Antibody targeting intracellular oncogenic Ras mutants exerts anti-tumour effects after systemic administration SM Shin, DK Choi, K Jung, J Bae, J Kim, S Park, KH Song, YS Kim Nature communications 8 (1), 15090, 2017 | 138 | 2017 |
Cellular internalization mechanism and intracellular trafficking of filamentous M13 phages displaying a cell-penetrating transbody and TAT peptide A Kim, TH Shin, SM Shin, CD Pham, DK Choi, MH Kwon, YS Kim PloS one 7 (12), e51813, 2012 | 67 | 2012 |
A general strategy for generating intact, full-length IgG antibodies that penetrate into the cytosol of living cells DK Choi, J Bae, SM Shin, JY Shin, S Kim, YS Kim MAbs 6 (6), 1402-1414, 2014 | 66 | 2014 |
Endosomal acidic pH-induced conformational changes of a cytosol-penetrating antibody mediate endosomal escape JS Kim, DK Choi, JY Shin, SM Shin, SW Park, HS Cho, YS Kim Journal of Controlled Release 235, 165-175, 2016 | 53 | 2016 |
Direct targeting of oncogenic RAS mutants with a tumor-specific cytosol-penetrating antibody inhibits RAS mutant–driven tumor growth SM Shin, JS Kim, SW Park, SY Jun, HJ Kweon, DK Choi, D Lee, YB Cho, ... Science Advances 6 (3), eaay2174, 2020 | 52 | 2020 |
Quantitative assessment of cellular uptake and cytosolic access of antibody in living cells by an enhanced split GFP complementation assay J Kim, DK Choi, S Park, SM Shin, J Bae, DM Kim, TH Yoo, YS Kim Biochemical and Biophysical Research Communications 467 (4), 771-777, 2015 | 45 | 2015 |
KRAS targeting antibody synergizes anti-cancer activity of gemcitabine against pancreatic cancer YW Kang, JE Lee, KH Jung, MK Son, SM Shin, SJ Kim, Z Fang, HH Yan, ... Cancer letters 438, 174-186, 2018 | 43 | 2018 |
Engineering of a tumor cell–specific, cytosol-penetrating antibody with high endosomal escape efficacy J Kim, JY Park, SM Shin, SW Park, SY Jun, JS Hong, DK Choi, YS Kim Biochemical and biophysical research communications 503 (4), 2510-2516, 2018 | 17 | 2018 |
Intracellular KRAS-specific antibody enhances the anti-tumor efficacy of gemcitabine in pancreatic cancer by inducing endosomal escape JE Lee, YW Kang, KH Jung, MK Son, SM Shin, JS Kim, SJ Kim, Z Fang, ... Cancer Letters 507, 97-111, 2021 | 9 | 2021 |
Infant antibody repertoires during the first two years of influenza vaccination M Kuraoka, NC Curtis, A Watanabe, H Tanno, S Shin, K Ye, E Macdonald, ... Mbio 13 (6), e02546-22, 2022 | 3 | 2022 |
Combination therapy of the active KRAS-targeting antibody inRas37 and a PI3K inhibitor in pancreatic cancer JE Lee, MG Woo, KH Jung, YW Kang, SM Shin, MK Son, Z Fang, HH Yan, ... Biomolecules & Therapeutics 30 (3), 274, 2022 | 3 | 2022 |
Method for inhibiting intracellular activated RAS using intact immunoglobulin-type antibody having cytosol-penetrating ability and use thereof YS Kim, DK Choi, S Shin, SH Kim US Patent 10,851,177, 2020 | 3 | 2020 |
Method for positioning, in cytoplasm, antibody having complete immunoglobulin form by penetrating antibody through cell membrane, and use for same YS Kim, DK Choi, S Shin, SH Kim US Patent 10,844,136, 2020 | 3 | 2020 |
Characteristics and functions of infection-enhancing antibodies to the N-terminal domain of SARS-CoV-2 RI Connor, MI Sakharkar, CG Rappazzo, CI Kaku, NC Curtis, S Shin, ... bioRxiv, 2023.09. 19.558444, 2023 | 1 | 2023 |
Characterization of SARS-CoV-2 Convalescent Patients' Serological Repertoire Reveals High Prevalence of Iso-RBD Antibodies NC Curtis, S Shin, AP Hederman, RI Connor, WF Wieland-Alter, S Ionov, ... bioRxiv, 2023.09. 08.556349, 2023 | 1 | 2023 |
Antibody inhibiting activated ras in cell by internalizing into cytosol of cell, and use thereof YS Kim, DK Choi, SM Shin, P Seong-Wook US Patent App. 16/764,517, 2020 | | 2020 |
A method for positioning, in the cytoplasm, an antibody with a complete immunoglobulic form using an antibody that penetrates the cell membrane, and its use YS Kim, DK Choi, SM Shin, SH Kim | | 2020 |
Abstract B28: Direct targeting oncogenic Ras mutants by IgG-format cytosol-penetrating antibody SM Shin, JS Kim, JS Hong, S Park, SY Jun, HJ Kweon, DK Choi, YS Kim Molecular Cancer Research 18 (5_Supplement), B28-B28, 2020 | | 2020 |
Direct targeting oncogenic Ras mutants by IgG-format cytosol-penetrating antibody. SM Shin, JS Kim, JS Hong, S Park, SY Jun, HJ Kweon, DK Choi, YS Kim MOLECULAR CANCER RESEARCH 18 (5), 66-67, 2020 | | 2020 |
Method for suppressing ras activated in cell by using antibody having cytoplasm penetration capacity and complete immunoglobulin form, and use for same YS Kim, DK Choi, SM Shin, SH Kim | | 2020 |