Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice G Sapparapu, E Fernandez, N Kose, B Cao, JM Fox, RG Bombardi, ... Nature 540 (7633), 443-447, 2016 | 410 | 2016 |
A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection N Kose, JM Fox, G Sapparapu, R Bombardi, RN Tennekoon, AD De Silva, ... Science immunology 4 (35), eaaw6647, 2019 | 196 | 2019 |
Cross-neutralizing and protective human antibody specificities to poxvirus infections I Gilchuk, P Gilchuk, G Sapparapu, R Lampley, V Singh, N Kose, DL Blum, ... Cell 167 (3), 684-694. e9, 2016 | 185 | 2016 |
Cross-reactive and potent neutralizing antibody responses in human survivors of natural ebolavirus infection AI Flyak, X Shen, CD Murin, HL Turner, JA David, ML Fusco, R Lampley, ... Cell 164 (3), 392-405, 2016 | 178 | 2016 |
Mechanism of human antibody-mediated neutralization of Marburg virus AI Flyak, PA Ilinykh, CD Murin, T Garron, X Shen, ML Fusco, T Hashiguchi, ... Cell 160 (5), 893-903, 2015 | 165 | 2015 |
Isolation and characterization of broad and ultrapotent human monoclonal antibodies with therapeutic activity against chikungunya virus SA Smith, LA Silva, JM Fox, AI Flyak, N Kose, G Sapparapu, ... Cell host & microbe 18 (1), 86-95, 2015 | 154 | 2015 |
A human antibody against Zika virus crosslinks the E protein to prevent infection SS Hasan, A Miller, G Sapparapu, E Fernandez, T Klose, F Long, ... Nature communications 8 (1), 14722, 2017 | 151 | 2017 |
Human rotavirus VP6-specific antibodies mediate intracellular neutralization by binding to a quaternary structure in the transcriptional pore MS Aiyegbo, G Sapparapu, BW Spiller, IM Eli, DR Williams, R Kim, ... PloS one 8 (5), e61101, 2013 | 93 | 2013 |
Broadly neutralizing antibodies from human survivors target a conserved site in the Ebola virus glycoprotein HR2–MPER region AI Flyak, N Kuzmina, CD Murin, C Bryan, E Davidson, P Gilchuk, ... Nature microbiology 3 (6), 670-677, 2018 | 76 | 2018 |
H7N9 influenza virus neutralizing antibodies that possess few somatic mutations NJ Thornburg, H Zhang, S Bangaru, G Sapparapu, N Kose, RM Lampley, ... The Journal of clinical investigation 126 (4), 1482-1494, 2016 | 70 | 2016 |
Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity F Long, RH Fong, SK Austin, Z Chen, T Klose, A Fokine, Y Liu, J Porta, ... Proceedings of the National Academy of Sciences 112 (45), 13898-13903, 2015 | 63 | 2015 |
Mapping the human memory B cell and serum neutralizing antibody responses to dengue virus serotype 4 infection and vaccination UK Nivarthi, N Kose, G Sapparapu, D Widman, E Gallichotte, JM Pfaff, ... Journal of virology 91 (5), 10.1128/jvi. 02041-16, 2017 | 62 | 2017 |
Dengue virus prM-specific human monoclonal antibodies with virus replication-enhancing properties recognize a single immunodominant antigenic site SA Smith, UK Nivarthi, R de Alwis, N Kose, G Sapparapu, R Bombardi, ... Journal of virology 90 (2), 780-789, 2016 | 59 | 2016 |
Structural basis for norovirus neutralization by an HBGA blocking human IgA antibody S Shanker, R Czakó, G Sapparapu, G Alvarado, M Viskovska, B Sankaran, ... Proceedings of the National Academy of Sciences 113 (40), E5830-E5837, 2016 | 52 | 2016 |
Exceptional amyloid β peptide hydrolyzing activity of nonphysiological immunoglobulin variable domain scaffolds H Taguchi, S Planque, G Sapparapu, S Boivin, M Hara, Y Nishiyama, ... Journal of Biological Chemistry 283 (52), 36724-36733, 2008 | 47 | 2008 |
Monoclonal Antibodies Against the Staphylococcus aureus Bicomponent Leukotoxin AB Isolated Following Invasive Human Infection Reveal Diverse Binding and … IP Thomsen, G Sapparapu, DBA James, JE Cassat, M Nagarsheth, ... The Journal of infectious diseases 215 (7), 1124-1131, 2017 | 43 | 2017 |
Mouse and human monoclonal antibodies protect against infection by multiple genotypes of Japanese encephalitis virus E Fernandez, N Kose, MA Edeling, J Adhikari, G Sapparapu, SM Lazarte, ... MBio 9 (1), 10.1128/mbio. 00008-18, 2018 | 38 | 2018 |
Human antibodies that neutralize respiratory droplet transmissible H5N1 influenza viruses NJ Thornburg, DP Nannemann, DL Blum, JA Belser, TM Tumpey, ... The Journal of clinical investigation 123 (10), 4405-4409, 2013 | 35 | 2013 |
Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth JR Willis, G Sapparapu, S Murrell, JP Julien, V Singh, HG King, Y Xia, ... The Journal of clinical investigation 125 (6), 2523-2531, 2015 | 34 | 2015 |
Frequent use of the IgA isotype in human B cells encoding potent norovirus-specific monoclonal antibodies that block HBGA binding G Sapparapu, R Czakó, G Alvarado, S Shanker, BVV Prasad, RL Atmar, ... PLoS Pathogens 12 (6), e1005719, 2016 | 32 | 2016 |