smith, RM Simmons
Science 283 (5408), 1689-1695, 1999
Quantitative measurements of force and displacement using an optical trap
RM Simmons, JT Finer, S Chu, JA Spudich
Biophysical journal 70 (4), 1813-1822, 1996
Myosin subfragment-1 is sufficient to move actin filaments in vitro
YY Toyoshima, SJ Kron, EM McNally, KR Niebling, C Toyoshima, ...
Nature 328 (6130), 536-539, 1987
Myosin structure and function in cell motility
HM Warrick, JA Spudich
Annual review of cell biology 3 (1), 379-421, 1987
A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice
EM Green, H Wakimoto, RL Anderson, MJ Evanchik, JM Gorham, ...
Science 351 (6273), 617-621, 2016
Nonmuscle contractile proteins: the role of actin and myosin in cell motility and shape determination
M Clarke, JA Spudich
Annual review of biochemistry 46 (1), 797-822, 1977
Movement of myosin-coated fluorescent beads on actin cables in vitro
MP Sheetz, JA Spudich
Nature 303 (5912), 31-35, 1983
How molecular motors work
JA Spudich
Nature 372 (6506), 515-518, 1994
The neck region of the myosin motor domain acts as a lever arm to generate movement.
TQ Uyeda, PD Abramson, JA Spudich
Proceedings of the National Academy of Sciences 93 (9), 4459-4464, 1996
Myosin step size: estimation from slow sliding movement of actin over low densities of heavy meromyosin
TQP Uyeda, SJ Kron, JA Spudich
Journal of molecular biology 214 (3), 699-710, 1990
Myosin-V stepping kinetics: a molecular model for processivity
M Rief, RS Rock, AD Mehta, MS Mooseker, RE Cheney, JA Spudich
Proceedings of the National Academy of Sciences 97 (17), 9482-9486, 2000
[33] Assays for actin sliding movement over myosin-coated surfaces
SJ Kron, YY Toyoshima, TQP Uyeda, JA Spudich
Methods in enzymology 196, 399-416, 1991
Cytoskeletal elements of chick embryo fibroblasts revealed by detergent extraction
S Brown, W Levinson, JA Spudich
Journal of supramolecular structure 5 (2), 119-130, 1976
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