| PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome X Dong, D Shen, X Wang, T Dawson, X Li, Q Zhang, X Cheng, Y Zhang, ... Nature communications 1 (1), 38, 2010 | 638 | 2010 |
| TPC proteins are phosphoinositide-activated sodium-selective ion channels in endosomes and lysosomes X Wang, X Zhang, X Dong, M Samie, X Li, X Cheng, A Goschka, D Shen, ... Cell 151 (2), 372-383, 2012 | 589 | 2012 |
| Lipid storage disorders block lysosomal trafficking by inhibiting a TRP channel and lysosomal calcium release D Shen, X Wang, X Li, X Zhang, Z Yao, S Dibble, X Dong, T Yu, ... Nature communications 3 (1), 731, 2012 | 488 | 2012 |
| A TRP channel in the lysosome regulates large particle phagocytosis via focal exocytosis M Samie, X Wang, X Zhang, A Goschka, X Li, X Cheng, E Gregg, M Azar, ... Developmental cell 26 (5), 511-524, 2013 | 286 | 2013 |
| TRP channels of intracellular membranes XP Dong, X Wang, H Xu Journal of neurochemistry 113 (2), 313-328, 2010 | 201 | 2010 |
| Genetically encoded fluorescent probe to visualize intracellular phosphatidylinositol 3, 5-bisphosphate localization and dynamics X Li, X Wang, X Zhang, M Zhao, WL Tsang, Y Zhang, RGW Yau, ... Proceedings of the National Academy of Sciences 110 (52), 21165-21170, 2013 | 155 | 2013 |
| Activating mutations of the TRPML1 channel revealed by proline-scanning mutagenesis X Dong, X Wang, D Shen, S Chen, M Liu, Y Wang, E Mills, X Cheng, ... Journal of biological chemistry 284 (46), 32040-32052, 2009 | 141 | 2009 |
| The intracellular Ca2+ channel MCOLN1 is required for sarcolemma repair to prevent muscular dystrophy X Cheng, X Zhang, Q Gao, M Ali Samie, M Azar, WL Tsang, L Dong, ... Nature medicine 20 (10), 1187-1192, 2014 | 127 | 2014 |
| LRRK2 inhibitors induce reversible changes in nonhuman primate lungs without measurable pulmonary deficits MAS Baptista, K Merchant, T Barrett, S Bhargava, DK Bryce, JM Ellis, ... Science translational medicine 12 (540), eaav0820, 2020 | 93 | 2020 |
| Pairing phosphoinositides with calcium ions in endolysosomal dynamics: phosphoinositides control the direction and specificity of membrane trafficking by regulating the … D Shen, X Wang, H Xu Bioessays 33 (6), 448-457, 2011 | 67 | 2011 |
| Understanding LRRK2 kinase activity in preclinical models and human subjects through quantitative analysis of LRRK2 and pT73 Rab10 X Wang, E Negrou, MT Maloney, VV Bondar, SV Andrews, M Montalban, ... Scientific Reports 11 (1), 12900, 2021 | 38 | 2021 |
| Novel Na+-Selective Channels in the Lysosome X Wang, X Zhang, X Dong, M Samie, X Li, D Shen, X Cheng, A Goschka, ... Biophysical Journal 102 (3), 105a, 2012 | | 2012 |
| Activating Mutations Reveal a Role of TRPML1 in Lysosomal Exocytosis X Wang, X Dong, D Shen, H Xu Biophysical Journal 98 (3), 340a-341a, 2010 | | 2010 |
| Activation Mutations of the TRPML1 Channel Revealed by Proline Scanning Mutagenesis X Wang, X Dong, S Chen, D Shen, M Liu, E Mills, X Cheng, M Delling, ... Biophysical Journal 96 (3), 266a, 2009 | | 2009 |
