Esther C.Y. Woon
Cited by
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The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases
R Chowdhury, KK Yeoh, YM Tian, L Hillringhaus, EA Bagg, NR Rose, ...
EMBO reports 12 (5), 463-469, 2011
A safe lithium mimetic for bipolar disorder
N Singh, AC Halliday, JM Thomas, OV Kuznetsova, R Baldwin, ...
Nature communications 4 (1), 1332, 2013
Selective inhibitors of the JMJD2 histone demethylases: combined nondenaturing mass spectrometric screening and crystallographic approaches
NR Rose, ECY Woon, GL Kingham, ONF King, J Mecinovic, IJ Clifton, ...
Journal of medicinal chemistry 53 (4), 1810-1818, 2010
Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases
NR Rose, ECY Woon, A Tumber, LJ Walport, R Chowdhury, XS Li, ...
Journal of medicinal chemistry 55 (14), 6639-6643, 2012
N6-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5
S Zou, JDW Toh, KHQ Wong, YG Gao, W Hong, ECY Woon
Scientific reports 6 (1), 25677, 2016
Inhibition of histone demethylases by 4-carboxy-2, 2′-bipyridyl compounds
KH Chang, ONF King, A Tumber, ECY Woon, TD Heightman, ...
ChemMedChem 6 (5), 759, 2011
A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor of N 6-methyladenosine demethylase FTO
JDW Toh, L Sun, LZM Lau, J Tan, JJA Low, CWQ Tang, EJY Cheong, ...
Chemical science 6 (1), 112-122, 2015
Doxorubicin-loaded cell-derived nanovesicles: An alternative targeted approach for anti-tumor therapy
WJ Goh, CK Lee, S Zou, ECY Woon, B Czarny, G Pastorin
International journal of nanomedicine, 2759-2767, 2017
Dynamic combinatorial chemistry employing boronic acids/boronate esters leads to potent oxygenase inhibitors
M Demetriades, IKH Leung, R Chowdhury, MC Chan, MA McDonough, ...
Angewandte Chemie International Edition 51 (27), 6672-6675, 2012
Linking of 2‐oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylases
ECY Woon, A Tumber, A Kawamura, L Hillringhaus, W Ge, NR Rose, ...
Angewandte Chemie 124 (7), 1663-1666, 2012
Poly (ADP-ribose) polymerase inhibition-where now?
ECY Woon, MD Threadgill
Current medicinal chemistry 12 (20), 2373-2392, 2005
5-Nitroisocoumarins from tandem Castro–Stephens coupling—6-endo-dig cyclisation of 2-iodo-3-nitrobenzoic acid and arylethynes and ring-closure of methyl 2-alkynyl-3 …
ECY Woon, A Dhami, MF Mahon, MD Threadgill
Tetrahedron 62 (20), 4829-4837, 2006
Dynamic combinatorial mass spectrometry leads to inhibitors of a 2-oxoglutarate-dependent nucleic acid demethylase
ECY Woon, M Demetriades, EAL Bagg, WS Aik, SM Krylova, JHY Ma, ...
Journal of medicinal chemistry 55 (5), 2173-2184, 2012
5-Benzamidoisoquinolin-1-ones and 5-(ω-carboxyalkyl) isoquinolin-1-ones as isoform-selective inhibitors of poly (ADP-ribose) polymerase 2 (PARP-2)
PT Sunderland, ECY Woon, A Dhami, AB Bergin, MF Mahon, PJ Wood, ...
Journal of medicinal chemistry 54 (7), 2049-2059, 2011
Observations on the deprotection of pinanediol and pinacol boronate esters via fluorinated intermediates
SR Inglis, ECY Woon, AL Thompson, CJ Schofield
The Journal of Organic Chemistry 75 (2), 468-471, 2010
Structure-Guided Design of Cell Wall Biosynthesis Inhibitors That Overcome β-Lactam Resistance in Staphylococcus aureus (MRSA)
C Contreras-Martel, A Amoroso, ECY Woon, A Zervosen, S Inglis, ...
ACS chemical biology 6 (9), 943-951, 2011
Synthesis and Evaluation of 3-(Dihydroxyboryl)benzoic Acids as d,d-Carboxypeptidase R39 Inhibitors
SR Inglis, A Zervosen, ECY Woon, T Gerards, N Teller, DS Fischer, ...
Journal of medicinal chemistry 52 (19), 6097-6106, 2009
Hepatic FTO expression is increased in NASH and its silencing attenuates palmitic acid-induced lipotoxicity
A Lim, J Zhou, RA Sinha, BK Singh, S Ghosh, KH Lim, PKH Chow, ...
Biochemical and biophysical research communications 479 (3), 476-481, 2016
Exploration of the nicotinamide-binding site of the tankyrases, identifying 3-arylisoquinolin-1-ones as potent and selective inhibitors in vitro
HA Paine, A Nathubhai, ECY Woon, PT Sunderland, PJ Wood, MF Mahon, ...
Bioorganic & Medicinal Chemistry 23 (17), 5891-5908, 2015
Dual-action inhibitors of HIF prolyl hydroxylases that induce binding of a second iron ion
KK Yeoh, MC Chan, A Thalhammer, M Demetriades, R Chowdhury, ...
Organic & biomolecular chemistry 11 (5), 732-745, 2013
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