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Clara L. Kielkopf
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A structural basis for recognition of A T and T A base pairs in the minor groove of B-DNA
CL Kielkopf, S White, JW Szewczyk, JM Turner, EE Baird, PB Dervan, ...
Science 282 (5386), 111-115, 1998
4471998
Structural basis for G• C recognition in the DNA minor groove
CL Kielkopf, EE Baird, PB Dervan, DC Rees
Nature structural biology 5 (2), 104-109, 1998
3451998
U2AF homology motifs: protein recognition in the RRM world
CL Kielkopf, S Lcke, MR Green
Genes & development 18 (13), 1513-1526, 2004
3012004
Bradford assay for determining protein concentration
CL Kielkopf, W Bauer, IL Urbatsch
Cold Spring Harbor Protocols 2020 (4), pdb. prot102269, 2020
2692020
A novel peptide recognition mode revealed by the X-ray structure of a core U2AF35/U2AF65 heterodimer
CL Kielkopf, NA Rodionova, MR Green, SK Burley
Cell 106 (5), 595-605, 2001
2452001
Structural basis for polypyrimidine tract recognition by the essential pre-mRNA splicing factor U2AF65
EA Sickmier, KE Frato, H Shen, SR Paranawithana, MR Green, ...
Molecular cell 23 (1), 49-59, 2006
2122006
Structure of a photoactive rhodium complex intercalated into DNA
CL Kielkopf, KE Erkkila, BP Hudson, JK Barton, DC Rees
Nature structural biology 7 (2), 117-121, 2000
1672000
U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing
T Okeyo-Owuor, BS White, R Chatrikhi, DR Mohan, S Kim, M Griffith, ...
Leukemia 29 (4), 909-917, 2015
1392015
Conformational flexibility of B-DNA at 0.74 resolution: d (CCAGTACTGG) 2
CL Kielkopf, S Ding, P Kuhn, DC Rees
Journal of molecular biology 296 (3), 787-801, 2000
1232000
Structural effects of DNA sequence on T A recognition by hydroxypyrrole/pyrrole pairs in the minor groove
CL Kielkopf, RE Bremer, S White, JW Szewczyk, JM Turner, EE Baird, ...
Journal of molecular biology 295 (3), 557-567, 2000
1182000
Structural basis for NADH/NAD+ redox sensing by a Rex family repressor
KJ McLaughlin, CM Strain-Damerell, K Xie, D Brekasis, AS Soares, ...
Molecular cell 38 (4), 563-575, 2010
1172010
X-ray structure of a Rex-family repressor/NADH complex insights into the mechanism of redox sensing
EA Sickmier, D Brekasis, S Paranawithana, JB Bonanno, MSB Paget, ...
Structure 13 (1), 43-54, 2005
1052005
Wild-type U2AF1 antagonizes the splicing program characteristic of U2AF1-mutant tumors and is required for cell survival
DL Fei, H Motowski, R Chatrikhi, S Prasad, J Yu, S Gao, CL Kielkopf, ...
PLoS Genetics 12 (10), e1006384, 2016
972016
Multiple U2AF65 binding sites within SF3b155: thermodynamic and spectroscopic characterization of protein–protein interactions among pre-mRNA splicing factors
KR Thickman, MC Swenson, JM Kabogo, Z Gryczynski, CL Kielkopf
Journal of molecular biology 356 (3), 664-683, 2006
752006
An extended U2AF65–RNA-binding domain recognizes the 3′ splice site signal
AA Agrawal, E Salsi, R Chatrikhi, S Henderson, JL Jenkins, MR Green, ...
Nature communications 7 (1), 10950, 2016
702016
Staufen1 dimerizes through a conserved motif and a degenerate dsRNA-binding domain to promote mRNA decay
ML Gleghorn, C Gong, CL Kielkopf, LE Maquat
Nature structural & molecular biology 20 (4), 515-524, 2013
692013
Major phosphorylation of SF1 on adjacent Ser‐Pro motifs enhances interaction with U2AF65
V Manceau, M Swenson, JP Le Caer, A Sobel, CL Kielkopf, A Maucuer
The FEBS journal 273 (3), 577-587, 2006
692006
Splicing factor mutations in myelodysplasias: insights from spliceosome structures
JL Jenkins, CL Kielkopf
Trends in Genetics 33 (5), 336-348, 2017
602017
X-ray Structures of Threonine Aldolase Complexes:  Structural Basis of Substrate Recognition,
CL Kielkopf, SK Burley
Biochemistry 41 (39), 11711-11720, 2002
602002
Cancer-relevant splicing factor CAPERα engages the essential splicing factor SF3b155 in a specific ternary complex
S Loerch, A Maucuer, V Manceau, MR Green, CL Kielkopf
Journal of Biological Chemistry 289 (25), 17325-17337, 2014
552014
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