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David J. Loane
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The far-reaching scope of neuroinflammation after traumatic brain injury
DW Simon, MJ McGeachy, H Bayır, RSB Clark, DJ Loane, PM Kochanek
Nature Reviews Neurology 13 (3), 171-191, 2017
9242017
Role of microglia in neurotrauma
DJ Loane, KR Byrnes
Neurotherapeutics 7 (4), 366-377, 2010
7692010
Neuroinflammation after traumatic brain injury: opportunities for therapeutic intervention
A Kumar, DJ Loane
Brain, behavior, and immunity 26 (8), 1191-1201, 2012
7492012
Microglia in the TBI brain: the good, the bad, and the dysregulated
DJ Loane, A Kumar
Experimental neurology 275, 316-327, 2016
7072016
Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies
DJ Loane, AI Faden
Trends in pharmacological sciences 31 (12), 596-604, 2010
6202010
Progressive neurodegeneration after experimental brain trauma: association with chronic microglial activation
DJ Loane, A Kumar, BA Stoica, R Cabatbat, AI Faden
Journal of Neuropathology & Experimental Neurology 73 (1), 14-29, 2014
5122014
Microglial/macrophage polarization dynamics following traumatic brain injury
A Kumar, DM Alvarez-Croda, BA Stoica, AI Faden, DJ Loane
Journal of neurotrauma 33 (19), 1732-1750, 2016
3272016
Progressive inflammation‐mediated neurodegeneration after traumatic brain or spinal cord injury
AI Faden, J Wu, BA Stoica, DJ Loane
British journal of pharmacology 173 (4), 681-691, 2016
2992016
Chronic neurodegeneration after traumatic brain injury: Alzheimer disease, chronic traumatic encephalopathy, or persistent neuroinflammation?
AI Faden, DJ Loane
Neurotherapeutics 12 (1), 143-150, 2015
2792015
Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states
A Kumar, BA Stoica, B Sabirzhanov, MP Burns, AI Faden, DJ Loane
Neurobiology of aging 34 (5), 1397-1411, 2013
2792013
Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury
DJ Loane, A Pocivavsek, CEH Moussa, R Thompson, Y Matsuoka, ...
Nature medicine 15 (4), 377-379, 2009
2722009
Microglial-derived microparticles mediate neuroinflammation after traumatic brain injury
A Kumar, BA Stoica, DJ Loane, M Yang, G Abulwerdi, N Khan, A Kumar, ...
Journal of neuroinflammation 14, 1-17, 2017
2692017
Sexual dimorphism in the inflammatory response to traumatic brain injury
S Villapol, DJ Loane, MP Burns
Glia 65 (9), 1423-1438, 2017
2672017
Microglial depletion with CSF1R inhibitor during chronic phase of experimental traumatic brain injury reduces neurodegeneration and neurological deficits
RJ Henry, RM Ritzel, JP Barrett, SJ Doran, Y Jiao, JB Leach, GL Szeto, ...
Journal of Neuroscience 40 (14), 2960-2974, 2020
2292020
Delayed mGluR5 activation limits neuroinflammation and neurodegeneration after traumatic brain injury
KR Byrnes, DJ Loane, BA Stoica, J Zhang, AI Faden
Journal of neuroinflammation 9, 1-15, 2012
1902012
NOX2 drives M1-like microglial/macrophage activation and neurodegeneration following experimental traumatic brain injury
A Kumar, JP Barrett, DM Alvarez-Croda, BA Stoica, AI Faden, DJ Loane
Brain, behavior, and immunity 58, 291-309, 2016
1892016
Metabotropic glutamate receptor 5 activation inhibits microglial associated inflammation and neurotoxicity
KR Byrnes, B Stoica, DJ Loane, A Riccio, MI Davis, AI Faden
Glia 57 (5), 550-560, 2009
1892009
Eicosapentaenoic acid confers neuroprotection in the amyloid-β challenged aged hippocampus
AM Lynch, DJ Loane, AM Minogue, RM Clarke, D Kilroy, RE Nally, ...
Neurobiology of aging 28 (6), 845-855, 2007
1792007
Late exercise reduces neuroinflammation and cognitive dysfunction after traumatic brain injury
CS Piao, BA Stoica, J Wu, B Sabirzhanov, Z Zhao, R Cabatbat, DJ Loane, ...
Neurobiology of disease 54, 252-263, 2013
1652013
Downregulation of miR-23a and miR-27a following experimental traumatic brain injury induces neuronal cell death through activation of proapoptotic Bcl-2 proteins
B Sabirzhanov, Z Zhao, BA Stoica, DJ Loane, J Wu, C Borroto, SG Dorsey, ...
Journal of Neuroscience 34 (30), 10055-10071, 2014
1642014
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