In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates K Musunuru, AC Chadwick, T Mizoguchi, SP Garcia, JE DeNizio, ... Nature 593 (7859), 429-434, 2021 | 618 | 2021 |
A high-throughput platform to identify small-molecule inhibitors of CRISPR-Cas9 B Maji, SA Gangopadhyay, M Lee, M Shi, P Wu, R Heler, B Mok, D Lim, ... Cell 177 (4), 1067-1079. e19, 2019 | 191 | 2019 |
Precision control of CRISPR-Cas9 using small molecules and light SA Gangopadhyay, KJ Cox, D Manna, D Lim, B Maji, Q Zhou, ... Biochemistry 58 (4), 234-244, 2019 | 121 | 2019 |
A singular system with precise dosing and spatiotemporal control of CRISPR‐Cas9 D Manna, B Maji, SA Gangopadhyay, KJ Cox, Q Zhou, BK Law, ... Angewandte Chemie 131 (19), 6351-6355, 2019 | 48 | 2019 |
Simultaneous site-specific dual protein labeling using protein prenyltransferases Y Zhang, MJ Blanden, C Sudheer, SA Gangopadhyay, M Rashidian, ... Bioconjugate chemistry 26 (12), 2542-2553, 2015 | 46 | 2015 |
Expansion of protein farnesyltransferase specificity using “tunable” active site interactions: development of bioengineered prenylation pathways JL Hougland, SA Gangopadhyay, CA Fierke Journal of Biological Chemistry 287 (45), 38090-38100, 2012 | 29 | 2012 |
Targeted reengineering of protein geranylgeranyltransferase type I selectivity functionally implicates active-site residues in protein-substrate recognition SA Gangopadhyay, EL Losito, JL Hougland Biochemistry 53 (2), 434-446, 2014 | 22 | 2014 |
A general approach to identify cell-permeable and synthetic anti-CRISPR small molecules D Lim, Q Zhou, KJ Cox, BK Law, M Lee, P Kokkonda, V Sreekanth, ... Nature cell biology 24 (12), 1766-1775, 2022 | 9 | 2022 |
Simultaneous Analysis of a Non-Lipidated Protein and Its Lipidated Counterpart: Enabling Quantitative Investigation of Protein Lipidation’s Impact on Cellular Regulation A Shala-Lawrence, MJ Blanden, SM Krylova, SA Gangopadhyay, ... Analytical chemistry 89 (24), 13502-13507, 2017 | 8 | 2017 |
Inhibitors of rna-guided nuclease target binding and uses thereof A Choudhary, M Basudeb, SA GANGOPADHYAY, LEE Miseon, ... | 2 | 2020 |
Methods and compositions for optochemical control of crispr-cas9 A Choudhary, D Manna, B Maji, SA Gangopadhyay US Patent App. 17/270,196, 2021 | | 2021 |
Novel nucleic acid modifiers A Choudhary, D Lim, K Cox, SA Gangopadhyay US Patent App. 16/758,840, 2021 | | 2021 |
PYRROLO-[3,2-C]QUINOLINE DERIVATIVES AS INHIBITORS OF RNA-GUIDED NUCLEASE TARGET BINDING AND USES THEREOF Choudhary Amit, Maji Basudeb, Gangopadhyay Soumyashree Ashok, Lee Miseon ... US Patent WO/2020/068,304, 2020 | | 2020 |
METHODS AND COMPOSITIONS FOR OPTOCHEMICAL CONTROL OF CRISPR-CAS9 SAG Amit Choudhary, Debasish Manna, Basudeb Maji US Patent WO2,020,041,380, 2020 | | 2020 |
NOVEL NUCLEIC ACID MODIFIERS GSA Choudhary Amit, Lim Donghyun, Cox Kurt US Patent WO/2019/135,816, 2019 | | 2019 |
Small-Molecule Inhibitors of CRISPR-Cas9 D Trauner, M Reynders Synfacts 15 (08), 0936, 2019 | | 2019 |
Novel nucleic acid modifiers A Choudhary, D Lim, COX Kurt, SA GANGOPADHYAY | | 2019 |
A singular system with precise dosing and spatiotemporal control of CRISPR‐Cas9 AC Debasish Manna, Basudeb Maji, Soumyashree Ashok Gangopadhyay, Kurt J. Cox ... Angewandte Chemie International Edition, https://doi.org/10.1002/anie.201900788, 2019 | | 2019 |
Protein geranylgeranylation by GGTase-I: Reengineering GGTase-I substrate selectivity and development of a calibrated sensor for cellular GGTase-I activity S Gangopadhyay, E Losito, J Hougland ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016 | | 2016 |
PROTEIN PRENYLATION BY GERANYLGERANYLTRANSFERASE TYPE I (GGTASE-I): UNDERSTANDING THE SUBSTRATE RECOGNITION AND ACTIVITY REGULATION OF A MULTISPECIFIC ENZYME SA Gangopadhyay Syracuse University, 2016 | | 2016 |