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Kai Ewert
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Cationic lipid-DNA complexes for gene therapy: understanding the relationship between complex structure and gene delivery pathways at the molecular level
K Ewert, NL Slack, A Ahmad, HM Evans, AJ Lin, CE Samuel, CR Safinya
Current medicinal chemistry 11 (2), 133-149, 2004
2842004
A columnar phase of dendritic lipid-based cationic liposome-DNA complexes for gene delivery: hexagonally ordered cylindrical micelles embedded in a DNA honeycomb lattice
KK Ewert, HM Evans, A Zidovska, NF Bouxsein, A Ahmad, CR Safinya
Journal of the American Chemical Society 128 (12), 3998-4006, 2006
2792006
Structure and gene silencing activities of monovalent and pentavalent cationic lipid vectors complexed with siRNA
NF Bouxsein, CS McAllister, KK Ewert, CE Samuel, CR Safinya
Biochemistry 46 (16), 4785-4792, 2007
2532007
New multivalent cationic lipids reveal bell curve for transfection efficiency versus membrane charge density: lipid–DNA complexes for gene delivery
A Ahmad, HM Evans, K Ewert, CX George, CE Samuel, CR Safinya
The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2005
2292005
Highly efficient gene silencing activity of siRNA embedded in a nanostructured gyroid cubic lipid matrix
C Leal, NF Bouxsein, KK Ewert, CR Safinya
Journal of the American Chemical Society 132 (47), 16841-16847, 2010
2012010
Cationic lipid-DNA complexes for non-viral gene therapy: relating supramolecular structures to cellular pathways
K Ewert, A Ahmad, HM Evans, CR Safinya
Expert opinion on biological therapy 5 (1), 33-53, 2005
1892005
Efficient synthesis and cell-transfection properties of a new multivalent cationic lipid for nonviral gene delivery
K Ewert, A Ahmad, HM Evans, HW Schmidt, CR Safinya
Journal of medicinal chemistry 45 (23), 5023-5029, 2002
1762002
Cationic liposome–nucleic acid complexes for gene delivery and silencing: pathways and mechanisms for plasmid DNA and siRNA
KK Ewert, A Zidovska, A Ahmad, NF Bouxsein, HM Evans, CS McAllister, ...
Nucleic Acid Transfection, 191-226, 2010
1702010
Endosomal escape and transfection efficiency of PEGylated cationic liposome–DNA complexes prepared with an acid-labile PEG-lipid
CL Chan, RN Majzoub, RS Shirazi, KK Ewert, YJ Chen, KS Liang, ...
Biomaterials 33 (19), 4928-4935, 2012
1662012
Synchrotron X-ray diffraction study of microtubules buckling and bundling under osmotic stress: a probe of interprotofilament interactions
DJ Needleman, MA Ojeda-Lopez, U Raviv, K Ewert, JB Jones, HP Miller, ...
Physical review letters 93 (19), 198104, 2004
1382004
Cationic liposome–nucleic acid complexes for gene delivery and gene silencing
CR Safinya, KK Ewert, RN Majzoub, C Leal
New Journal of Chemistry 38 (11), 5164-5172, 2014
1112014
Structural polymorphism of DNA-dendrimer complexes
HM Evans, A Ahmad, K Ewert, T Pfohl, A Martin-Herranz, RF Bruinsma, ...
Physical review letters 91 (7), 075501, 2003
1012003
Synthesis and characterization of degradable multivalent cationic lipids with disulfide-bond spacers for gene delivery
RS Shirazi, KK Ewert, C Leal, RN Majzoub, NF Bouxsein, CR Safinya
Biochimica et Biophysica Acta (BBA)-Biomembranes 1808 (9), 2156-2166, 2011
982011
Radial compression of microtubules and the mechanism of action of taxol and associated proteins
DJ Needleman, MA Ojeda-Lopez, U Raviv, K Ewert, HP Miller, L Wilson, ...
Biophysical journal 89 (5), 3410-3423, 2005
982005
Materials chemistry: liposomes derived from molecular vases
CR Safinya, KK Ewert
Nature 489 (7416), 372, 2012
952012
Uptake and transfection efficiency of PEGylated cationic liposome–DNA complexes with and without RGD-tagging
RN Majzoub, CL Chan, KK Ewert, BFB Silva, KS Liang, EL Jacovetty, ...
Biomaterials 35 (18), 4996-5005, 2014
932014
Cationic liposome–DNA complexes: from liquid crystal science to gene delivery applications
CR Safinya, K Ewert, A Ahmad, HM Evans, U Raviv, DJ Needleman, ...
Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2006
902006
Cationic liposome–nucleic acid nanoparticle assemblies with applications in gene delivery and gene silencing
RN Majzoub, KK Ewert, CR Safinya
Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2016
892016
Surface functionalized cationic lipid-DNA complexes for gene delivery: PEGylated lamellar complexes exhibit distinct DNA-DNA interaction regimes
A Martin-Herranz, A Ahmad, HM Evans, K Ewert, U Schulze, CR Safinya
Biophysical journal 86 (2), 1160-1168, 2004
882004
Cationic Liposomes as Vectors for Nucleic Acid and Hydrophobic Drug Therapeutics
KK Ewert, P Scodeller, L Simón-Gracia, VM Steffes, EA Wonder, ...
Pharmaceutics 13 (9), 1365, 2021
762021
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