| Proenkephalin A gene products activate a new family of sensory neuron–specific GPCRs PMC Lembo, E Grazzini, T Groblewski, D O'Donnell, MO Roy, J Zhang, ... Nature neuroscience 5 (3), 201-209, 2002 | 438 | 2002 |
| Receptor subtype-specific pronociceptive and analgesic actions of galanin in the spinal cord: selective actions via GalR1 and GalR2 receptors HX Liu, P Brumovsky, R Schmidt, W Brown, K Payza, L Hodzic, C Pou, ... Proceedings of the National Academy of Sciences 98 (17), 9960-9964, 2001 | 251 | 2001 |
| The second galanin receptor GalR2 plays a key role in neurite outgrowth from adult sensory neurons SA Mahoney, R Hosking, S Farrant, FE Holmes, AS Jacoby, J Shine, ... Journal of Neuroscience 23 (2), 416-421, 2003 | 172 | 2003 |
| New diarylmethylpiperazines as potent and selective nonpeptidic δ opioid receptor agonists with increased in vitro metabolic stability N Plobeck, D Delorme, ZY Wei, H Yang, F Zhou, P Schwarz, L Gawell, ... Journal of medicinal chemistry 43 (21), 3878-3894, 2000 | 132 | 2000 |
| Sensory neuron-specific receptor activation elicits central and peripheral nociceptive effects in rats E Grazzini, C Puma, MO Roy, XH Yu, D O'Donnell, R Schmidt, S Dautrey, ... Proceedings of the National Academy of Sciences 101 (18), 7175-7180, 2004 | 118 | 2004 |
| Discovery of evobrutinib: an oral, potent, and highly selective, covalent Bruton’s tyrosine kinase (BTK) inhibitor for the treatment of immunological diseases RD Caldwell, H Qiu, BC Askew, AT Bender, N Brugger, M Camps, ... Journal of Medicinal Chemistry 62 (17), 7643-7655, 2019 | 112 | 2019 |
| Effects of galanin receptor agonists on locus coeruleus neurons X Ma, YG Tong, R Schmidt, W Brown, K Payza, L Hodzic, C Pou, ... Brain research 919 (1), 169-174, 2001 | 99 | 2001 |
| N, N-Diethyl-4-(phenylpiperidin-4-ylidenemethyl) benzamide: a novel, exceptionally selective, potent δ opioid receptor agonist with oral bioavailability and its analogues ZY Wei, W Brown, B Takasaki, N Plobeck, D Delorme, F Zhou, H Yang, ... Journal of medicinal chemistry 43 (21), 3895-3905, 2000 | 86 | 2000 |
| Cyclic. beta.-Casomorphin Analogs with Mixed. mu. Agonist/. delta. Antagonist Properties: Synthesis, Pharmacological Characterization, and Conformational Aspects R Schmidt, D Vogel, C Mrestani-Klaus, W Brandt, K Neubert, NN Chung, ... Journal of medicinal chemistry 37 (8), 1136-1144, 1994 | 69 | 1994 |
| Cyclization studies with tetra‐and pentapeptide sequences corresponding to β‐casomorphins R SCHMIDT, K NEUBERT International Journal of Peptide and Protein Research 37 (6), 502-507, 1991 | 65 | 1991 |
| Structure‐activity relationships of dermorphin analogues containing N‐substituted amino acids in the 2‐position of the peptide sequence R SCHMIDT, A KÁLMÁN, NGAN CHUNG, C LEMIEUX, C HORVÁTH, ... International Journal of Peptide and Protein Research 46 (1), 47-55, 2009 | 59 | 2009 |
| The galanin‐R2 agonist AR‐M1896 reduces glutamate toxicity in primary neural hippocampal cells S Pirondi, M Fernandez, R Schmidt, T Hökfelt, L Giardino, L Calzà Journal of neurochemistry 95 (3), 821-833, 2005 | 58 | 2005 |
| Novel ligands lacking a positive charge for the δ-and μ-opioid receptors PW Schiller, I Berezowska, TMD Nguyen, R Schmidt, C Lemieux, ... Journal of medicinal chemistry 43 (4), 551-559, 2000 | 58 | 2000 |
| Isolation and identification of peptide conformers by reversed-phase high-performance liquid chromatography and NMR at low temperature A Kálmán, F Thunecke, R Schmidt, PW Schiller, C Horváth Journal of Chromatography A 729 (1-2), 155-171, 1996 | 54 | 1996 |
| Turn structures in CGRP C-terminal analogues promote stable arrangements of key residue side chains KA Carpenter, R Schmidt, B von Mentzer, U Haglund, E Roberts, ... Biochemistry 40 (28), 8317-8325, 2001 | 51 | 2001 |
| Subtleties of structure-agonist versus antagonist relationships of opioid peptides and peptidomimetics PW Schiller, G Weltrowska, R Schmidt, I Berezowska, TMD Nguyen, ... Journal of Receptors and Signal Transduction 19 (1-4), 573-588, 1999 | 40 | 1999 |
| The Glycine1 Residue in Cyclic Lactam Analogues of Galanin(1−16)-NH2 Is Important for Stabilizing an N-Terminal Helix KA Carpenter, R Schmidt, SY Yue, L Hodzic, C Pou, K Payza, C Godbout, ... Biochemistry 38 (46), 15295-15304, 1999 | 37 | 1999 |
| Four different types of opioid peptides with mixed μ agonist/δ antagonist properties PW Schiller, G Weltrowska, R Schmidt, TMD Nguyen, I Berezowska, ... Analgesia 1 (4-5), 703-706, 1995 | 37 | 1995 |
| Exploring deltorphin II binding to the third extracellular loop of the δ-opioid receptor I Fadhil, R Schmidt, C Walpole, KA Carpenter Journal of Biological Chemistry 279 (20), 21069-21077, 2004 | 31 | 2004 |
| Novel C-terminus modifications of the Dmt-Tic motif: a new class of dipeptide analogues showing altered pharmacological profiles toward the opioid receptors D Pagé, A Naismith, R Schmidt, M Coupal, M Labarre, M Gosselin, ... Journal of medicinal chemistry 44 (15), 2387-2390, 2001 | 30 | 2001 |
Peter W. SchillerResearch Professor, Clinical Res. Inst..Montreal and Research Prof. Pharmacol., Univ. of MontrealVerified email at ircm.qc.ca
