Eric A Sobie
Eric A Sobie
Mount Sinai
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Cited by
Cited by
Orphaned ryanodine receptors in the failing heart
LS Song, EA Sobie, S McCulle, WJ Lederer, CW Balke, H Cheng
Proceedings of the National Academy of Sciences 103 (11), 4305-4310, 2006
The library of integrated network-based cellular signatures NIH program: system-level cataloging of human cells response to perturbations
AB Keenan, SL Jenkins, KM Jagodnik, S Koplev, E He, D Torre, Z Wang, ...
Cell systems 6 (1), 13-24, 2018
Termination of cardiac Ca2+ sparks: an investigative mathematical model of calcium-induced calcium release
EA Sobie, KW Dilly, J dos Santos Cruz, WJ Lederer, MS Jafri
Biophysical journal 83 (1), 59-78, 2002
Parameter sensitivity analysis in electrophysiological models using multivariable regression
EA Sobie
Biophysical journal 96 (4), 1264-1274, 2009
A generalized activating function for predicting virtual electrodes in cardiac tissue
EA Sobie, RC Susil, L Tung
Biophysical journal 73 (3), 1410-1423, 1997
Exploiting mathematical models to illuminate electrophysiological variability between individuals
AX Sarkar, DJ Christini, EA Sobie
The Journal of physiology 590 (11), 2555-2567, 2012
Regression analysis for constraining free parameters in electrophysiological models of cardiac cells
AX Sarkar, EA Sobie
PLoS computational biology 6 (9), e1000914, 2010
The Ca2+ leak paradox and “rogue ryanodine receptors”: SR Ca2+ efflux theory and practice
EA Sobie, S Guatimosim, L Gómez-Viquez, LS Song, H Hartmann, ...
Progress in biophysics and molecular biology 90 (1-3), 172-185, 2006
Local Ca2+ signaling and EC coupling in heart: Ca2+ sparks and the regulation of the [Ca2+] i transient
S Guatimosim, K Dilly, LF Santana, MS Jafri, EA Sobie, WJ Lederer
Journal of molecular and cellular cardiology 34 (8), 941-950, 2002
Dynamics of calcium sparks and calcium leak in the heart
GSB Williams, AC Chikando, HTM Tuan, EA Sobie, WJ Lederer, MS Jafri
Biophysical journal 101 (6), 1287-1296, 2011
Nonuniform responses of transmembrane potential during electric field stimulation of single cardiac cells
DKL Cheng, L Tung, EA Sobie
American Journal of Physiology-Heart and Circulatory Physiology 277 (1 …, 1999
Improved prediction of drug‐induced Torsades de Pointes through simulations of dynamics and machine learning algorithms
MC Lancaster, EA Sobie
Clinical Pharmacology & Therapeutics 100 (4), 371-379, 2016
A multi-center study on the reproducibility of drug-response assays in mammalian cell lines
M Niepel, M Hafner, CE Mills, K Subramanian, EH Williams, M Chung, ...
Cell systems 9 (1), 35-48. e5, 2019
Quantification of repolarization reserve to understand interpatient variability in the response to proarrhythmic drugs: a computational analysis
AX Sarkar, EA Sobie
Heart Rhythm 8 (11), 1749-1755, 2011
Local recovery of Ca2+ release in rat ventricular myocytes
EA Sobie, LS Song, WJ Lederer
The Journal of physiology 565 (2), 441-447, 2005
Recovery of cardiac calcium release is controlled by sarcoplasmic reticulum refilling and ryanodine receptor sensitivity
HR Ramay, OZ Liu, EA Sobie
Cardiovascular research 91 (4), 598-605, 2011
Mathematical model of the neonatal mouse ventricular action potential
LJ Wang, EA Sobie
American Journal of Physiology-Heart and Circulatory Physiology 294 (6 …, 2008
Calcium biology of the transverse tubules in heart
LS SONG, S Guatimosim, L GÓMEZ‐VIQUEZ, EA Sobie, A Ziman, ...
Annals of the New York Academy of Sciences 1047 (1), 99-111, 2005
Stretch-induced changes in arrhythmogenesis and excitability in experimentally based heart cell models
TL Riemer, EA Sobie, L Tung
American Journal of Physiology-Heart and Circulatory Physiology 275 (2 …, 1998
Molecular identification of a TTX-sensitive Ca2+ current
S Guatimosim, EA Sobie, J dos Santos Cruz, LA Martin, WJ Lederer
American Journal of Physiology-Cell Physiology 280 (5), C1327-C1339, 2001
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