jean-christophe bourdon
jean-christophe bourdon
Director of Research, University of Dundee, UK
Verified email at - Homepage
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p53 isoforms can regulate p53 transcriptional activity
JC Bourdon, K Fernandes, F Murray-Zmijewski, G Liu, A Diot, ...
Genes & development 19 (18), 2122-2137, 2005
Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity
DP Xirodimas, MK Saville, JC Bourdon, RT Hay, DP Lane
Cell 118 (1), 83-97, 2004
p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress
F Murray-Zmijewski, DP Lane, JC Bourdon
Cell Death & Differentiation 13 (6), 962-972, 2006
Uncovering the role of p53 splice variants in human malignancy: a clinical perspective
S Surget, MP Khoury, JC Bourdon
OncoTargets and therapy, 57-68, 2013
p53 isoforms Δ133p53 and p53β are endogenous regulators of replicative cellular senescence
K Fujita, AM Mondal, I Horikawa, GH Nguyen, K Kumamoto, JJ Sohn, ...
Nature cell biology 11 (9), 1135-1142, 2009
p53 and its isoforms in cancer
JC Bourdon
British journal of cancer 97 (3), 277-282, 2007
p53 acts as a safeguard of translational control by regulating fibrillarin and rRNA methylation in cancer
V Marcel, SE Ghayad, S Belin, G Therizols, AP Morel, E Solano-Gonzàlez, ...
Cancer cell 24 (3), 318-330, 2013
The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor
GJ Bates, SM Nicol, BJ Wilson, AMF Jacobs, JC Bourdon, J Wardrop, ...
The EMBO journal 24 (3), 543-553, 2005
The isoforms of the p53 protein
MP Khoury, JC Bourdon
Cold Spring Harbor perspectives in biology 2 (3), a000927, 2010
p53 isoforms: an intracellular microprocessor?
MP Khoury, JC Bourdon
Genes & cancer 2 (4), 453-465, 2011
Biological functions of p53 isoforms through evolution: lessons from animal and cellular models
V Marcel, ML Dichtel-Danjoy, C Sagne, H Hafsi, D Ma, S Ortiz-Cuaran, ...
Cell Death & Differentiation 18 (12), 1815-1824, 2011
DNA polymerase θ up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability
F Lemée, V Bergoglio, A Fernandez-Vidal, A Machado-Silva, MJ Pillaire, ...
Proceedings of the National Academy of Sciences 107 (30), 13390-13395, 2010
Further characterisation of the p53 responsive element–identification of new candidate genes for trans-activation by p53
JC Bourdon, V Degui-Chambon, JC Lelong, P Dessen, P May, B Debuire, ...
Oncogene 14 (1), 85-94, 1997
p53 isoform Δ113p53 is a p53 target gene that antagonizes p53 apoptotic activity via BclxL activation in zebrafish
J Chen, SM Ng, C Chang, Z Zhang, JC Bourdon, DP Lane, J Peng
Genes & development 23 (3), 278-290, 2009
p53 isoforms: key regulators of the cell fate decision
SM Joruiz, JC Bourdon
Cold Spring Harbor perspectives in medicine 6 (8), a026039, 2016
Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo
MK Saville, A Sparks, DP Xirodimas, J Wardrop, LF Stevenson, ...
Journal of Biological Chemistry 279 (40), 42169-42181, 2004
Δ160p53 is a novel N-terminal p53 isoform encoded by Δ133p53 transcript
V Marcel, S Perrier, M Aoubala, S Ageorges, MJ Groves, A Diot, ...
FEBS letters 584 (21), 4463-4468, 2010
Human and mouse Fas (APO-1/CD95) death receptor genes each contain a p53-responsive element that is activated by p53 mutants unable to induce apoptosis
D Munsch, R Watanabe-Fukunaga, JC Bourdon, S Nagata, E May, ...
Journal of Biological Chemistry 275 (6), 3867-3872, 2000
Scotin, a novel p53-inducible proapoptotic protein located in the ER and the nuclear membrane
JC Bourdon, J Renzing, PL Robertson, KN Fernandes, DP Lane
The Journal of cell biology 158 (2), 235-246, 2002
p53 directly transactivates Δ133p53α, regulating cell fate outcome in response to DNA damage
M Aoubala, F Murray-Zmijewski, MP Khoury, K Fernandes, S Perrier, ...
Cell Death & Differentiation 18 (2), 248-258, 2011
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