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Douglas Jacobsen
Douglas Jacobsen
Graduate Student Instructor, University of Michigan
Verified email at umich.edu
Title
Cited by
Cited by
Year
Briefly bound to activate: transient binding of a second catalytic magnesium activates the structure and dynamics of CDK2 kinase for catalysis
ZQ Bao, DM Jacobsen, MA Young
Structure 19 (5), 675-690, 2011
1082011
Price to be paid for two-metal catalysis: magnesium ions that accelerate chemistry unavoidably limit product release from a protein kinase
DM Jacobsen, ZQ Bao, P O’Brien, CL Brooks III, MA Young
Journal of the American Chemical Society 134 (37), 15357-15370, 2012
732012
ChromoScan: a scan statistic application for identifying chromosomal regions in genomic studies
YV Sun, DM Jacobsen, SLR Kardia
Bioinformatics 22 (23), 2945-2947, 2006
232006
Disruption of magnesium regulation in the crab Cancer productus exposed to chlorinated seawater
G Roesijadi, DM Jacobsen, JR Bridge, EA Crecelius
Marine Environmental Research 2 (1), 71-84, 1979
121979
Fast implementation of a scan statistic for identifying chromosomal patterns of genome wide association studies
YV Sun, DM Jacobsen, ST Turner, E Boerwinkle, SLR Kardia
Computational statistics & data analysis 53 (5), 1794-1801, 2009
102009
KGraph: a system for visualizing and evaluating complex genetic associations
RJ Kelly, DM Jacobsen, YV Sun, JA Smith, SLR Kardia
Bioinformatics 23 (2), 249-251, 2007
102007
Brooks, r., Charles L; Young, MA, Price to Be Paid for Two-Metal Catalysis: Magnesium Ions That Accelerate Chemistry Unavoidably Limit Product Release from a Protein Kinase
DM Jacobsen, ZQ Bao, P O'Brien
J Am Chem Soc 134, 15357-15370, 2012
52012
Allosteric Regulation of Protein Kinase Enzymes via an Electrostatic Switch that Modulates Active Site Dynamics
MA Young, DM Jacobsen, ZQ Bao
Biophysical Journal 106 (2), 651a, 2014
2014
Dual Role of Magnesium Ions in Active pCDK2/Cyclin: Essential Activator of Kinase Activity and Partial Inhibitor of Product Release
DM Jacobsen, ZQ Bao, CL Brooks, MA Young
Biophysical Journal 102 (3), 271a, 2012
2012
An investigation of the roles of magnesium ions in the catalytic cycle of the protein kinase CDK2: A molecular link between allosteric activation and catalytic activity
DM Jacobsen
University of Michigan, 2012
2012
A fast implementation of scan statistic for identifying chromosomal patterns of genome wide association studies
YV Sun, DM Jacobsen, ST Turner, KR Bailey, E Boerwinkle, SLR Kardia
GENETIC EPIDEMIOLOGY 31 (6), 612-613, 2007
2007
KGraph: Visualizing and evaluating complex genetic associations
RJ Kelly, DM Jacobsen, YV Sun, JA Smith, SLR Kardia
GENETIC EPIDEMIOLOGY 31 (5), 478-478, 2007
2007
Wednesday, February 19, 2014 651a
MA Young, DM Jacobsen, ZQ Bao
A price to be paid for two-metal catalysis: Magnesium ions that accelerate chemistry unavoidably limit product release from CDK2 kinase.
DM Jacobsen, ZQ Bao, P O’Brien, CLB III, MA Young
Supplemental Information Briefly Bound to Activate: Transient Binding of a Second Catalytic Magnesium Activates the Structure and Dynamics of CDK2 Kinase for Catalysis
ZQ Bao, DM Jacobsen, MA Young
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