François Brial
François Brial
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Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota
L Hoyles, ML Jiménez-Pranteda, J Chilloux, F Brial, A Myridakis, ...
Microbiome 6 (1), 73, 2018
Implication of gut microbiota metabolites in cardiovascular and metabolic diseases
F Brial, A Le Lay, ME Dumas, D Gauguier
Cellular and Molecular Life Sciences 75, 3977-3990, 2018
Human and preclinical studies of the host–gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health
F Brial, J Chilloux, T Nielsen, S Vieira-Silva, G Falony, P Andrikopoulos, ...
Gut 70 (11), 2105-2114, 2021
The natural metabolite 4-cresol improves glucose homeostasis and enhances β-cell function
F Brial, F Alzaid, K Sonomura, Y Kamatani, K Meneyrol, A Le Lay, N Péan, ...
Cell Reports 30 (7), 2306-2320. e5, 2020
Dominant gut Prevotella copri in gastrectomised non-obese diabetic Goto–Kakizaki rats improves glucose homeostasis through enhanced FXR signalling
N Péan, A Le Lay, F Brial, J Wasserscheid, C Rouch, M Vincent, ...
Diabetologia 63, 1223-1235, 2020
Untargeted Mass Spectrometry Lipidomics identifies correlation between serum sphingomyelins and plasma cholesterol
P Zalloua, H Kadar, E Hariri, L Abi Farraj, F Brial, L Hedjazi, A Le Lay, ...
Lipids in health and disease 18, 1-10, 2019
Loss of hepatocyte-nuclear-factor-1α impacts on adult mouse intestinal epithelial cell growth and cell lineages differentiation
CR Lussier, F Brial, SAB Roy, MJ Langlois, EF Verdu, N Rivard, ...
PloS one 5 (8), e12378, 2010
Mitochondrial dysfunction as a hallmark of environmental injury
C Duarte-Hospital, A Tête, F Brial, L Benoit, M Koual, C Tomkiewicz, ...
Cells 11 (1), 110, 2021
Ghrelin Inhibition Restores Glucose Homeostasis in Hepatocyte Nuclear Factor-1α (MODY3)–Deficient Mice
F Brial, CR Lussier, K Belleville, P Sarret, F Boudreau
Diabetes 64 (9), 3314-3320, 2015
Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota. Microbiome 6: 73
L Hoyles, ML Jimenez-Pranteda, J Chilloux, F Brial, A Myridakis, ...
Systems genetics of hepatic metabolome reveals octopamine as a target for non-alcoholic fatty liver disease treatment
F Brial, A Le Lay, L Hedjazi, T Tsang, JF Fearnside, GW Otto, F Alzaid, ...
Scientific Reports 9 (1), 3656, 2019
Plasma and urine metabolomic analyses in aortic valve stenosis reveal shared and biofluid-specific changes in metabolite levels
C Al Hageh, R Rahy, G Khazen, F Brial, RS Khnayzer, D Gauguier, ...
PloS one 15 (11), e0242019, 2020
Diet dependent impact of benzoate on diabetes and obesity in mice
F Brial, F Matsuda, D Gauguier
Biochimie 194, 35-42, 2022
Conserved properties of genetic architecture of renal and fat transcriptomes in rat models of insulin resistance
GW Otto, PJ Kaisaki, F Brial, A Le Lay, JB Cazier, R Mott, D Gauguier
Disease Models & Mechanisms 12 (7), dmm038539, 2019
Microbiome determinants and physiological effects of the benzoate-hippurate microbial-host co-metabolic pathway
F Brial, J Chilloux, T Nielsen, S Vieira-Silva, G Falony, L Hoyles, ...
BioRxiv, 2019.12. 15.876672, 2019
Microbiome Inhibition of IRAK-4 by Trimethylamine Mediates Metabolic and Immune Benefits in High-Fat-Diet-induced Insulin 2 Resistance 3
J Chilloux, F Brial, A Everard, D Smyth, L Zhang, H Plovier, A Myridakis, ...
crosstalk 46, 47, 2018
A phenome-wide association study (PheWAS) to identify the health impacts of 4-cresol sulfate in the Nagahama Study
H Ou, S Kawaguchi, K Sonomura, T Kawaguchi, S Kitada, S Yoshiji, ...
Scientific Reports 13 (1), 13926, 2023
Genetic Architecture of Untargeted Lipidomics in Cardiometabolic-Disease Patients Combines Strong Polygenic Control and Pleiotropy
F Brial, L Hedjazi, K Sonomura, C Al Hageh, P Zalloua, F Matsuda, ...
Metabolites 12 (7), 596, 2022
Mass spectrometry plasma metabolomic profiling identifies metabolites associated with obesity in humans: pathophysiological role of the gut microbial metabolite indolelactic …
F Brial, K Sonomura, J Russick, TA Sato, F Matsuda, D Gauguier, ...
Precision Nutrition 1 (1), 10.1097, 2022
Microbiome inhibition of IRAK-4 by trimethylamine mediates metabolic and immune benefits in high fat diet-induced insulin resistance
ME Dumas, J Chilloux, A Myridakis, L Hoyles, A Everard, H Plovier, ...
Diabetologia 61, S267-S268, 2018
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