Dennis Discher
Cited by
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Matrix elasticity directs stem cell lineage specification
AJ Engler, S Sen, HL Sweeney, DE Discher
Cell 126 (4), 677-689, 2006
Tissue cells feel and respond to the stiffness of their substrate
DE Discher, P Janmey, Y Wang
Science 310 (5751), 1139-1143, 2005
Polymer vesicles
DE Discher, A Eisenberg
Science 297 (5583), 967-973, 2002
Polymersomes: tough vesicles made from diblock copolymers
BM Discher, YY Won, DS Ege, JCM Lee, FS Bates, DE Discher, ...
Science 284 (5417), 1143-1146, 1999
Growth factors, matrices, and forces combine and control stem cells
DE Discher, DJ Mooney, PW Zandstra
Science 324 (5935), 1673-1677, 2009
Shape effects of filaments versus spherical particles in flow and drug delivery
YAN Geng, P Dalhaimer, S Cai, R Tsai, M Tewari, T Minko, DE Discher
Nature nanotechnology 2 (4), 249-255, 2007
Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments
AJ Engler, MA Griffin, S Sen, CG Bönnemann, HL Sweeney, DE Discher
The Journal of cell biology 166 (6), 877-887, 2004
Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation
J Swift, IL Ivanovska, A Buxboim, T Harada, PCDP Dingal, J Pinter, ...
Science 341 (6149), 1240104, 2013
Mesenchymal stem cell perspective: cell biology to clinical progress
MF Pittenger, DE Discher, BM Péault, DG Phinney, JM Hare, AI Caplan
NPJ Regenerative medicine 4 (1), 22, 2019
Substrate compliance versus ligand density in cell on gel responses
A Engler, L Bacakova, C Newman, A Hategan, M Griffin, D Discher
Biophysical journal 86 (1), 617-628, 2004
Bio-inspired, bioengineered and biomimetic drug delivery carriers
JW Yoo, DJ Irvine, DE Discher, S Mitragotri
Nature reviews Drug discovery 10 (7), 521-535, 2011
Mitotic progression following DNA damage enables pattern recognition within micronuclei
SM Harding, JL Benci, J Irianto, DE Discher, AJ Minn, RA Greenberg
Nature 548 (7668), 466-470, 2017
Minimal" Self" peptides that inhibit phagocytic clearance and enhance delivery of nanoparticles
PL Rodriguez, T Harada, DA Christian, DA Pantano, RK Tsai, DE Discher
Science 339 (6122), 971-975, 2013
Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating
AJ Engler, C Carag-Krieger, CP Johnson, M Raab, HY Tang, ...
Journal of cell science 121 (22), 3794-3802, 2008
Physical plasticity of the nucleus in stem cell differentiation
JD Pajerowski, KN Dahl, FL Zhong, PJ Sammak, DE Discher
Proceedings of the National Academy of Sciences 104 (40), 15619-15624, 2007
Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance
MF Berry, AJ Engler, YJ Woo, TJ Pirolli, LT Bish, V Jayasankar, KJ Morine, ...
American Journal of Physiology-Heart and Circulatory Physiology 290 (6 …, 2006
Self-porating polymersomes of PEG–PLA and PEG–PCL: hydrolysis-triggered controlled release vesicles
F Ahmed, DE Discher
Journal of controlled release 96 (1), 37-53, 2004
Polymer vesicles in vivo: correlations with PEG molecular weight
PJ Photos, L Bacakova, B Discher, FS Bates, DE Discher
Journal of Controlled Release 90 (3), 323-334, 2003
Biodegradable polymersomes loaded with both paclitaxel and doxorubicin permeate and shrink tumors, inducing apoptosis in proportion to accumulated drug
F Ahmed, RI Pakunlu, A Brannan, F Bates, T Minko, DE Discher
Journal of Controlled Release 116 (2), 150-158, 2006
Molecular weight dependence of polymersome membrane structure, elasticity, and stability
H Bermudez, AK Brannan, DA Hammer, FS Bates, DE Discher
Macromolecules 35 (21), 8203-8208, 2002
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