Thomas Zichner

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Jan KorbelHead of Data Science, EMBL & Bridging Research Division Head, DKFZ, HeidelbergVerified email at embl.de
Tobias RauschEuropean Molecular Biology LaboratoryVerified email at embl.de
Marc StreitProfessor for Visual Data Science @ Johannes Kepler University LinzVerified email at jku.at
Holger Stitzdatavisyn GmbH, AustriaVerified email at datavisyn.io
Eileen E FurlongGroup Leader, Head of Dept.: European Molecular Biology LaboratoryVerified email at embl.de
David GarfieldGenentechVerified email at gene.com
Enrico CannavoGenentechVerified email at gene.com
Wolfgang HuberEMBL - European Molecular Biology LaboratoryVerified email at embl.org
Raeka AiyarStanford Genome Technology Center, Stanford UniversityVerified email at stanford.edu
Julien GagneurProfessor, TUM, MunichVerified email at in.tum.de
Gregoire PauGenentech, Université de RennesVerified email at gene.com
Paul Theodor PylDepartment of Laboratory Medicine, National Bioinformatics Infrastructure Sweden, Science for LifeVerified email at scilifelab.se
Nicolas DelhommeResearcher, UPSC, Swedish University of Agricultural SciencesVerified email at slu.se
Sebastian BöckerProfessor für Bioinformatik, FSU JenaVerified email at uni-jena.de
Falk HüffnerTomTomVerified email at tomtom.com
Franziska HufskyRNA Bioinformatics and High Throughput Analysis, Friedrich Schiller University JenaVerified email at uni-jena.de
Pierre KhoueiryBoehringer-IngelheimVerified email at boehringer-ingelheim.com
Katarína FurmanováMasaryk UniversityVerified email at mail.muni.cz
Alexander LexAssociate Professor, SCI Institute, Kahlert School of Computing, University of UtahVerified email at sci.utah.edu
Sebastian M. WaszakAssistant Professor, Laboratory of Computational Neuro-Oncology, EPFLVerified email at epfl.ch

Thomas Zichner

Distinguished Scientist, Boehringer Ingelheim RCV, Austria

Verified email at embl.de

Computational biology Structural variation Next-generation sequencing


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An integrated map of structural variation in 2,504 human genomes PH Sudmant, T Rausch, EJ Gardner, RE Handsaker, A Abyzov, ... Nature 526 (7571), 75-81, 2015	2503	2015
DELLY: structural variant discovery by integrated paired-end and split-read analysis T Rausch, T Zichner, A Schlattl, AM Stütz, V Benes, JO Korbel Bioinformatics 28 (18), i333-i339, 2012	2222	2012
The whole-genome landscape of medulloblastoma subtypes PA Northcott, I Buchhalter, AS Morrissy, V Hovestadt, J Weischenfeldt, ... Nature 547 (7663), 311-317, 2017	1045	2017
Subgroup-specific structural variation across 1,000 medulloblastoma genomes PA Northcott, DJH Shih, J Peacock, L Garzia, A Sorana Morrissy, ... Nature 488 (7409), 49-56, 2012	999	2012
Dissecting the genomic complexity underlying medulloblastoma DTW Jones, N Jäger, M Kool, T Zichner, B Hutter, M Sultan, YJ Cho, ... Nature 488 (7409), 100-105, 2012	981	2012
Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations T Rausch, DTW Jones, M Zapatka, AM Stütz, T Zichner, J Weischenfeldt, ... Cell 148 (1), 59-71, 2012	967	2012
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma DTW Jones, B Hutter, N Jäger, A Korshunov, M Kool, HJ Warnatz, ... Nature genetics 45 (8), 927-932, 2013	843	2013
Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma PA Northcott, C Lee, T Zichner, AM Stütz, S Erkek, D Kawauchi, DJH Shih, ... Nature 511 (7510), 428-434, 2014	719	2014
Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines W Huang, A Massouras, Y Inoue, J Peiffer, M Ràmia, AM Tarone, ... Genome research 24 (7), 1193-1208, 2014	664	2014
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ... Nature 506 (7489), 445-450, 2014	663	2014
The genomic and transcriptomic landscape of a HeLa cell line JJM Landry, PT Pyl, T Rausch, T Zichner, MM Tekkedil, AM Stütz, A Jauch, ... G3: Genes, Genomes, Genetics 3 (8), 1213-1224, 2013	636	2013
Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking J Weischenfeldt, T Dubash, AP Drainas, BR Mardin, Y Chen, AM Stütz, ... Nature genetics 49 (1), 65-74, 2017	403	2017
Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer J Weischenfeldt, R Simon, L Feuerbach, K Schlangen, D Weichenhan, ... Cancer cell 23 (2), 159-170, 2013	401	2013
Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort SM Waszak, PA Northcott, I Buchhalter, GW Robinson, C Sutter, ... The Lancet Oncology 19 (6), 785-798, 2018	389	2018
Shadow enhancers are pervasive features of developmental regulatory networks E Cannavò, P Khoueiry, DA Garfield, P Geeleher, T Zichner, ... Current Biology 26 (1), 38-51, 2016	271	2016
Genomics and drug profiling of fatal TCF3-HLF−positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options U Fischer, M Forster, A Rinaldi, T Risch, S Sungalee, HJ Warnatz, ... Nature genetics 47 (9), 1020-1029, 2015	261	2015
Recurrent MET fusion genes represent a drug target in pediatric glioblastoma Nature medicine 22 (11), 1314-1320, 2016	188	2016
Identifying the unknowns by aligning fragmentation trees F Rasche, K Scheubert, F Hufsky, T Zichner, M Kai, A Svatoš, S Böcker Analytical chemistry 84 (7), 3417-3426, 2012	139	2012
Impact of genomic structural variation in Drosophila melanogaster based on population-scale sequencing T Zichner, DA Garfield, T Rausch, AM Stütz, E Cannavó, M Braun, ... Genome research 23 (3), 568-579, 2013	95	2013
Algorithm engineering for color-coding with applications to signaling pathway detection F Hüffner, S Wernicke, T Zichner Algorithmica 52, 114-132, 2008	95	2008

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