Abdominal FLASH irradiation reduces radiation-induced gastrointestinal toxicity for the treatment of ovarian cancer in mice K Levy, S Natarajan, J Wang, S Chow, JT Eggold, PE Loo, R Manjappa, ... Scientific reports 10 (1), 21600, 2020 | 157 | 2020 |
FLASH irradiation results in reduced severe skin toxicity compared to conventional-dose-rate irradiation LA Soto, KM Casey, J Wang, A Blaney, R Manjappa, D Breitkreutz, ... Radiation research 194 (6), 618-624, 2020 | 85 | 2020 |
Metabolic profiling reveals a dependency of human metastatic breast cancer on mitochondrial serine and one-carbon unit metabolism AM Li, GS Ducker, Y Li, JA Seoane, Y Xiao, S Melemenidis, Y Zhou, L Liu, ... Molecular Cancer Research 18 (4), 599-611, 2022 | 71 | 2022 |
Molecular magnetic resonance imaging of angiogenesis in vivo using polyvalent cyclic RGD-iron oxide microparticle conjugates S Melemenidis, A Jefferson, N Ruparelia, AM Akhtar, J Xie, D Allen, ... Theranostics 5 (5), 515, 2015 | 58 | 2015 |
Abdominopelvic FLASH irradiation improves PD-1 immune checkpoint inhibition in preclinical models of ovarian cancer JT Eggold, S Chow, S Melemenidis, J Wang, S Natarajan, PE Loo, ... Molecular cancer therapeutics 21 (2), 371-381, 2022 | 43 | 2022 |
Macrophages promote circulating tumor cell–mediated local recurrence following radiotherapy in immunosuppressed patients M Rafat, TA Aguilera, M Vilalta, LL Bronsart, LA Soto, R Von Eyben, ... Cancer research 78 (15), 4241-4252, 2018 | 43 | 2018 |
Multicellular spheroids as in vitro models of oxygen depletion during FLASH irradiation S Khan, M Bassenne, J Wang, R Manjappa, S Melemenidis, ... International Journal of Radiation Oncology* Biology* Physics 110 (3), 833-844, 2021 | 35 | 2021 |
Theranostic nanoparticles enhance the response of glioblastomas to radiation W Wu, JL Klockow, S Mohanty, KS Ku, M Aghighi, S Melemenidis, Z Chen, ... Nanotheranostics 3 (4), 299, 2019 | 18 | 2019 |
The tumour microenvironment links complement system dysregulation and hypoxic signalling MM Olcina, RK Kim, S Melemenidis, EE Graves, AJ Giaccia The British journal of radiology 92 (1093), 20180069, 2018 | 15 | 2018 |
Design and validation of a dosimetric comparison scheme tailored for ultra-high dose-rate electron beams to support multicenter FLASH preclinical studies PG Jorge, S Melemenidis, V Grilj, T Buchillier, R Manjappa, ... Radiotherapy and Oncology 175, 203-209, 2022 | 11 | 2022 |
Endogenous retroviral elements generate pathologic neutrophils in pulmonary arterial hypertension S Taylor, S Isobe, A Cao, K Contrepois, BA Benayoun, L Jiang, L Wang, ... American journal of respiratory and critical care medicine 206 (8), 1019-1034, 2022 | 10 | 2022 |
Molecular Magnetic Resonance Imaging of Angiogenesis S Melemenidis, A Jefferson, N Ruparelia, AM Akhtar, J Xie, D Allen, ... Vivo, 0 | 6 | |
Real-time optical oximetry during FLASH radiotherapy using a phosphorescent nanoprobe B Ha, K Liang, C Liu, S Melemenidis, R Manjappa, V Viswanathan, N Das, ... Radiotherapy and Oncology 176, 239-243, 2022 | 5 | 2022 |
Increased local tumor control through nanoparticle-mediated, radiation-triggered release of nitrite, an important precursor for reactive nitrogen species AS Kim, S Melemenidis, AK Gustavsson, D Abid, Y Wu, F Liu, D Hristov, ... Physics in Medicine & Biology 65 (19), 195003, 2020 | 5 | 2020 |
FLASH-RT does not affect chromosome translocations and junction structures beyond that of CONV-RT dose-rates PG Barghouth, S Melemenidis, P Montay-Gruel, J Ollivier, V Viswanathan, ... Radiotherapy and Oncology 188, 109906, 2023 | 3 | 2023 |
Evaluating the reproducibility of mouse anatomy under rotation in a custom immobilization device for conformal FLASH radiotherapy RB Ko, LA Soto, R von Eyben, S Melemenidis, EB Rankin, PG Maxim, ... Radiation research 194 (6), 600-606, 2020 | 3 | 2020 |
Clinical linear accelerator-based electron FLASH: pathway for practical translation to FLASH clinical trials HJ No, YF Wu, ML Dworkin, R Manjappa, L Skinner, MR Ashraf, B Lau, ... International Journal of Radiation Oncology* Biology* Physics 117 (2), 482-492, 2023 | 2 | 2023 |
Clinical LINAC-Based Electron FLASH: Pathway for Practical Translation to Trials of FLASH Radiotherapy HJ No, YF Wu, ML Dworkin, R Ashraf, R Manjappa, L Skinner, B Lau, ... International Journal of Radiation Oncology, Biology, Physics 114 (3), e539, 2022 | 2 | 2022 |
Feasibility of clinically practical ultra-high dose rate (FLASH) radiation delivery by a reversible configuration of a standard clinical-use linear accelerator HJ No, YF Wu, R Manjappa, L Skinner, B Lau, S Melemenidis, SJ Yu, ... International journal of radiation oncology, biology, physics 111 (3), S32, 2021 | 2 | 2021 |
Endogenous retroviral elements generate pathologic neutrophils and elastase rich exosomes in pulmonary arterial hypertension S Taylor, K Contrepois, BA Benayoun, L Jiang, S Isobe, L Wang, ... bioRxiv, 2021.01. 08.426001, 2021 | 2 | 2021 |