| Discriminative accuracy of plasma phospho-tau217 for Alzheimer disease vs other neurodegenerative disorders S Palmqvist, S Janelidze, YT Quiroz, H Zetterberg, F Lopera, E Stomrud, ... Jama 324 (8), 772-781, 2020 | 941 | 2020 |
| Pre-dementia clinical stages in presenilin 1 E280A familial early-onset Alzheimer's disease: a retrospective cohort study N Acosta-Baena, D Sepulveda-Falla, CM Lopera-Gómez, ... The Lancet Neurology 10 (3), 213-220, 2011 | 288 | 2011 |
| Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer’s disease J Rasmussen, J Mahler, N Beschorner, SA Kaeser, LM Häsler, ... Proceedings of the National Academy of Sciences 114 (49), 13018-13023, 2017 | 219 | 2017 |
| The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2 S Krasemann, U Haferkamp, S Pfefferle, MS Woo, F Heinrich, ... Stem cell reports 17 (2), 307-320, 2022 | 198 | 2022 |
| Qualitative changes in human γ-secretase underlie familial Alzheimer’s disease M Szaruga, S Veugelen, M Benurwar, S Lismont, D Sepulveda-Falla, ... Journal of Experimental Medicine 212 (12), 2003-2013, 2015 | 174 | 2015 |
| Familial Alzheimer’s disease–associated presenilin-1 alters cerebellar activity and calcium homeostasis D Sepulveda-Falla, A Barrera-Ocampo, C Hagel, A Korwitz, ... The Journal of clinical investigation 124 (4), 1552-1567, 2014 | 152 | 2014 |
| Plasma neurofilament light chain in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional and longitudinal cohort study YT Quiroz, H Zetterberg, EM Reiman, Y Chen, Y Su, JT Fox-Fuller, ... The Lancet Neurology 19 (6), 513-521, 2020 | 137 | 2020 |
| High molecular mass assemblies of amyloid-β oligomers bind prion protein in patients with Alzheimer’s disease F Dohler, D Sepulveda-Falla, S Krasemann, H Altmeppen, H Schlüter, ... Brain 137 (3), 873-886, 2014 | 136 | 2014 |
| APOE* E2 allele delays age of onset in PSEN1 E280A Alzheimer’s disease JI Vélez, F Lopera, D Sepulveda-Falla, HR Patel, AS Johar, A Chuah, ... Molecular psychiatry 21 (7), 916-924, 2016 | 129 | 2016 |
| Distinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer disease M Pera, D Alcolea, R Sánchez-Valle, C Guardia-Laguarta, ... Acta Neuropathologica 125, 201-213, 2013 | 129 | 2013 |
| Complement 3+-astrocytes are highly abundant in prion diseases, but their abolishment led to an accelerated disease course and early dysregulation of microglia K Hartmann, D Sepulveda-Falla, IVL Rose, C Madore, C Muth, ... Acta neuropathologica communications 7, 1-15, 2019 | 116 | 2019 |
| C455R notch3 mutation in a Colombian CADASIL kindred with early onset of stroke JF Arboleda–Velasquez, F Lopera, E Lopez, MP Frosch, ... Neurology 59 (2), 277-279, 2002 | 99 | 2002 |
| Deposition of hyperphosphorylated tau in cerebellum of PS1 E280A Alzheimer's disease D Sepulveda‐Falla, J Matschke, C Bernreuther, C Hagel, B Puig, ... Brain pathology 21 (4), 452-463, 2011 | 85 | 2011 |
| Resilience to autosomal dominant Alzheimer’s disease in a Reelin-COLBOS heterozygous man F Lopera, C Marino, AS Chandrahas, M O’Hare, ND Villalba-Moreno, ... Nature medicine 29 (5), 1243-1252, 2023 | 84 | 2023 |
| Phenotypic profile of early-onset familial Alzheimer's disease caused by presenilin-1 E280A mutation D Sepulveda-Falla, M Glatzel, F Lopera Journal of Alzheimer's Disease 32 (1), 1-12, 2012 | 81 | 2012 |
| Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer’s dementia D Sepulveda-Falla, JS Sanchez, MC Almeida, D Boassa, J Acosta-Uribe, ... Acta neuropathologica 144 (3), 589-601, 2022 | 55 | 2022 |
| Phagocytosis of apoptotic cells is specifically upregulated in ApoE4 expressing microglia in vitro C Muth, A Hartmann, D Sepulveda-Falla, M Glatzel, S Krasemann Frontiers in cellular neuroscience 13, 181, 2019 | 45 | 2019 |
| A multifactorial model of pathology for age of onset heterogeneity in familial Alzheimer’s disease D Sepulveda-Falla, L Chavez-Gutierrez, E Portelius, JI Vélez, S Dujardin, ... Acta neuropathologica 141, 217-233, 2021 | 43 | 2021 |
| Cerebral small vessel disease in sporadic and familial Alzheimer disease RN Kalaria, D Sepulveda-Falla The American journal of pathology 191 (11), 1888-1905, 2021 | 37 | 2021 |
| Immune activation in amyloid-β-related angiitis correlates with decreased parenchymal amyloid-β plaque load S Bogner, C Bernreuther, J Matschke, A Barrera-Ocampo, ... Neurodegenerative Diseases 13 (1), 38-44, 2013 | 36 | 2013 |
Francisco LoperaFull Professor of University of AntioquiaVerified email at gna.org.co
