| Chromosomal arrangement of phosphorelay genes couples sporulation and DNA replication J Narula, A Kuchina, DL Dong-yeon, M Fujita, GM Süel, OA Igoshin Cell 162 (2), 328-337, 2015 | 104 | 2015 |
| Ultrasensitivity of the Bacillus subtilis sporulation decision J Narula, SN Devi, M Fujita, OA Igoshin Proceedings of the National Academy of Sciences 109 (50), E3513-E3522, 2012 | 90 | 2012 |
| Bistable responses in bacterial genetic networks: designs and dynamical consequences A Tiwari, JCJ Ray, J Narula, OA Igoshin Mathematical biosciences 231 (1), 76-89, 2011 | 83 | 2011 |
| Modeling reveals bistability and low-pass filtering in the network module determining blood stem cell fate J Narula, AM Smith, B Gottgens, OA Igoshin PLoS computational biology 6 (5), e1000771, 2010 | 78 | 2010 |
| Impaired angiogenesis in aging myocardial microvascular endothelial cells is associated with reduced importin alpha and decreased nuclear transport of HIF1 alpha: mechanistic … A Ahluwalia, J Narula, MK Jones, X Deng, AS Tarnawski Journal of physiology and pharmacology: an official journal of the Polish …, 2010 | 59 | 2010 |
| Triggering sporulation in Bacillus subtilis with artificial two‐component systems reveals the importance of proper Spo0A activation dynamics M Vishnoi, J Narula, SN Devi, HA Dao, OA Igoshin, M Fujita Molecular microbiology 90 (1), 181-194, 2013 | 57 | 2013 |
| A novel GUCY2C-CD3 T-cell engaging bispecific construct (PF-07062119) for the treatment of gastrointestinal cancers D Mathur, AR Root, B Bugaj-Gaweda, S Bisulco, X Tan, W Fang, ... Clinical Cancer Research 26 (9), 2188-2202, 2020 | 46 | 2020 |
| Slowdown of growth controls cellular differentiation J Narula, A Kuchina, F Zhang, M Fujita, GM Süel, OA Igoshin Molecular systems biology 12 (5), 871, 2016 | 45 | 2016 |
| Maximum entropy production allows a simple representation of heterogeneity in semiarid ecosystems SJ Schymanski, A Kleidon, M Stieglitz, J Narula Philosophical Transactions of the Royal Society B: Biological Sciences 365 …, 2010 | 41 | 2010 |
| One size does not fit all: navigating the multi-dimensional space to optimize T-cell engaging protein therapeutics W Chen, F Yang, C Wang, J Narula, E Pascua, I Ni, S Ding, X Deng, ... MAbs 13 (1), 1871171, 2021 | 40 | 2021 |
| PF-07059013: a noncovalent modulator of hemoglobin for treatment of sickle cell disease A Gopalsamy, AE Aulabaugh, A Barakat, KC Beaumont, S Cabral, ... Journal of Medicinal Chemistry 64 (1), 326-342, 2020 | 36 | 2020 |
| Functional requirements of cellular differentiation: lessons from Bacillus subtilis J Narula, M Fujita, OA Igoshin Current opinion in microbiology 34, 38-46, 2016 | 35 | 2016 |
| A quantitative systems pharmacology consortium approach to managing immunogenicity of therapeutic proteins AM Kierzek, TP Hickling, I Figueroa, JC Kalvass, M Nijsen, K Mohan, ... CPT: Pharmacometrics & Systems Pharmacology 8 (11), 773, 2019 | 25 | 2019 |
| Mathematical model of a gene regulatory network reconciles effects of genetic perturbations on hematopoietic stem cell emergence J Narula, CJ Williams, A Tiwari, J Marks-Bluth, JE Pimanda, OA Igoshin Developmental biology 379 (2), 258-269, 2013 | 25 | 2013 |
| Importance of feedback and feedforward loops to adaptive immune response modeling A Rahman, A Tiwari, J Narula, T Hickling CPT: Pharmacometrics & Systems Pharmacology 7 (10), 621-628, 2018 | 24 | 2018 |
| Role of autoregulation and relative synthesis of operon partners in alternative sigma factor networks J Narula, A Tiwari, OA Igoshin PLoS Computational Biology 12 (12), e1005267, 2016 | 19 | 2016 |
| Thermodynamic models of combinatorial gene regulation by distant enhancers J Narula, OA Igoshin IET Systems Biology 4 (6), 393-408, 2010 | 19 | 2010 |
| Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific antibody for the treatment of solid tumors AR Root, G Guntas, M Katragadda, JR Apgar, J Narula, CS Chang, ... MAbs 13 (1), 1850395, 2021 | 13 | 2021 |
| Quantitative systems pharmacology modeling provides insight into inter‐mouse variability of anti‐CTLA4 response W Qiao, L Lin, C Young, J Narula, F Hua, A Matteson, A Hooper, ... CPT: Pharmacometrics & Systems Pharmacology 11 (7), 880-893, 2022 | 7 | 2022 |
| Preclinical Evaluation of 89Zr-Df-IAB22M2C PET as an Imaging Biomarker for the Development of the GUCY2C-CD3 Bispecific PF-07062119 as a T Cell Engaging … KP Maresca, J Chen, D Mathur, A Giddabasappa, A Root, J Narula, ... Molecular Imaging and Biology 23 (6), 941-951, 2021 | 7 | 2021 |
Oleg A. IgoshinProfessor of Bioengineering, Rice UniversityVerified email at rice.edu
