Does SARS-CoV-2 bind to human ACE2 more strongly than does SARS-CoV? HL Nguyen, PD Lan, NQ Thai, DA Nissley, EP O’Brien, MS Li The Journal of Physical Chemistry B 124 (34), 7336-7347, 2020 | 132 | 2020 |
Accurate prediction of cellular co-translational folding indicates proteins can switch from post-to co-translational folding DA Nissley, AK Sharma, N Ahmed, UA Friedrich, G Kramer, B Bukau, ... Nature communications 7 (1), 10341, 2016 | 54 | 2016 |
Timing is everything: unifying codon translation rates and nascent proteome behavior DA Nissley, EP O’Brien Journal of the American Chemical Society 136 (52), 17892-17898, 2014 | 52 | 2014 |
Domain topology, stability, and translation speed determine mechanical force generation on the ribosome SE Leininger, F Trovato, DA Nissley, EP O’Brien Proceedings of the National Academy of Sciences 116 (12), 5523-5532, 2019 | 51 | 2019 |
Current structure predictors are not learning the physics of protein folding C Outeiral, DA Nissley, CM Deane Bioinformatics 38 (7), 1881-1887, 2022 | 50 | 2022 |
Electrostatic interactions govern extreme nascent protein ejection times from ribosomes and can delay ribosome recycling DA Nissley, QV Vu, F Trovato, N Ahmed, Y Jiang, MS Li, EP O’Brien Journal of the American Chemical Society 142 (13), 6103-6110, 2020 | 36 | 2020 |
Origins of the mechanochemical coupling of peptide bond formation to protein synthesis B Fritch, A Kosolapov, P Hudson, DA Nissley, HL Woodcock, C Deutsch, ... Journal of the American Chemical Society 140 (15), 5077-5087, 2018 | 36 | 2018 |
Universal protein misfolding intermediates can bypass the proteostasis network and remain soluble and less functional DA Nissley, Y Jiang, F Trovato, I Sitarik, KB Narayan, P To, Y Xia, ... Nature communications 13 (1), 3081, 2022 | 28 | 2022 |
Structural origins of FRET-observed nascent chain compaction on the ribosome DA Nissley, EP O’Brien The Journal of Physical Chemistry B 122 (43), 9927-9937, 2018 | 22 | 2018 |
Electrostatic interactions explain the higher binding affinity of the CR3022 antibody for SARS-CoV-2 than the 4A8 antibody H Nguyen, PD Lan, DA Nissley, EP O’Brien, MS Li The Journal of Physical Chemistry B 125 (27), 7368-7379, 2021 | 20 | 2021 |
Cocktail of REGN antibodies binds more strongly to SARS-CoV-2 than its components, but the Omicron variant reduces its neutralizing ability H Nguyen, PD Lan, DA Nissley, EP O’Brien, MS Li The Journal of Physical Chemistry B 126 (15), 2812-2823, 2022 | 13 | 2022 |
Altered co-translational processing plays a role in Huntington's pathogenesis—a hypothesis DA Nissley, EP O'Brien Frontiers in Molecular Neuroscience 9, 54, 2016 | 10 | 2016 |
Computationally profiling peptide: MHC recognition by T-cell receptors and T-cell receptor-mimetic antibodies MIJ Raybould, DA Nissley, S Kumar, CM Deane Frontiers in Immunology 13, 1080596, 2023 | 5 | 2023 |
Subpopulations of soluble, misfolded proteins commonly bypass chaperones: How it happens at the molecular level R Halder, DA Nissley, I Sitarik, EP O’Brien bioRxiv, 2021.08. 18.456736, 2021 | 5 | 2021 |
Current protein structure predictors do not produce meaningful folding pathways C Outeiral, DA Nissley, CM Deane BioRxiv, 2021.09. 20.461137, 2021 | 4 | 2021 |
Ribosome occupancy profiles are conserved between structurally and evolutionarily related yeast domains DA Nissley, A Carbery, M Chonofsky, CM Deane Bioinformatics 37 (13), 1853-1859, 2021 | 4 | 2021 |
Spatially selective formation of hydrocarbon, fluorocarbon, and hydroxyl-terminated monolayers on a microelectrode array KM Cook, DA Nissley, GS Ferguson Langmuir 29 (23), 6779-6783, 2013 | 4 | 2013 |
How soluble misfolded proteins bypass chaperones at the molecular level R Halder, DA Nissley, I Sitarik, Y Jiang, Y Rao, QV Vu, MS Li, J Pritchard, ... Nature communications 14 (1), 3689, 2023 | 2 | 2023 |
Synonymous mutations can alter protein dimerization through localized interface misfolding involving self-entanglements PD Lan, DA Nissley, I Sitarik, QV Vu, Y Jiang, P To, Y Xia, SD Fried, MS Li, ... Journal of Molecular Biology, 168487, 2024 | 1 | 2024 |
Is Posttranslational Folding More Efficient Than Refolding from a Denatured State: A Computational Study QV Vu, DA Nissley, Y Jiang, EP O’Brien, MS Li The Journal of Physical Chemistry B 127 (21), 4761-4774, 2023 | 1 | 2023 |