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Eva Maria Mandelkow
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
14127*2021
Assembly of τ protein into Alzheimer paired helical filaments depends on a local sequence motif (306VQIVYK311) forming β structure
M Von Bergen, P Friedhoff, J Biernat, J Heberle, EM Mandelkow, ...
Proceedings of the National Academy of Sciences 97 (10), 5129-5134, 2000
12152000
Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease
JC Augustinack, A Schneider, EM Mandelkow, BT Hyman
Acta neuropathologica 103, 26-35, 2002
12002002
Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
K Stamer, R Vogel, E Thies, E Mandelkow, EM Mandelkow
The Journal of cell biology 156 (6), 1051-1063, 2002
11052002
MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption
G Drewes, A Ebneth, U Preuss, EM Mandelkow, E Mandelkow
Cell 89 (2), 297-308, 1997
10561997
Biochemistry and cell biology of tau protein in neurofibrillary degeneration
EM Mandelkow, E Mandelkow
Cold Spring Harbor perspectives in medicine 2 (7), a006247, 2012
10452012
Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease
A Ebneth, R Godemann, K Stamer, S Illenberger, B Trinczek, ...
The Journal of cell biology 143 (3), 777-794, 1998
10261998
Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding
J Biernat, N Gustke, G Drewes, E Mandelkow
Neuron 11 (1), 153-163, 1993
10131993
A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads
F Braak, H Braak, EM Mandelkow
Acta neuropathologica 87, 554-567, 1994
9961994
Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease: A PROPERTY COMMON TO MOST …
S Leclerc, M Garnier, R Hoessel, D Marko, JA Bibb, GL Snyder, ...
Journal of Biological Chemistry 276 (1), 251-260, 2001
9552001
Aβ oligomers cause localized Ca2+ elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines
H Zempel, E Thies, E Mandelkow, EM Mandelkow
Journal of Neuroscience 30 (36), 11938-11950, 2010
8282010
Domains of tau protein and interactions with microtubules
N Gustke, B Trinczek, J Biernat, EM Mandelkow, E Mandelkow
Biochemistry 33 (32), 9511-9522, 1994
8121994
Tau in Alzheimer's disease
EM Mandelkow, E Mandelkow
Trends in cell biology 8 (11), 425-427, 1998
7761998
Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer‐like state.
G Drewes, B Lichtenberg‐Kraag, F Döring, EM Mandelkow, J Biernat, ...
The EMBO journal 11 (6), 2131-2138, 1992
7711992
Microtubule dynamics and microtubule caps: a time-resolved cryo-electron microscopy study.
EM Mandelkow, E Mandelkow, RA Milligan
The Journal of cell biology 114 (5), 977-991, 1991
7511991
Glycogen synthase kinase‐3 and the Alzheimer‐like state of microtubule‐associated protein tau
EM Mandelkow, G Drewes, J Biernat, N Gustke, J Van Lint, ...
FEBS letters 314 (3), 315-321, 1992
7241992
Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing
Y Wang, M Martinez-Vicente, U Krüger, S Kaushik, E Wong, ...
Human molecular genetics 18 (21), 4153-4170, 2009
7012009
The release and trans-synaptic transmission of Tau via exosomes
Y Wang, V Balaji, S Kaniyappan, L Krüger, S Irsen, K Tepper, ...
Molecular neurodegeneration 12, 1-25, 2017
6952017
Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local β-structure
M Von Bergen, S Barghorn, L Li, A Marx, J Biernat, EM Mandelkow, ...
Journal of Biological Chemistry 276 (51), 48165-48174, 2001
6902001
Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments
A Schneider, J Biernat, M Von Bergen, E Mandelkow, EM Mandelkow
Biochemistry 38 (12), 3549-3558, 1999
6771999
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