| The multi-factorial nature of clinical multidrug resistance in cancer YG Assaraf, A Brozovic, AC Gonçalves, D Jurkovicova, A Linē, ... Drug Resistance Updates 46, 100645, 2019 | 303 | 2019 |
| (+/−)‐Naringenin as large conductance Ca2+‐activated K+ (BKCa) channel opener in vascular smooth muscle cells S Saponara, L Testai, D Iozzi, E Martinotti, A Martelli, S Chericoni, ... British journal of pharmacology 149 (8), 1013-1021, 2006 | 142 | 2006 |
| Effects of quercetin and rutin on vascular preparations: a comparison between mechanical and electrophysiological phenomena. F Fusi, S Saponara, F Pessina, B Gorelli, G Sgaragli European journal of nutrition 42 (1), 2003 | 97 | 2003 |
| Quercetin as a novel activator of L‐type Ca2+ channels in rat tail artery smooth muscle cells S Saponara, G Sgaragli, F Fusi British journal of pharmacology 135 (7), 1819-1827, 2002 | 92 | 2002 |
| Development and pharmacological characterization of selective blockers of 2-arachidonoyl glycerol degradation with efficacy in rodent models of multiple sclerosis and pain M Brindisi, S Maramai, S Gemma, S Brogi, A Grillo, L Di Cesare Mannelli, ... Journal of medicinal chemistry 59 (6), 2612-2632, 2016 | 72 | 2016 |
| Folate-targeted liposomal nitrooxy-doxorubicin: An effective tool against P-glycoprotein-positive and folate receptor-positive tumors E Gazzano, B Rolando, K Chegaev, IC Salaroglio, J Kopecka, I Pedrini, ... Journal of controlled release 270, 37-52, 2018 | 64 | 2018 |
| The beneficial health effects of flavonoids on the cardiovascular system: Focus on K+ channels F Fusi, A Trezza, M Tramaglino, G Sgaragli, S Saponara, O Spiga Pharmacological Research 152, 104625, 2020 | 59 | 2020 |
| 2,5‐Di‐t‐butyl‐1,4‐benzohydroquinone (BHQ) inhibits vascular L‐type Ca2+ channel via superoxide anion generation F Fusi, S Saponara, H Gagov, G Sgaragli British journal of pharmacology 133 (7), 988-996, 2001 | 58 | 2001 |
| Repurposing old drugs to fight multidrug resistant cancers J Dinić, T Efferth, AT García-Sosa, J Grahovac, JM Padrón, I Pajeva, ... Drug Resistance Updates 52, 100713, 2020 | 56 | 2020 |
| A specific taurine recognition site in the rabbit brain is responsible for taurine effects on thermoregulation M Frosini, C Sesti, S Saponara, L Ricci, M Valoti, M Palmi, F Machetti, ... British journal of pharmacology 139 (3), 487-494, 2003 | 54 | 2003 |
| Characterization of voltage‐gated calcium currents in freshly isolated smooth muscle cells from rat tail main artery GV Petkov, F Fusi, S Saponara, HS Gagov, GP Sgaragli, KK Boev Acta physiologica scandinavica 173 (3), 257-265, 2001 | 52 | 2001 |
| Targeting Dopamine D3 and Serotonin 5-HT1A and 5-HT2A Receptors for Developing Effective Antipsychotics: Synthesis, Biological Characterization, and … M Brindisi, S Butini, S Franceschini, S Brogi, F Trotta, S Ros, A Cagnotto, ... Journal of medicinal chemistry 57 (22), 9578-9597, 2014 | 49 | 2014 |
| The flavonoid scaffold as a template for the design of modulators of the vascular Cav1.2 channels S Saponara, E Carosati, P Mugnai, G Sgaragli, F Fusi British journal of pharmacology 164 (6), 1684-1697, 2011 | 48 | 2011 |
| The surge of flavonoids as novel, fine regulators of cardiovascular Cav channels F Fusi, O Spiga, A Trezza, G Sgaragli, S Saponara European journal of pharmacology 796, 158-174, 2017 | 46 | 2017 |
| Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: Further structure–activity relationships, in vivo studies, and preliminary toxicity profiling S Gemma, C Camodeca, S Sanna Coccone, BP Joshi, M Bernetti, ... Journal of medicinal chemistry 55 (15), 6948-6967, 2012 | 46 | 2012 |
| 3, 5‐Dibenzoyl‐4‐(3‐phenoxyphenyl)‐1, 4‐dihydro‐2, 6‐dimethylpyridine (DP7) as a new multidrug resistance reverting agent devoid of effects on vascular smooth muscle contractility S Saponara, M Kawase, A Shah, N Motohashi, J Molnar, K Ugocsai, ... British journal of pharmacology 141 (3), 415-422, 2004 | 43 | 2004 |
| Hypoxia as a driver of resistance to immunotherapy J Kopecka, IC Salaroglio, E Perez-Ruiz, AB Sarmento-Ribeiro, ... Drug Resistance Updates, 100787, 2021 | 41 | 2021 |
| Mechanism of osthole inhibition of vascular Cav1. 2 current F Fusi, G Sgaragli, NM Cuong, S Saponara European Journal of Pharmacology 680 (1-3), 22-27, 2012 | 41 | 2012 |
| Quercetin antagonism of Bay K 8644 effects on rat tail artery L-type Ca2+ channels S Saponara, G Sgaragli, F Fusi European journal of pharmacology 598 (1-3), 75-80, 2008 | 41 | 2008 |
| Quercetin antagonism of Bay K 8644 effects on rat tail artery L-type Ca2+ channels S Saponara, G Sgaragli, F Fusi European journal of pharmacology 598 (1-3), 75-80, 2008 | 41 | 2008 |
