Erik Ladewig
Erik Ladewig
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Clonal evolution of glioblastoma under therapy
J Wang, E Cazzato, E Ladewig, V Frattini, DIS Rosenbloom, S Zairis, ...
Nature genetics 48 (7), 768-776, 2016
Comparative analysis of the transcriptome across distant species
MB Gerstein, J Rozowsky, KK Yan, D Wang, C Cheng, JB Brown, ...
Nature 512 (7515), 445-448, 2014
Spatiotemporal genomic architecture informs precision oncology in glioblastoma
JK Lee, J Wang, JK Sa, E Ladewig, HO Lee, IH Lee, HJ Kang, ...
Nature genetics 49 (4), 594-599, 2017
Discovery of hundreds of mirtrons in mouse and human small RNA data
E Ladewig, K Okamura, AS Flynt, JO Westholm, EC Lai
Genome research 22 (9), 1634-1645, 2012
Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors
N Vasan, P Razavi, JL Johnson, H Shao, H Shah, A Antoine, E Ladewig, ...
Science 366 (6466), 714-723, 2019
Pervasive mutations of JAK-STAT pathway genes in classical Hodgkin lymphoma
E Tiacci, E Ladewig, G Schiavoni, A Penson, E Fortini, V Pettirossi, ...
Blood, The Journal of the American Society of Hematology 131 (22), 2454-2465, 2018
ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer
G Xu, S Chhangawala, E Cocco, P Razavi, Y Cai, JE Otto, L Ferrando, ...
Nature genetics 52 (2), 198-207, 2020
Analysis of nearly one thousand mammalian mirtrons reveals novel features of dicer substrates
J Wen, E Ladewig, S Shenker, J Mohammed, EC Lai
PLoS computational biology 11 (9), e1004441, 2015
Common and distinct patterns of terminal modifications to mirtrons and canonical microRNAs
JO Westholm, E Ladewig, K Okamura, N Robine, EC Lai
Rna 18 (2), 177-192, 2012
FOXA1 mutations reveal distinct chromatin profiles and influence therapeutic response in breast cancer
A Arruabarrena-Aristorena, JLV Maag, S Kittane, Y Cai, WR Karthaus, ...
Cancer cell 38 (4), 534-550. e9, 2020
Functional small RNAs are generated from select miRNA hairpin loops in flies and mammals
K Okamura, E Ladewig, L Zhou, EC Lai
Genes & development 27 (7), 778-792, 2013
Diversity of miRNAs, siRNAs, and piRNAs across 25 Drosophila cell lines
J Wen, J Mohammed, D Bortolamiol-Becet, H Tsai, N Robine, ...
Genome research 24 (7), 1236-1250, 2014
Nuclear proximity of Mtr4 to RNA exosome restricts DNA mutational asymmetry
J Lim, PK Giri, D Kazadi, B Laffleur, W Zhang, V Grinstein, E Pefanis, ...
Cell 169 (3), 523-537. e15, 2017
Genetic mechanisms of HLA-I loss and immune escape in diffuse large B cell lymphoma
M Fangazio, E Ladewig, K Gomez, L Garcia-Ibanez, R Kumar, ...
Proceedings of the National Academy of Sciences 118 (22), e2104504118, 2021
Distinct genomic profile and specific targeted drug responses in adult cerebellar glioblastoma
HJ Cho, J Zhao, SW Jung, E Ladewig, DS Kong, YL Suh, Y Lee, D Kim, ...
Neuro-oncology 21 (1), 47-58, 2019
Genomic Alterations in PIK3CA-Mutated Breast Cancer Result in mTORC1 Activation and Limit the Sensitivity to PI3Kα Inhibitors
Y Cai, G Xu, F Wu, F Michelini, C Chan, X Qu, P Selenica, E Ladewig, ...
Cancer research 81 (9), 2470-2480, 2021
New recurrently mutated genes in classical hodgkin lymphoma revealed by whole-exome sequencing of microdissected tumor cells
E Tiacci, A Penson, G Schiavoni, E Ladewig, E Fortini, Y Wang, ...
Blood 128 (22), 1088, 2016
Reprogramming tumor-associated macrophages to outcompete endovascular endothelial progenitor cells and suppress tumor neoangiogenesis
MH Do, W Shi, L Ji, E Ladewig, X Zhang, RM Srivastava, KJ Capistrano, ...
Immunity 56 (11), 2555-2569. e5, 2023
The oncogenic PI3K-induced transcriptomic landscape reveals key functions in splicing and gene expression regulation
E Ladewig, F Michelini, K Jhaveri, P Castel, J Carmona, L Fairchild, ...
Cancer research 82 (12), 2269-2280, 2022
Abstract NG16: Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors
N Vasan, P Razavi, JL Johnson, H Shao, H Shah, A Antoine, E Ladewig, ...
Cancer Research 80 (16_Supplement), NG16-NG16, 2020
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