Oliver N. F. King
Oliver N. F. King
Data Analysis Scientist - Machine Vision, Diamond Light Source, UK
Verified email at - Homepage
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The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases
R Chowdhury, KK Yeoh, YM Tian, L Hillringhaus, EA Bagg, NR Rose, ...
EMBO reports 12 (5), 463-469, 2011
Large-scale structural analysis of the classical human protein tyrosine phosphatome
AJ Barr, E Ugochukwu, WH Lee, ONF King, P Filippakopoulos, I Alfano, ...
Cell 136 (2), 352-363, 2009
Inhibition of 2-oxoglutarate dependent oxygenases
NR Rose, MA McDonough, ONF King, A Kawamura, CJ Schofield
Chemical Society Reviews 40 (8), 4364-4397, 2011
Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors
ONF King, XS Li, M Sakurai, A Kawamura, NR Rose, SS Ng, AM Quinn, ...
PloS one 5 (11), e15535, 2010
Specific CLK inhibitors from a novel chemotype for regulation of alternative splicing
O Fedorov, K Huber, A Eisenreich, P Filippakopoulos, O King, AN Bullock, ...
Chemistry & biology 18 (1), 67-76, 2011
Selective inhibitors of the JMJD2 histone demethylases: combined nondenaturing mass spectrometric screening and crystallographic approaches
NR Rose, ECY Woon, GL Kingham, ONF King, J Mecinovic, IJ Clifton, ...
Journal of medicinal chemistry 53 (4), 1810-1818, 2010
5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation
RJ Hopkinson, A Tumber, C Yapp, R Chowdhury, WS Aik, KH Che, XS Li, ...
Chemical science 4 (8), 3110-3117, 2013
Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases
NR Rose, ECY Woon, A Tumber, LJ Walport, R Chowdhury, XS Li, ...
Journal of medicinal chemistry 55 (14), 6639-6643, 2012
Highly selective inhibition of histone demethylases by de novo macrocyclic peptides
A Kawamura, M Münzel, T Kojima, C Yapp, B Bhushan, Y Goto, A Tumber, ...
Nature communications 8 (1), 14773, 2017
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities
D Rotili, S Tomassi, M Conte, R Benedetti, M Tortorici, G Ciossani, ...
Journal of medicinal chemistry 57 (1), 42-55, 2014
Inhibition of histone demethylases by 4-carboxy-2, 2′-bipyridyl compounds
KH Chang, ONF King, A Tumber, ECY Woon, TD Heightman, ...
ChemMedChem 6 (5), 759, 2011
Development of homogeneous luminescence assays for histone demethylase catalysis and binding
A Kawamura, A Tumber, NR Rose, ONF King, M Daniel, U Oppermann, ...
Analytical biochemistry 404 (1), 86-93, 2010
A prominent β-hairpin structure in the winged-helix domain of RECQ1 is required for DNA unwinding and oligomer formation
B Lucic, Y Zhang, O King, R Mendoza-Maldonado, M Berti, FH Niesen, ...
Nucleic acids research 39 (5), 1703-1717, 2011
Discovery of ML324, a JMJD2 demethylase inhibitor with demonstrated antiviral activity
G Rai, A Kawamura, A Tumber, Y Liang, JL Vogel, JH Arbuckle, NR Rose, ...
Probe Reports from the NIH Molecular Libraries Program [Internet], 2013
The Cryptosporidium parvum Kinome
JD Artz, AK Wernimont, A Allali-Hassani, Y Zhao, M Amani, YH Lin, ...
BMC genomics 12, 1-20, 2011
Probe reports from the NIH molecular libraries program
G Rai, A Kawamura, A Tumber, Y Liang, JL Vogel, JH Arbuckle, NR Rose, ...
National Center for Biotechnology Information, 2010
Non-competitive cyclic peptides for targeting enzyme–substrate complexes
TE McAllister, TL Yeh, MI Abboud, IKH Leung, ES Hookway, ONF King, ...
Chemical Science 9 (20), 4569-4578, 2018
A massively multi-scale approach to characterizing tissue architecture by synchrotron micro-CT applied to the human placenta
WM Tun, G Poologasundarampillai, H Bischof, G Nye, ONF King, ...
Journal of The Royal Society Interface 18 (179), 20210140, 2021
Beamline K11 DIAD: A new instrument for dual imaging and diffraction at Diamond Light Source
C Reinhard, M Drakopoulos, SI Ahmed, H Deyhle, A James, ...
Journal of Synchrotron Radiation 28 (6), 1985-1995, 2021
SuRVoS 2: Accelerating annotation and segmentation for large volumetric bioimage workflows across modalities and scales
A Pennington, ONF King, WM Tun, EML Ho, I Luengo, MC Darrow, ...
Frontiers in Cell and Developmental Biology 10, 842342, 2022
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