| PLINK: a tool set for whole-genome association and population-based linkage analyses S Purcell, B Neale, K Todd-Brown, L Thomas, MAR Ferreira, D Bender, ... The American journal of human genetics 81 (3), 559-575, 2007 | 34492 | 2007 |
| Analysis of protein-coding genetic variation in 60,706 humans M Lek, KJ Karczewski, EV Minikel, KE Samocha, E Banks, T Fennell, ... Nature 536 (7616), 285-291, 2016 | 10716 | 2016 |
| The mutational constraint spectrum quantified from variation in 141,456 humans KJ Karczewski, LC Francioli, G Tiao, BB Cummings, J Alföldi, Q Wang, ... Nature 581 (7809), 434-443, 2020 | 8374 | 2020 |
| Biological insights from 108 schizophrenia-associated genetic loci C Pantelis, GN Papadimitriou, S Papiol, E Parkhomenko, MT Pato, ... Nature 511 (7510), 421-427, 2014 | 7765 | 2014 |
| Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases M Verbanck, CY Chen, B Neale, R Do Nature genetics 50 (5), 693-698, 2018 | 6229 | 2018 |
| LD Score regression distinguishes confounding from polygenicity in genome-wide association studies BK Bulik-Sullivan, PR Loh, HK Finucane, S Ripke, J Yang, ... Nature genetics 47 (3), 291-295, 2015 | 4997 | 2015 |
| An atlas of genetic correlations across human diseases and traits B Bulik-Sullivan, HK Finucane, V Anttila, A Gusev, FR Day, PR Loh, ... Nature genetics 47 (11), 1236-1241, 2015 | 3908 | 2015 |
| Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence G Genovese, AK Kähler, RE Handsaker, J Lindberg, SA Rose, ... New England Journal of Medicine 371 (26), 2477-2487, 2014 | 3635 | 2014 |
| Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis Cross-Disorder Group of the Psychiatric Genomics Consortium The Lancet 381 (9875), 1371-1379, 2013 | 3125 | 2013 |
| Synaptic, transcriptional and chromatin genes disrupted in autism S De Rubeis, X He, AP Goldberg, CS Poultney, K Samocha, ... Nature 515 (7526), 209-215, 2014 | 2983 | 2014 |
| Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study P Lichtenstein, BH Yip, C Björk, Y Pawitan, TD Cannon, PF Sullivan, ... The Lancet 373 (9659), 234-239, 2009 | 2533 | 2009 |
| Partitioning heritability by functional annotation using genome-wide association summary statistics HK Finucane, B Bulik-Sullivan, A Gusev, G Trynka, Y Reshef, PR Loh, ... Nature genetics 47 (11), 1228-1235, 2015 | 2487 | 2015 |
| Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs B Devlin, JR Kelsoe, P Sklar, MJ Daly, MC O'Donovan, N Craddock, ... Nature genetics 45 (9), 984-994, 2013 | 2432 | 2013 |
| Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder D Demontis, RK Walters, J Martin, M Mattheisen, TD Als, E Agerbo, ... Nature genetics 51 (1), 63-75, 2019 | 2344 | 2019 |
| Clinical use of current polygenic risk scores may exacerbate health disparities AR Martin, M Kanai, Y Kamatani, Y Okada, BM Neale, MJ Daly Nature genetics 51 (4), 584-591, 2019 | 2312 | 2019 |
| Identification of common genetic risk variants for autism spectrum disorder J Grove, S Ripke, TD Als, M Mattheisen, RK Walters, H Won, J Pallesen, ... Nature genetics 51 (3), 431-444, 2019 | 2202 | 2019 |
| Patterns and rates of exonic de novo mutations in autism spectrum disorders BM Neale, Y Kou, L Liu, A Ma’Ayan, KE Samocha, A Sabo, CF Lin, ... Nature 485 (7397), 242-245, 2012 | 2099 | 2012 |
| Genome-wide association study identifies five new schizophrenia loci Nature genetics 43 (10), 969-976, 2011 | 2065 | 2011 |
| Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism FK Satterstrom, JA Kosmicki, J Wang, MS Breen, S De Rubeis, JY An, ... Cell 180 (3), 568-584. e23, 2020 | 2036 | 2020 |
| Genome-wide association analysis identifies 13 new risk loci for schizophrenia S Ripke, C O'dushlaine, K Chambert, JL Moran, AK Kähler, S Akterin, ... Nature genetics 45 (10), 1150-1159, 2013 | 1808 | 2013 |
Shaun PurcellSleep & Neurogenetics Lab, Brigham & Women's Hospital, BostonVerified email at bwh.harvard.edu
