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Travis W. Bainbridge
Travis W. Bainbridge
Scientist 4 in Large Molecule Drug Discovery, Genentech
Verified email at gene.com - Homepage
Title
Cited by
Cited by
Year
Single-Cell RNA Sequencing Reveals Stromal Evolution into LRRC15+ Myofibroblasts as a Determinant of Patient Response to Cancer Immunotherapy
CX Dominguez, S Müller, S Keerthivasan, H Koeppen, J Hung, S Gierke, ...
Cancer discovery 10 (2), 232-253, 2020
5302020
USP7 small-molecule inhibitors interfere with ubiquitin binding
L Kategaya, P Di Lello, L Rougé, R Pastor, KR Clark, J Drummond, ...
Nature 550 (7677), 534-538, 2017
2832017
Effector-attenuating substitutions that maintain antibody stability and reduce toxicity in mice
M Lo, HS Kim, RK Tong, TW Bainbridge, JM Vernes, Y Zhang, YL Lin, ...
Journal of Biological Chemistry 292 (9), 3900-3908, 2017
2582017
Targeting PTPRK-RSPO3 colon tumours promotes differentiation and loss of stem-cell function
EE Storm, S Durinck, F de Sousa E Melo, J Tremayne, N Kljavin, C Tan, ...
Nature 529 (7584), 97-100, 2016
2322016
Molecular mechanisms of Alzheimer disease protection by the A673T allele of amyloid precursor protein
JA Maloney, T Bainbridge, A Gustafson, S Zhang, R Kyauk, P Steiner, ...
Journal of Biological Chemistry 289 (45), 30990-31000, 2014
2122014
Fibroblast activation protein cleaves and inactivates fibroblast growth factor 21
DR Dunshee, TW Bainbridge, NM Kljavin, J Zavala-Solorio, ...
Journal of Biological Chemistry 291 (11), 5986-5996, 2016
1432016
Structure of crenezumab complex with Aβ shows loss of β-hairpin
M Ultsch, B Li, T Maurer, M Mathieu, O Adolfsson, A Muhs, A Pfeifer, ...
Scientific reports 6 (1), 39374, 2016
1162016
Sustained brown fat stimulation and insulin sensitization by a humanized bispecific antibody agonist for fibroblast growth factor receptor 1/βKlotho complex
G Kolumam, MZ Chen, R Tong, J Zavala-Solorio, L Kates, N van Bruggen, ...
EBioMedicine 2 (7), 730-743, 2015
1092015
Molecular understanding of USP7 substrate recognition and C-terminal activation
L Rougé, TW Bainbridge, M Kwok, R Tong, P Di Lello, IE Wertz, T Maurer, ...
Structure 24 (8), 1335-1345, 2016
932016
Evolutionary Divergence in the Catalytic Activity of the CAM-1, ROR1 and ROR2 Kinase Domains
TW Bainbridge, VI DeAlmeida, A Izrael-Tomasevic, C Chalouni, B Pan, ...
PloS one 9 (7), e102695, 2014
462014
IL-1R1–dependent signaling coordinates epithelial regeneration in response to intestinal damage
CB Cox, EE Storm, VN Kapoor, J Chavarria-Smith, DL Lin, L Wang, Y Li, ...
Science Immunology 6 (59), eabe8856, 2021
372021
Selective homogeneous assay for circulating endopeptidase fibroblast activation protein (FAP)
TW Bainbridge, DR Dunshee, NM Kljavin, NJ Skelton, J Sonoda, JA Ernst
Scientific Reports 7 (1), 12524, 2017
322017
Vaccinia H5 is a multifunctional protein involved in viral DNA replication, postreplicative gene transcription, and virion morphogenesis
SM D'Costa, TW Bainbridge, SE Kato, C Prins, K Kelley, RC Condit
Virology 401 (1), 49-60, 2010
302010
Characterization of the selective in vitro and in vivo binding properties of crenezumab to oligomeric Aβ
WJ Meilandt, JA Maloney, J Imperio, G Lalehzadeh, T Earr, S Crowell, ...
Alzheimer's research & therapy 11, 1-14, 2019
262019
Marker rescue mapping of the combined Condit/Dales collection of temperature-sensitive vaccinia virus mutants
SEM Kato, N Moussatche, SM D'Costa, TW Bainbridge, C Prins, AL Strahl, ...
Virology 375 (1), 213-222, 2008
262008
Purification and properties of the vaccinia virus mRNA processing factor
SM D'Costa, TW Bainbridge, RC Condit
Journal of biological chemistry 283 (9), 5267-5275, 2008
172008
Adaptive adipose tissue stromal plasticity in response to cold stress and antibody-based metabolic therapy
JC Chang, S Durinck, MZ Chen, N Martinez-Martin, JA Zhang, I Lehoux, ...
Scientific Reports 9 (1), 8833, 2019
152019
Biochemical and biophysical properties of a putative hub protein expressed by vaccinia virus
NE Kay, TW Bainbridge, RC Condit, MR Bubb, RE Judd, ...
Journal of Biological Chemistry 288 (16), 11470-11481, 2013
112013
Characterization of the selective in vivo and in vitro binding properties of crenezumab: insights into crenezumab’s unique mechanism of action (P6. 174)
W Meilandt, J Maloney, J Imperio, T Bainbridge, M Reichelt, D Mandikian, ...
Neurology 90 (15 Supplement), 2018
52018
Crenezumab’s Preferential Binding Of Oligomeric Amyloid-Beta Species Underlies Its Unique Mechanism Of Action (S7. 005)
J Atwal, W Meilandt, M Wetzel-Smith, B Li, T Bainbridge, M Reichelt, ...
Neurology 88 (16 Supplement), 2017
32017
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