Local bacteria affect the efficacy of chemotherapeutic drugs P Lehouritis, J Cummins, M Stanton, CT Murphy, FO McCarthy, G Reid, ... Scientific reports 5 (1), 14554, 2015 | 271 | 2015 |
Qualitative and quantitative comparison of the cytotoxic and apoptotic potential of phytosterol oxidation products with their corresponding cholesterol oxidation products E Ryan, J Chopra, F McCarthy, AR Maguire, NM O Brien British Journal of Nutrition 94 (3), 443, 2005 | 157 | 2005 |
Isolation, biological activity and synthesis of the natural product ellipticine and related pyridocarbazoles CM Miller, FO McCarthy RSC Adv., 2012 | 93 | 2012 |
Recent advances in phytosterol oxidation products Y O’Callaghan, FO McCarthy, NM O’Brien Biochemical and Biophysical Research Communications 446 (3), 786-791, 2014 | 80 | 2014 |
Synthesis, isolation and characterisation of β-sitosterol and β-sitosterol oxide derivatives FO McCarthy, J Chopra, A Ford, SA Hogan, JP Kerry, NM O'Brien, E Ryan, ... Org. Biomol. Chem. 3 (16), 3059-3065, 2005 | 80 | 2005 |
Phytosterol oxidation products: their formation, occurrence, and biological effects E Ryan, FO McCarthy, AR Maguire, NM O'Brien Food Reviews International 25 (2), 157-174, 2009 | 79 | 2009 |
Synthesis and evaluation of novel ellipticines as potential anti-cancer agents FM Deane, EC O'Sullivan, AR Maguire, J Gilbert, JA Sakoff, A McCluskey, ... Organic & Biomolecular Chemistry 11 (8), 1334-1344, 2013 | 65 | 2013 |
Tyrosine Kinase Inhibitors. 20. Optimization of Substituted Quinazoline and Pyrido[3,4-d]pyrimidine Derivatives as Orally Active, Irreversible Inhibitors of the … JB Smaill, AJ Gonzales, JA Spicer, H Lee, JE Reed, K Sexton, IW Althaus, ... Journal of Medicinal Chemistry 59 (17), 8103-8124, 2016 | 59 | 2016 |
Cytotoxic and Apoptotic Effects of the Oxidized Derivatives of Stigmasterol in the U937 Human Monocytic Cell Line YC O’Callaghan, DA Foley, NM O’Connell, FO McCarthy, AR Maguire, ... Journal of agricultural and food chemistry, 2010 | 59 | 2010 |
Activation of multiple chemotherapeutic prodrugs by the natural enzymolome of tumour-localised probiotic bacteria P Lehouritis, M Stanton, FO McCarthy, M Jeavons, M Tangney Journal of controlled release 222, 9-17, 2016 | 50 | 2016 |
Synthesis and Characterization of Stigmasterol Oxidation Products DA Foley, Y O’Callaghan, NM O’Brien, FO McCarthy, AR Maguire Journal of agricultural and food chemistry 58 (2), 1165-1173, 2010 | 46 | 2010 |
Synthesis of novel 3, 4-diaryl-5-aminopyrazoles as potential kinase inhibitors LT Pierce, MM Cahill, FO McCarthy Tetrahedron, 2011 | 37 | 2011 |
Synthesis and assessment of the relative toxicity of the oxidised derivatives of campesterol and dihydrobrassicasterol in U937 and HepG2 cells Y O'Callaghan, O Kenny, NM O’Connell, AR Maguire, FO McCarthy, ... Biochimie 95 (3), 496-503, 2013 | 33 | 2013 |
Oxidized derivatives of dihydrobrassicasterol: cytotoxic and apoptotic potential in U937 and HepG2 cells O Kenny, Y O’Callaghan, NM O’Connell, FO McCarthy, AR Maguire, ... Journal of agricultural and food chemistry 60 (23), 5952-5961, 2012 | 33 | 2012 |
Vascular effects of oxysterols and oxyphytosterols in apoE−/− mice O Weingärtner, C Husche, HF Schött, T Speer, M Böhm, CM Miller, ... Atherosclerosis 240 (1), 73-79, 2015 | 32 | 2015 |
Synthesis and biological evaluation of novel isoellipticine derivatives and salts CM Miller, EC O'Sullivan, KJ Devine, FO McCarthy Organic & Biomolecular Chemistry 10 (39), 7912-7921, 2012 | 32 | 2012 |
Synthesis and identification of novel indolo [2,3-a] pyrimido [5,4-c] carbazoles as a new class of anti-cancer agents LT Pierce, MM Cahill, HJ Winfield, FO McCarthy European journal of medicinal chemistry, 2012 | 29 | 2012 |
Emerging targets in the bioactivity of Ellipticines and derivatives E O’ Sullivan, C Miller, F Deane, FO McCarthy Studies in Natural Products Chemistry 39 (6), 189-232, 2012 | 29 | 2012 |
Ellipticine derivative induces potent cytostatic effect in acute myeloid leukaemia cells EG Russell, EC O’Sullivan, CM Miller, J Stanicka, FO McCarthy, TG Cotter Investigational new drugs 32, 1113-1122, 2014 | 28 | 2014 |
Oxidation of sitosterol and transport of its 7-oxygenated products from different tissues in humans and ApoE knockout mice HF Schött, S Baumgartner, C Husche, A Luister, S Friedrichs, CM Miller, ... The Journal of Steroid Biochemistry and Molecular Biology 169, 145-151, 2017 | 24 | 2017 |