Ralf Bartenschlager
Ralf Bartenschlager
Professor of Molecular Virology, Heidelberg University
Verified email at - Homepage
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Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line
V Lohmann, F Korner, JO Koch, U Herian, L Theilmann, R Bartenschlager
Science 285 (5424), 110-113, 1999
Production of infectious hepatitis C virus in tissue culture from a cloned viral genome
T Wakita, T Pietschmann, T Kato, T Date, M Miyamoto, Z Zhao, K Murthy, ...
Nature medicine 11 (7), 791-796, 2005
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
E Meylan, J Curran, K Hofmann, D Moradpour, M Binder, ...
Nature 437 (7062), 1167-1172, 2005
The lipid droplet is an important organelle for hepatitis C virus production
Y Miyanari, K Atsuzawa, N Usuda, K Watashi, T Hishiki, M Zayas, ...
Nature cell biology 9 (9), 1089-1097, 2007
Composition and three-dimensional architecture of the dengue virus replication and assembly sites
S Welsch, S Miller, I Romero-Brey, A Merz, CKE Bleck, P Walther, ...
Cell host & microbe 5 (4), 365-375, 2009
Replication of hepatitis C virus
R Bartenschlager, V Lohmann
Journal of general virology 81 (7), 1631-1648, 2000
Structures and distributions of SARS-CoV-2 spike proteins on intact virions
Z Ke, J Oton, K Qu, M Cortese, V Zila, L McKeane, T Nakane, J Zivanov, ...
Nature 588 (7838), 498-502, 2020
Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras
T Pietschmann, A Kaul, G Koutsoudakis, A Shavinskaya, S Kallis, ...
Proceedings of the National Academy of Sciences 103 (19), 7408-7413, 2006
Identification of the hepatitis C virus RNA replication complex in Huh-7 cells harboring subgenomic replicons
R Gosert, D Egger, V Lohmann, R Bartenschlager, HE Blum, K Bienz, ...
Journal of virology 77 (9), 5487-5492, 2003
Biochemical properties of hepatitis C virus NS5B RNA-dependent RNA polymerase and identification of amino acid sequence motifs essential for enzymatic activity
V Lohmann, F Körner, U Herian, R Bartenschlager
Journal of virology 71 (11), 8416-8428, 1997
Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations
N Krieger, V Lohmann, R Bartenschlager
Journal of virology 75 (10), 4614-4624, 2001
Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctions
R Bartenschlager, L Ahlborn-Laake, J Mous, H Jacobsen
Journal of virology 67 (7), 3835-3844, 1993
SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography
S Klein, M Cortese, SL Winter, M Wachsmuth-Melm, CJ Neufeldt, ...
Nature communications 11 (1), 5885, 2020
Essential role of domain III of nonstructural protein 5A for hepatitis C virus infectious particle assembly
N Appel, M Zayas, S Miller, J Krijnse-Locker, T Schaller, P Friebe, S Kallis, ...
PLoS pathogens 4 (3), e1000035, 2008
Host-directed therapies for bacterial and viral infections
SHE Kaufmann, A Dorhoi, RS Hotchkiss, R Bartenschlager
Nature reviews Drug discovery 17 (1), 35-56, 2018
Mutations in hepatitis C virus RNAs conferring cell culture adaptation
V Lohmann, F Körner, A Dobierzewska, R Bartenschlager
Journal of virology 75 (3), 1437-1449, 2001
The non-structural protein 4A of dengue virus is an integral membrane protein inducing membrane alterations in a 2K-regulated manner
S Miller, S Kastner, J Krijnse-Locker, S Buhler, R Bartenschlager
Journal of Biological Chemistry 282 (12), 8873-8882, 2007
Three-dimensional architecture and biogenesis of membrane structures associated with hepatitis C virus replication
I Romero-Brey, A Merz, A Chiramel, JY Lee, P Chlanda, U Haselman, ...
PLoS pathogens 8 (12), e1003056, 2012
Assembly of infectious hepatitis C virus particles
R Bartenschlager, F Penin, V Lohmann, P André
Trends in microbiology 19 (2), 95-103, 2011
Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment
S Reiss, I Rebhan, P Backes, I Romero-Brey, H Erfle, P Matula, L Kaderali, ...
Cell host & microbe 9 (1), 32-45, 2011
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