| Cationic lipid-DNA complexes for gene therapy: understanding the relationship between complex structure and gene delivery pathways at the molecular level K Ewert, NL Slack, A Ahmad, HM Evans, AJ Lin, CE Samuel, CR Safinya Current medicinal chemistry 11 (2), 133-149, 2004 | 289 | 2004 |
| A columnar phase of dendritic lipid-based cationic liposome-DNA complexes for gene delivery: hexagonally ordered cylindrical micelles embedded in a DNA honeycomb lattice KK Ewert, HM Evans, A Zidovska, NF Bouxsein, A Ahmad, CR Safinya Journal of the American Chemical Society 128 (12), 3998-4006, 2006 | 284 | 2006 |
| Structure and gene silencing activities of monovalent and pentavalent cationic lipid vectors complexed with siRNA NF Bouxsein, CS McAllister, KK Ewert, CE Samuel, CR Safinya Biochemistry 46 (16), 4785-4792, 2007 | 258 | 2007 |
| New multivalent cationic lipids reveal bell curve for transfection efficiency versus membrane charge density: lipid–DNA complexes for gene delivery A Ahmad, HM Evans, K Ewert, CX George, CE Samuel, CR Safinya The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2005 | 232 | 2005 |
| Highly efficient gene silencing activity of siRNA embedded in a nanostructured gyroid cubic lipid matrix C Leal, NF Bouxsein, KK Ewert, CR Safinya Journal of the American Chemical Society 132 (47), 16841-16847, 2010 | 211 | 2010 |
| Cationic lipid-DNA complexes for non-viral gene therapy: relating supramolecular structures to cellular pathways K Ewert, A Ahmad, HM Evans, CR Safinya Expert opinion on biological therapy 5 (1), 33-53, 2005 | 192 | 2005 |
| Efficient synthesis and cell-transfection properties of a new multivalent cationic lipid for nonviral gene delivery K Ewert, A Ahmad, HM Evans, HW Schmidt, CR Safinya Journal of medicinal chemistry 45 (23), 5023-5029, 2002 | 180 | 2002 |
| Cationic liposome–nucleic acid complexes for gene delivery and silencing: pathways and mechanisms for plasmid DNA and siRNA KK Ewert, A Zidovska, A Ahmad, NF Bouxsein, HM Evans, CS McAllister, ... Nucleic Acid Transfection, 191-226, 2010 | 177 | 2010 |
| Endosomal escape and transfection efficiency of PEGylated cationic liposome–DNA complexes prepared with an acid-labile PEG-lipid CL Chan, RN Majzoub, RS Shirazi, KK Ewert, YJ Chen, KS Liang, ... Biomaterials 33 (19), 4928-4935, 2012 | 173 | 2012 |
| Synchrotron X-ray diffraction study of microtubules buckling and bundling under osmotic stress: a probe of interprotofilament interactions DJ Needleman, MA Ojeda-Lopez, U Raviv, K Ewert, JB Jones, HP Miller, ... Physical review letters 93 (19), 198104, 2004 | 138 | 2004 |
| Cationic liposome–nucleic acid complexes for gene delivery and gene silencing CR Safinya, KK Ewert, RN Majzoub, C Leal New Journal of Chemistry 38 (11), 5164-5172, 2014 | 112 | 2014 |
| Structural polymorphism of DNA-dendrimer complexes HM Evans, A Ahmad, K Ewert, T Pfohl, A Martin-Herranz, RF Bruinsma, ... Physical review letters 91 (7), 075501, 2003 | 102 | 2003 |
| Synthesis and characterization of degradable multivalent cationic lipids with disulfide-bond spacers for gene delivery RS Shirazi, KK Ewert, C Leal, RN Majzoub, NF Bouxsein, CR Safinya Biochimica et Biophysica Acta (BBA)-Biomembranes 1808 (9), 2156-2166, 2011 | 99 | 2011 |
| Radial compression of microtubules and the mechanism of action of taxol and associated proteins DJ Needleman, MA Ojeda-Lopez, U Raviv, K Ewert, HP Miller, L Wilson, ... Biophysical journal 89 (5), 3410-3423, 2005 | 98 | 2005 |
| Materials chemistry: liposomes derived from molecular vases CR Safinya, KK Ewert Nature 489 (7416), 372, 2012 | 97 | 2012 |
| Cationic liposome–nucleic acid nanoparticle assemblies with applications in gene delivery and gene silencing RN Majzoub, KK Ewert, CR Safinya Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2016 | 96 | 2016 |
| Uptake and transfection efficiency of PEGylated cationic liposome–DNA complexes with and without RGD-tagging RN Majzoub, CL Chan, KK Ewert, BFB Silva, KS Liang, EL Jacovetty, ... Biomaterials 35 (18), 4996-5005, 2014 | 95 | 2014 |
| Cationic Liposomes as Vectors for Nucleic Acid and Hydrophobic Drug Therapeutics KK Ewert, P Scodeller, L Simón-Gracia, VM Steffes, EA Wonder, ... Pharmaceutics 13 (9), 1365, 2021 | 92 | 2021 |
| Cationic liposome–DNA complexes: from liquid crystal science to gene delivery applications CR Safinya, K Ewert, A Ahmad, HM Evans, U Raviv, DJ Needleman, ... Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2006 | 91 | 2006 |
| Surface functionalized cationic lipid-DNA complexes for gene delivery: PEGylated lamellar complexes exhibit distinct DNA-DNA interaction regimes A Martin-Herranz, A Ahmad, HM Evans, K Ewert, U Schulze, CR Safinya Biophysical journal 86 (2), 1160-1168, 2004 | 87 | 2004 |
Cyrus R SafinyaDistinguished Professor of Materials, University of California at Santa BarbaraVerified email at ucsb.edu
