Walter Chazin
Walter Chazin
Chancellor's Chair in Medicine, Departments of Biochemistry and Chemistry, Vanderbilt University
Verified email at - Homepage
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Metal chelation and inhibition of bacterial growth in tissue abscesses
BD Corbin, EH Seeley, A Raab, J Feldmann, MR Miller, VJ Torres, ...
Science 319 (5865), 962-965, 2008
Nutrient metal sequestration by calprotectin inhibits bacterial superoxide defense, enhancing neutrophil killing of Staphylococcus aureus
TE Kehl-Fie, S Chitayat, MI Hood, S Damo, N Restrepo, C Garcia, ...
Cell host & microbe 10 (2), 158-164, 2011
Molecular basis for manganese sequestration by calprotectin and roles in the innate immune response to invading bacterial pathogens
SM Damo, TE Kehl-Fie, N Sugitani, ME Holt, S Rathi, WJ Murphy, ...
Proceedings of the National Academy of Sciences 110 (10), 3841-3846, 2013
Calmodulin mutations associated with recurrent cardiac arrest in infants
L Crotti, CN Johnson, E Graf, GM De Ferrari, BF Cuneo, M Ovadia, ...
Circulation 127 (9), 1009-1017, 2013
Rotational diffusion anisotropy of proteins from simultaneous analysis of 15N and 13Cα nuclear spin relaxation
LK Lee, M Rance, WJ Chazin, AG Palmer
Journal of biomolecular NMR 9, 287-298, 1997
S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP kinase-dependent pathway
S Ghavami, I Rashedi, BM Dattilo, M Eshraghi, WJ Chazin, M Hashemi, ...
Journal of Leucocyte Biology 83 (6), 1484-1492, 2008
The S100A8/A9 heterodimer amplifies proinflammatory cytokine production by macrophages via activation of nuclear factor kappa B and p38 mitogen-activated protein kinase in …
K Sunahori, M Yamamura, J Yamana, K Takasugi, M Kawashima, ...
Arthritis research & therapy 8, 1-12, 2006
Structural insights into the U-box, a domain associated with multi-ubiquitination
MD Ohi, CW Vander Kooi, JA Rosenberg, WJ Chazin, KL Gould
Nature Structural & Molecular Biology 10 (4), 250-255, 2003
Zinc sequestration by the neutrophil protein calprotectin enhances Salmonella growth in the inflamed gut
JZ Liu, S Jellbauer, AJ Poe, V Ton, M Pesciaroli, TE Kehl-Fie, ...
Cell host & microbe 11 (3), 227-239, 2012
Structure of an E3: E2∼ Ub complex reveals an allosteric mechanism shared among RING/U-box ligases
JN Pruneda, PJ Littlefield, SE Soss, KA Nordquist, WJ Chazin, PS Brzovic, ...
Molecular cell 47 (6), 933-942, 2012
Target selectivity in EF-hand calcium binding proteins
S Bhattacharya, CG Bunick, WJ Chazin
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1742 (1-3), 69-79, 2004
Structural basis for the recognition of DNA repair proteins UNG2, XPA, and RAD52 by replication factor RPA
G Mer, A Bochkarev, R Gupta, E Bochkareva, L Frappier, CJ Ingles, ...
Cell 103 (3), 449-456, 2000
Suppression of the effects of cross-correlation between dipolar and anisotropic chemical shift relaxation mechanisms in the measurement of spin-spin relaxation rates
AG Palmer III, NJ Skelton, WJ Chazin, PE Wright, M Rance
Molecular Physics 75 (3), 699-711, 1992
Structures of EF-hand Ca 2+-binding proteins: diversity in the organization, packing and response to Ca 2+ binding
MR Nelson, WJ Chazin
Biometals 11, 297-318, 1998
Identification of an Acinetobacter baumannii Zinc Acquisition System that Facilitates Resistance to Calprotectin-mediated Zinc Sequestration
MI Hood, BL Mortensen, JL Moore, Y Zhang, TE Kehl-Fie, N Sugitani, ...
PLoS pathogens 8 (12), e1003068, 2012
Structural basis for ligand recognition and activation of RAGE
M Koch, S Chitayat, BM Dattilo, A Schiefner, J Diez, WJ Chazin, G Fritz
Structure 18 (10), 1342-1352, 2010
Zinc-reversible antimicrobial activity of recombinant calprotectin (migration inhibitory factor—related proteins 8 and 14)
PG Sohnle, MJ Hunter, B Hahn, WJ Chazin
The Journal of infectious diseases 182 (4), 1272-1275, 2000
High level expression and dimer characterization of the S100 EF-hand proteins, migration inhibitory factor-related proteins 8 and 14
MJ Hunter, WJ Chazin
Journal of Biological Chemistry 273 (20), 12427-12435, 1998
Dietary zinc alters the microbiota and decreases resistance to Clostridium difficile infection
JP Zackular, JL Moore, AT Jordan, LJ Juttukonda, MJ Noto, MR Nicholson, ...
Nature medicine 22 (11), 1330-1334, 2016
ETAA1 acts at stalled replication forks to maintain genome integrity
TE Bass, JW Luzwick, G Kavanaugh, C Carroll, H Dungrawala, GG Glick, ...
Nature cell biology 18 (11), 1185-1195, 2016
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