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Anh TN Nguyen
Anh TN Nguyen
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Year
Structure of the adenosine-bound human adenosine A1 receptor–Gi complex
CJ Draper-Joyce, M Khoshouei, DM Thal, YL Liang, ATN Nguyen, ...
Nature 558 (7711), 559-563, 2018
3282018
Structure of the adenosine A1 receptor reveals the basis for subtype selectivity
A Glukhova, DM Thal, AT Nguyen, EA Vecchio, M Jörg, PJ Scammells, ...
Cell 168 (5), 867-877. e13, 2017
2842017
Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia
CJ Draper-Joyce, R Bhola, J Wang, A Bhattarai, ATN Nguyen, ...
Nature 597 (7877), 571-576, 2021
1012021
Extracellular loop 2 of the adenosine A1 receptor has a key role in orthosteric ligand affinity and agonist efficacy
ATN Nguyen, JA Baltos, T Thomas, TD Nguyen, LL Muñoz, KJ Gregory, ...
Molecular Pharmacology 90 (6), 703-714, 2016
592016
New paradigms in adenosine receptor pharmacology: allostery, oligomerization and biased agonism
EA Vecchio, JA Baltos, ATN Nguyen, A Christopoulos, PJ White, LT May
British journal of pharmacology 175 (21), 4036-4046, 2018
542018
Structural Basis for Binding of Allosteric Drug Leads in the Adenosine A1 Receptor
Y Miao, A Bhattarai, ATN Nguyen, A Christopoulos, LT May
Scientific reports 8 (1), 16836, 2018
532018
AMP-Activated Protein Kinase (AMPK) Activation by Benzofurans and Coumestans Isolated from Erythrina abyssinica
PH Nguyen, TNA Nguyen, TT Dao, HW Kang, DT Ndinteh, JT Mbafor, ...
Journal of natural products 73 (4), 598-602, 2010
522010
Role of the second extracellular loop of the adenosine A1 receptor on allosteric modulator binding, signaling, and cooperativity
ATN Nguyen, EA Vecchio, T Thomas, TD Nguyen, L Aurelio, ...
Molecular pharmacology 90 (6), 715-725, 2016
512016
Influenza A (H1N1) neuraminidase inhibitors from Vitis amurensis
TNA Nguyen, TT Dao, BT Tung, H Choi, E Kim, J Park, SIL Lim, WK Oh
Food chemistry 124 (2), 437-443, 2011
492011
Structure-activity analysis of biased agonism at the human adenosine A3 receptor
JA Baltos, S Paoletta, ATN Nguyen, KJ Gregory, DK Tosh, ...
Molecular pharmacology 90 (1), 12-22, 2016
432016
Prenylated pterocarpans as bacterial neuraminidase inhibitors
PH Nguyen, TNA Nguyen, KW Kang, DT Ndinteh, JT Mbafor, YR Kim, ...
Bioorganic & medicinal chemistry 18 (9), 3335-3344, 2010
402010
A Structure–Activity Relationship Study of Bitopic N6-Substituted Adenosine Derivatives as Biased Adenosine A1 Receptor Agonists
L Aurelio, JA Baltos, L Ford, ATN Nguyen, M Jorg, SM Devine, C Valant, ...
Journal of medicinal chemistry 61 (5), 2087-2103, 2018
282018
Novel Irreversible Agonists Acting at the A1 Adenosine Receptor
M Jorg, A Glukhova, A Abdul-Ridha, EA Vecchio, ATN Nguyen, ...
Journal of Medicinal Chemistry 59 (24), 11182-11194, 2016
272016
α1A-Adrenoceptors activate mTOR signalling and glucose uptake in cardiomyocytes
M Sato, BA Evans, AL Sandström, LY Chia, S Mukaida, B San Thai, ...
Biochemical Pharmacology 148, 27-40, 2018
232018
The application of artificial intelligence to accelerate G protein‐coupled receptor drug discovery
ATN Nguyen, DTN Nguyen, HY Koh, J Toskov, W MacLean, A Xu, ...
British Journal of Pharmacology, 2023
152023
Development and Application of Subtype-Selective Fluorescent Antagonists for the Study of the Human Adenosine A1 Receptor in Living Cells
E Comeo, P Trinh, AT Nguyen, CJ Nowell, ND Kindon, M Soave, ...
Journal of Medicinal Chemistry 64 (10), 6670-6695, 2021
82021
Structure-based virtual screening discovers potent and selective adenosine A1 receptor antagonists
P Matricon, ATN Nguyen, DD Vo, JA Baltos, M Jaiteh, A Luttens, ...
European Journal of Medicinal Chemistry 257, 115419, 2023
62023
Small molecule allosteric modulation of the adenosine A1 receptor
ATN Nguyen, QL Tran, JA Baltos, SM McNeill, DTN Nguyen, LT May
Frontiers in Endocrinology 14, 1184360, 2023
52023
Targeting G protein‐coupled receptors for heart failure treatment
BS Thai, LY Chia, ATN Nguyen, C Qin, RH Ritchie, DS Hutchinson, ...
British Journal of Pharmacology, 2023
42023
Examining the Role of the Linker in Bitopic N6-Substituted Adenosine Derivatives Acting as Biased Adenosine A1 Receptor Agonists
JK Awalt, ATN Nguyen, TJ Fyfe, BS Thai, PJ White, A Christopoulos, ...
Journal of Medicinal Chemistry 65 (13), 9076-9095, 2022
22022
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