Oxetanes as versatile elements in drug discovery and synthesis JA Burkhard, G Wuitschik, M Rogers‐Evans, K Müller, EM Carreira Angewandte Chemie International Edition 49 (48), 9052-9067, 2010 | 426 | 2010 |
Oxetanes in drug discovery: structural and synthetic insights G Wuitschik, EM Carreira, B Wagner, H Fischer, I Parrilla, F Schuler, ... Journal of medicinal chemistry 53 (8), 3227-3246, 2010 | 411 | 2010 |
Oxetanes as promising modules in drug discovery G Wuitschik, M Rogers‐Evans, K Müller, H Fischer, B Wagner, F Schuler, ... Angewandte Chemie International Edition 45 (46), 7736-7739, 2006 | 278 | 2006 |
Spirocyclic oxetanes: synthesis and properties G Wuitschik, M Rogers-Evans, A Buckl, M Bernasconi, M Marki, T Godel, ... Angewandte Chemie 120 (24), 4588, 2008 | 234 | 2008 |
Piperazic acid-containing natural products: isolation, biological relevance and total synthesis AJ Oelke, DJ France, T Hofmann, G Wuitschik, SV Ley Natural Product Reports 28 (8), 1445-1471, 2011 | 97 | 2011 |
Synthesis and stability of oxetane analogs of thalidomide and lenalidomide JA Burkhard, G Wuitschik, JM Plancher, M Rogers-Evans, EM Carreira Organic letters 15 (17), 4312-4315, 2013 | 94 | 2013 |
Oxetane als vielseitige Bausteine in der Wirkstoff‐Forschung und Synthese JA Burkhard, G Wuitschik, M Rogers‐Evans, K Müller, EM Carreira Angewandte Chemie 122 (48), 9236-9251, 2010 | 86 | 2010 |
A Ru-Catalyzed Tandem Alkyne−Enone Coupling/Michael Addition: Synthesis of 4-Methylene-2,6-cis-tetrahydropyrans BM Trost, H Yang, G Wuitschik Organic Letters 7 (21), 4761-4764, 2005 | 72 | 2005 |
Total synthesis of chloptosin AJ Oelke, DJ France, T Hofmann, G Wuitschik, SV Ley Angewandte Chemie International Edition 49 (35), 6139-6142, 2010 | 57 | 2010 |
What can reaction databases teach us about Buchwald–Hartwig cross-couplings? M Fitzner, G Wuitschik, RJ Koller, JM Adam, T Schindler, JL Reymond Chemical science 11 (48), 13085-13093, 2020 | 52 | 2020 |
Total synthesis of chloptosin: A dimeric cyclohexapeptide AJ Oelke, F Antonietti, L Bertone, PB Cranwell, DJ France, RJM Goss, ... Chemistry–A European Journal 17 (15), 4183-4194, 2011 | 52 | 2011 |
Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learning DF Nippa, K Atz, R Hohler, AT Müller, A Marx, C Bartelmus, G Wuitschik, ... Nature Chemistry 16 (2), 239-248, 2024 | 43 | 2024 |
Machine learning C–N couplings: Obstacles for a general-purpose reaction yield prediction M Fitzner, G Wuitschik, R Koller, JM Adam, T Schindler ACS omega 8 (3), 3017-3025, 2023 | 32 | 2023 |
Using data analysis to evaluate and compare chemical syntheses D Kaiser, J Yang, G Wuitschik Organic Process Research & Development 22 (9), 1222-1235, 2018 | 25 | 2018 |
A Robust, Recyclable Resin for Decagram Scale Resolution of (±)‐Mefloquine and Other Chiral N‐Heterocycles I Kreituss, KY Chen, SH Eitel, JM Adam, G Wuitschik, A Fettes, JW Bode Angewandte Chemie International Edition 55 (4), 1553-1556, 2016 | 24 | 2016 |
The search for tricyanomethane (cyanoform) D Šišak, LB McCusker, A Buckl, G Wuitschik, YL Wu, WB Schweizer, ... Chemistry–A European Journal 16 (24), 7224-7230, 2010 | 21 | 2010 |
Oxetanes in drug discovery G Wuitschik ETH Zurich, 2008 | 17 | 2008 |
Tricyanomethane and its salts with nitrogen bases: A correction of sixteen reports K Banert, M Hagedorn Synlett 30 (12), 1427-1430, 2019 | 12 | 2019 |
Efficient Manufacturing Process for the Selective Estrogen Receptor Degrader GDC-9545 (Giredestrant) via a Crystallization-Driven Diastereoselective Pictet–Spengler Condensation J Xu, CK Chung, A McClory, KA Mack, ME Dalziel, A Fettes, K Clagg, ... Organic Process Research & Development 26 (3), 568-582, 2021 | 8 | 2021 |
Accounting for different reactivities of sulfinate and thiosulfate salts in regioselective azetidine coupling via C–H sulfenylation of indoles MAE Al-Saedy, ACMA Nassoy, JPA Harrity Synlett 29 (03), 349-353, 2018 | 7 | 2018 |