| Interactions between hydrophobic and ionic solutes in aqueous guanidinium chloride and urea solutions: lessons for protein denaturation mechanism EP O'Brien, RI Dima, B Brooks, D Thirumalai Journal of the American Chemical Society 129 (23), 7346-7353, 2007 | 418 | 2007 |
| Cotranslational protein folding inside the ribosome exit tunnel OB Nilsson, R Hedman, J Marino, S Wickles, L Bischoff, M Johansson, ... Cell reports 12 (10), 1533-1540, 2015 | 291 | 2015 |
| Theoretical perspectives on protein folding D Thirumalai, EP O'Brien, G Morrison, C Hyeon Annual review of biophysics 39 (1), 159-183, 2010 | 216 | 2010 |
| Effects of denaturants and osmolytes on proteins are accurately predicted by the molecular transfer model EP O'Brien, G Ziv, G Haran, BR Brooks, D Thirumalai Proceedings of the National Academy of Sciences 105 (36), 13403-13408, 2008 | 196 | 2008 |
| Profiling Ssb-nascent chain interactions reveals principles of Hsp70-assisted folding K Döring, N Ahmed, T Riemer, HG Suresh, Y Vainshtein, M Habich, ... Cell 170 (2), 298-311. e20, 2017 | 172 | 2017 |
| Does SARS-CoV-2 bind to human ACE2 more strongly than does SARS-CoV? HL Nguyen, PD Lan, NQ Thai, DA Nissley, EP O’Brien, MS Li The Journal of Physical Chemistry B 124 (34), 7336-7347, 2020 | 145 | 2020 |
| Effects of pH on proteins: predictions for ensemble and single-molecule pulling experiments EP O’Brien, BR Brooks, D Thirumalai Journal of the American Chemical Society 134 (2), 979-987, 2012 | 133 | 2012 |
| Understanding the influence of codon translation rates on cotranslational protein folding EP O’Brien, P Ciryam, M Vendruscolo, CM Dobson Accounts of chemical research 47 (5), 1536-1544, 2014 | 115 | 2014 |
| In vivo translation rates can substantially delay the cotranslational folding of the Escherichia coli cytosolic proteome P Ciryam, RI Morimoto, M Vendruscolo, CM Dobson, EP O’Brien Proceedings of the National Academy of Sciences 110 (2), E132-E140, 2013 | 111 | 2013 |
| Prediction of variable translation rate effects on cotranslational protein folding EP O'brien, M Vendruscolo, CM Dobson Nature communications 3 (1), 868, 2012 | 107 | 2012 |
| Thermodynamic perspective on the dock− lock growth mechanism of amyloid fibrils EP O’Brien, Y Okamoto, JE Straub, BR Brooks, D Thirumalai The Journal of Physical Chemistry B 113 (43), 14421-14430, 2009 | 105 | 2009 |
| How accurate are polymer models in the analysis of Förster resonance energy transfer experiments on proteins? EP O’Brien, G Morrison, BR Brooks, D Thirumalai The Journal of chemical physics 130 (12), 2009 | 105 | 2009 |
| New scenarios of protein folding can occur on the ribosome EP O’Brien, J Christodoulou, M Vendruscolo, CM Dobson Journal of the American Chemical Society 133 (3), 513-526, 2011 | 103 | 2011 |
| Trigger factor slows co-translational folding through kinetic trapping while sterically protecting the nascent chain from aberrant cytosolic interactions EP O’Brien, J Christodoulou, M Vendruscolo, CM Dobson Journal of the American Chemical Society 134 (26), 10920-10932, 2012 | 89 | 2012 |
| Transient tertiary structure formation within the ribosome exit port EP O’Brien, STD Hsu, J Christodoulou, M Vendruscolo, CM Dobson Journal of the American Chemical Society 132 (47), 16928-16937, 2010 | 89 | 2010 |
| Kinetic modelling indicates that fast-translating codons can coordinate cotranslational protein folding by avoiding misfolded intermediates EP O’Brien, M Vendruscolo, CM Dobson Nature communications 5 (1), 2988, 2014 | 88 | 2014 |
| Collapse kinetics and chevron plots from simulations of denaturant-dependent folding of globular proteins Z Liu, G Reddy, EP O’Brien, D Thirumalai Proceedings of the National Academy of Sciences 108 (19), 7787-7792, 2011 | 78 | 2011 |
| Screening donor blood for malaria by polymerase chain reaction T Van Be, PN Tran, L Van Hien, E O'Brien, GE Morris Transactions of the Royal Society of Tropical Medicine and Hygiene 89 (1), 44-47, 1995 | 77 | 1995 |
| Effect of finite size on cooperativity and rates of protein folding M Kouza, MS Li, EP O'Brien, CK Hu, D Thirumalai The Journal of Physical Chemistry A 110 (2), 671-676, 2006 | 74 | 2006 |
| Kinetic and structural comparison of a protein’s cotranslational folding and refolding pathways AJ Samelson, E Bolin, SM Costello, AK Sharma, EP O’Brien, S Marqusee Science Advances 4 (5), eaas9098, 2018 | 68 | 2018 |
Devarajan ThirumalaiUniversity of Texas at AustinVerified email at umd.edu
