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Jatin Narula
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Chromosomal arrangement of phosphorelay genes couples sporulation and DNA replication
J Narula, A Kuchina, DL Dong-yeon, M Fujita, GM SŁel, OA Igoshin
Cell 162 (2), 328-337, 2015
1032015
Ultrasensitivity of the Bacillus subtilis sporulation decision
J Narula, SN Devi, M Fujita, OA Igoshin
Proceedings of the National Academy of Sciences 109 (50), E3513-E3522, 2012
862012
Bistable responses in bacterial genetic networks: designs and dynamical consequences
A Tiwari, JCJ Ray, J Narula, OA Igoshin
Mathematical biosciences 231 (1), 76-89, 2011
822011
Modeling reveals bistability and low-pass filtering in the network module determining blood stem cell fate
J Narula, AM Smith, B Gottgens, OA Igoshin
PLoS computational biology 6 (5), e1000771, 2010
772010
Impaired angiogenesis in aging myocardial microvascular endothelial cells is associated with reduced importin alpha and decreased nuclear transport of HIF1 alpha: mechanistic†…
A Ahluwalia, J Narula, MK Jones, X Deng, AS Tarnawski
Journal of physiology and pharmacology: an official journal of the Polish†…, 2010
572010
Triggering sporulation in Bacillus subtilis with artificial two‐component systems reveals the importance of proper Spo0A activation dynamics
M Vishnoi, J Narula, SN Devi, HA Dao, OA Igoshin, M Fujita
Molecular microbiology 90 (1), 181-194, 2013
562013
Slowdown of growth controls cellular differentiation
J Narula, A Kuchina, F Zhang, M Fujita, GM SŁel, OA Igoshin
Molecular systems biology 12 (5), 871, 2016
412016
A novel GUCY2C-CD3 T-cell engaging bispecific construct (PF-07062119) for the treatment of gastrointestinal cancers
D Mathur, AR Root, B Bugaj-Gaweda, S Bisulco, X Tan, W Fang, ...
Clinical Cancer Research 26 (9), 2188-2202, 2020
402020
Maximum entropy production allows a simple representation of heterogeneity in semiarid ecosystems
SJ Schymanski, A Kleidon, M Stieglitz, J Narula
Philosophical Transactions of the Royal Society B: Biological Sciences 365†…, 2010
402010
One size does not fit all: navigating the multi-dimensional space to optimize T-cell engaging protein therapeutics
W Chen, F Yang, C Wang, J Narula, E Pascua, I Ni, S Ding, X Deng, ...
MAbs 13 (1), 1871171, 2021
342021
PF-07059013: a noncovalent modulator of hemoglobin for treatment of sickle cell disease
A Gopalsamy, AE Aulabaugh, A Barakat, KC Beaumont, S Cabral, ...
Journal of Medicinal Chemistry 64 (1), 326-342, 2020
342020
Functional requirements of cellular differentiation: lessons from Bacillus subtilis
J Narula, M Fujita, OA Igoshin
Current opinion in microbiology 34, 38-46, 2016
332016
Mathematical model of a gene regulatory network reconciles effects of genetic perturbations on hematopoietic stem cell emergence
J Narula, CJ Williams, A Tiwari, J Marks-Bluth, JE Pimanda, OA Igoshin
Developmental biology 379 (2), 258-269, 2013
252013
A quantitative systems pharmacology consortium approach to managing immunogenicity of therapeutic proteins
AM Kierzek, TP Hickling, I Figueroa, JC Kalvass, M Nijsen, K Mohan, ...
CPT: Pharmacometrics & Systems Pharmacology 8 (11), 773, 2019
232019
Haider N, Virmani R, DiSalvo TG, Kolodgie FD, Hajjar RJ, Schmidt U, Semigran MJ, Dec GW, Khaw BA
J Narula
Apoptosis in myocytes in end-stage heart failure. N Engl J Med 335, 1182-1189, 1996
211996
Importance of feedback and feedforward loops to adaptive immune response modeling
A Rahman, A Tiwari, J Narula, T Hickling
CPT: Pharmacometrics & Systems Pharmacology 7 (10), 621-628, 2018
202018
Thermodynamic models of combinatorial gene regulation by distant enhancers
J Narula, OA Igoshin
IET Systems Biology 4 (6), 393-408, 2010
182010
Role of autoregulation and relative synthesis of operon partners in alternative sigma factor networks
J Narula, A Tiwari, OA Igoshin
PLoS Computational Biology 12 (12), e1005267, 2016
152016
Pandey P, Arbustini E, Haider N, Narula N, Kolodgie FD, Dal Bello B, Semigran MJ, Bielsa-Masdeu A, Dec GW, Israels S, Ballester M, Virmani R, Saxena S, and Kharbanda S
J Narula
Apoptosis in heart failure: release of cytochrome c from mitochondria and†…, 1999
131999
Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific antibody for the treatment of solid tumors
AR Root, G Guntas, M Katragadda, JR Apgar, J Narula, CS Chang, ...
MAbs 13 (1), 1850395, 2021
122021
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Articles 1–20