Eric Leclerc
Eric Leclerc
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Cell culture in 3-dimensional microfluidic structure of PDMS (polydimethylsiloxane)
E Leclerc, Y Sakai, T Fujii
Biomedical microdevices 5, 109-114, 2003
Microfluidic PDMS (polydimethylsiloxane) bioreactor for large‐scale culture of hepatocytes
E Leclerc, Y Sakai, T Fujii
Biotechnology progress 20 (3), 750-755, 2004
Study of osteoblastic cells in a microfluidic environment
E Leclerc, B David, L Griscom, B Lepioufle, T Fujii, P Layrolle, ...
Biomaterials 27 (4), 586-595, 2006
Development of a renal microchip for in vitro distal tubule models
R Baudoin, L Griscom, M Monge, C Legallais, E Leclerc
Biotechnology progress 23 (5), 1245-1253, 2007
Trends in the development of microfluidic cell biochips for in vitro hepatotoxicity
R Baudoin, A Corlu, L Griscom, C Legallais, E Leclerc
Toxicology in Vitro 21 (4), 535-544, 2007
Behavior of HepG2/C3A cell cultures in a microfluidic bioreactor
R Baudoin, L Griscom, JM Prot, C Legallais, E Leclerc
Biochemical Engineering Journal 53 (2), 172-181, 2011
Flow of artificial microcapsules in microfluidic channels: A method for determining the elastic properties of the membrane
Y Lefebvre, E Leclerc, D Barthès-Biesel, J Walter, F Edwards-Lévy
Physics of Fluids 20 (12), 2008
Investigation of ifosfamide nephrotoxicity induced in a liver–kidney co‐culture biochip
L Choucha‐Snouber, C Aninat, L Grsicom, G Madalinski, C Brochot, ...
Biotechnology and bioengineering 110 (2), 597-608, 2013
Metabolomics-on-a-chip and predictive systems toxicology in microfluidic bioartificial organs
L Shintu, R Baudoin, V Navratil, JM Prot, C Pontoizeau, M Defernez, ...
Analytical chemistry 84 (4), 1840-1848, 2012
Silk and PEG as means to stiffen a parylene probe for insertion in the brain: toward a double time-scale tool for local drug delivery
A Lecomte, V Castagnola, E Descamps, L Dahan, MC Blatché, TM Dinis, ...
Journal of Micromechanics and Microengineering 25 (12), 125003, 2015
Metabolomics-on-a-chip of hepatotoxicity induced by anticancer drug flutamide and its active metabolite hydroxyflutamide using HepG2/C3a microfluidic biochips
L Choucha Snouber, A Bunescu, M Naudot, C Legallais, C Brochot, ...
Toxicological Sciences 132 (1), 8-20, 2013
Improvement of HepG2/C3a cell functions in a microfluidic biochip
JM Prot, C Aninat, L Griscom, F Razan, C Brochot, CG Guillouzo, ...
Biotechnology and bioengineering 108 (7), 1704-1715, 2011
Perfusion culture of fetal human hepatocytes in microfluidic environments
E Leclerc, Y Sakai, T Fujii
Biochemical engineering journal 20 (2-3), 143-148, 2004
Development of a new microfluidic platform integrating co-cultures of intestinal and liver cell lines
T Bricks, P Paullier, A Legendre, MJ Fleury, P Zeller, F Merlier, PM Anton, ...
Toxicology in Vitro 28 (5), 885-895, 2014
First pass intestinal and liver metabolism of paracetamol in a microfluidic platform coupled with a mathematical modeling as a means of evaluating ADME processes in humans
JM Prot, L Maciel, T Bricks, F Merlier, J Cotton, P Paullier, FY Bois, ...
Biotechnology and bioengineering 111 (10), 2027-2040, 2014
Predictive toxicology using systemic biology and liver microfluidic “on chip” approaches: application to acetaminophen injury
JM Prot, A Bunescu, B Elena-Herrmann, C Aninat, LC Snouber, L Griscom, ...
Toxicology and applied pharmacology 259 (3), 270-280, 2012
A cocktail of metabolic probes demonstrates the relevance of primary human hepatocyte cultures in a microfluidic biochip for pharmaceutical drug screening
JM Prot, O Videau, C Brochot, C Legallais, H Benech, E Leclerc
International journal of pharmaceutics 408 (1-2), 67-75, 2011
Characterizing the membrane properties of capsules flowing in a square-section microfluidic channel: Effects of the membrane constitutive law
XQ Hu, B Sévénié, AV Salsac, E Leclerc, D Barthès-Biesel
Physical Review E 87 (6), 063008, 2013
Comparison between measurements of elasticity and free amino group content of ovalbumin microcapsule membranes: discrimination of the cross-linking degree
TX Chu, AV Salsac, E Leclerc, D Barthès-Biesel, H Wurtz, ...
Journal of colloid and interface science 355 (1), 81-88, 2011
Metabolic characterization of primary rat hepatocytes cultivated in parallel microfluidic biochips
A Legendre, R Baudoin, G Alberto, P Paullier, M Naudot, T Bricks, ...
Journal of pharmaceutical sciences 102 (9), 3264-3276, 2013
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