| PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome X Dong, D Shen, X Wang, T Dawson, X Li, Q Zhang, X Cheng, Y Zhang, ... Nature communications 1 (1), 38, 2010 | 636 | 2010 |
| Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J CY Chow, Y Zhang, JJ Dowling, N Jin, M Adamska, K Shiga, K Szigeti, ... Nature 448 (7149), 68-72, 2007 | 565 | 2007 |
| VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI (3, 5) P2 in yeast and mouse N Jin, CY Chow, L Liu, SN Zolov, R Bronson, M Davisson, JL Petersen, ... The EMBO journal 27 (24), 3221-3234, 2008 | 278 | 2008 |
| Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3, 5-bisphosphate, results in neurodegeneration in mice Y Zhang, SN Zolov, CY Chow, SG Slutsky, SC Richardson, RC Piper, ... Proceedings of the National Academy of Sciences 104 (44), 17518-17523, 2007 | 247 | 2007 |
| In vivo, Pikfyve generates PI (3, 5) P2, which serves as both a signaling lipid and the major precursor for PI5P SN Zolov, D Bridges, Y Zhang, WW Lee, E Riehle, R Verma, GM Lenk, ... Proceedings of the National Academy of Sciences 109 (43), 17472-17477, 2012 | 239 | 2012 |
| Phosphatidylinositol 3, 5‐bisphosphate: low abundance, high significance AJ McCartney, Y Zhang, LS Weisman BioEssays 36 (1), 52-64, 2014 | 213 | 2014 |
| ROOT HAIR DEFECTIVE4 Encodes a Phosphatidylinositol-4-Phosphate Phosphatase Required for Proper Root Hair Development in Arabidopsis thaliana JM Thole, JEM Vermeer, Y Zhang, TWJ Gadella Jr, E Nielsen The Plant Cell 20 (2), 381-395, 2008 | 186 | 2008 |
| Genetically encoded fluorescent probe to visualize intracellular phosphatidylinositol 3, 5-bisphosphate localization and dynamics X Li, X Wang, X Zhang, M Zhao, WL Tsang, Y Zhang, RGW Yau, ... Proceedings of the National Academy of Sciences 110 (52), 21165-21170, 2013 | 155 | 2013 |
| Targeting cancer metabolism by simultaneously disrupting parallel nutrient access pathways SM Kim, SG Roy, B Chen, TM Nguyen, RJ McMonigle, AN McCracken, ... The Journal of clinical investigation 126 (11), 4088-4102, 2016 | 72 | 2016 |
| Modulation of synaptic function by VAC14, a protein that regulates the phosphoinositides PI (3, 5) P2 and PI (5) P Y Zhang, AJ McCartney, SN Zolov, CJ Ferguson, MH Meisler, MA Sutton, ... The EMBO journal 31 (16), 3442-3456, 2012 | 70 | 2012 |
| Insulin stimulates phosphatidylinositol 3-phosphate production via the activation of Rab5 IJ Lodhi, D Bridges, SH Chiang, Y Zhang, A Cheng, LM Geletka, ... Molecular biology of the cell 19 (7), 2718-2728, 2008 | 69 | 2008 |
| Activity-dependent PI (3, 5) P2 synthesis controls AMPA receptor trafficking during synaptic depression AJ McCartney, SN Zolov, EJ Kauffman, Y Zhang, BS Strunk, LS Weisman, ... Proceedings of the National Academy of Sciences 111 (45), E4896-E4905, 2014 | 66 | 2014 |
| DENN domain-containing protein FAM45A regulates the homeostasis of late/multivesicular endosomes J Zhang, K Zhang, L Qi, Q Hu, Z Shen, B Liu, J Deng, C Zhang, Y Zhang Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1866 (5), 916-929, 2019 | 21 | 2019 |
| Involvement of proapoptotic genes in autophagic cell death induced by irradiation J Song, X Zhao, Y Feng, S Xu, Y Zhang, L Wei Cell Death Discovery 3 (1), 1-9, 2017 | 8 | 2017 |
| Phosphatidylinositol (3, 5)-bisphosphate machinery regulates neurite thickness through neuron-specific endosomal protein NSG1/NEEP21 L Qi, C Sun, S Sun, A Li, Q Hu, Y Liu, Y Zhang Journal of Biological Chemistry 299 (1), 2023 | 1 | 2023 |
Clement Y ChowAssistant Professor, Department of Human Genetics, University of UtahVerified email at genetics.utah.edu
