| Orphaned ryanodine receptors in the failing heart LS Song, EA Sobie, S McCulle, WJ Lederer, CW Balke, H Cheng Proceedings of the National Academy of Sciences 103 (11), 4305-4310, 2006 | 502 | 2006 |
| The library of integrated network-based cellular signatures NIH program: system-level cataloging of human cells response to perturbations AB Keenan, SL Jenkins, KM Jagodnik, S Koplev, E He, D Torre, Z Wang, ... Cell systems 6 (1), 13-24, 2018 | 400 | 2018 |
| Termination of cardiac Ca2+ sparks: an investigative mathematical model of calcium-induced calcium release EA Sobie, KW Dilly, J dos Santos Cruz, WJ Lederer, MS Jafri Biophysical journal 83 (1), 59-78, 2002 | 342 | 2002 |
| Parameter sensitivity analysis in electrophysiological models using multivariable regression EA Sobie Biophysical journal 96 (4), 1264-1274, 2009 | 279 | 2009 |
| A generalized activating function for predicting virtual electrodes in cardiac tissue EA Sobie, RC Susil, L Tung Biophysical journal 73 (3), 1410-1423, 1997 | 192 | 1997 |
| Exploiting mathematical models to illuminate electrophysiological variability between individuals AX Sarkar, DJ Christini, EA Sobie The Journal of physiology 590 (11), 2555-2567, 2012 | 165 | 2012 |
| Regression analysis for constraining free parameters in electrophysiological models of cardiac cells AX Sarkar, EA Sobie PLoS computational biology 6 (9), e1000914, 2010 | 154 | 2010 |
| The Ca2+ leak paradox and “rogue ryanodine receptors”: SR Ca2+ efflux theory and practice EA Sobie, S Guatimosim, L Gómez-Viquez, LS Song, H Hartmann, ... Progress in biophysics and molecular biology 90 (1-3), 172-185, 2006 | 149 | 2006 |
| Local Ca2+ signaling and EC coupling in heart: Ca2+ sparks and the regulation of the [Ca2+] i transient S Guatimosim, K Dilly, LF Santana, MS Jafri, EA Sobie, WJ Lederer Journal of molecular and cellular cardiology 34 (8), 941-950, 2002 | 147 | 2002 |
| Dynamics of calcium sparks and calcium leak in the heart GSB Williams, AC Chikando, HTM Tuan, EA Sobie, WJ Lederer, MS Jafri Biophysical journal 101 (6), 1287-1296, 2011 | 145 | 2011 |
| Nonuniform responses of transmembrane potential during electric field stimulation of single cardiac cells DKL Cheng, L Tung, EA Sobie American Journal of Physiology-Heart and Circulatory Physiology 277 (1 …, 1999 | 144 | 1999 |
| Improved prediction of drug‐induced Torsades de Pointes through simulations of dynamics and machine learning algorithms MC Lancaster, EA Sobie Clinical Pharmacology & Therapeutics 100 (4), 371-379, 2016 | 130 | 2016 |
| A multi-center study on the reproducibility of drug-response assays in mammalian cell lines M Niepel, M Hafner, CE Mills, K Subramanian, EH Williams, M Chung, ... Cell systems 9 (1), 35-48. e5, 2019 | 124 | 2019 |
| Quantification of repolarization reserve to understand interpatient variability in the response to proarrhythmic drugs: a computational analysis AX Sarkar, EA Sobie Heart Rhythm 8 (11), 1749-1755, 2011 | 120 | 2011 |
| Local recovery of Ca2+ release in rat ventricular myocytes EA Sobie, LS Song, WJ Lederer The Journal of physiology 565 (2), 441-447, 2005 | 103 | 2005 |
| Recovery of cardiac calcium release is controlled by sarcoplasmic reticulum refilling and ryanodine receptor sensitivity HR Ramay, OZ Liu, EA Sobie Cardiovascular research 91 (4), 598-605, 2011 | 101 | 2011 |
| Mathematical model of the neonatal mouse ventricular action potential LJ Wang, EA Sobie American Journal of Physiology-Heart and Circulatory Physiology 294 (6 …, 2008 | 91 | 2008 |
| Calcium biology of the transverse tubules in heart LS SONG, S Guatimosim, L GÓMEZ‐VIQUEZ, EA Sobie, A Ziman, ... Annals of the New York Academy of Sciences 1047 (1), 99-111, 2005 | 91 | 2005 |
| Stretch-induced changes in arrhythmogenesis and excitability in experimentally based heart cell models TL Riemer, EA Sobie, L Tung American Journal of Physiology-Heart and Circulatory Physiology 275 (2 …, 1998 | 90 | 1998 |
| Na+ channel function, regulation, structure, trafficking and sequestration Y Chen‐Izu, RM Shaw, GS Pitt, V Yarov‐Yarovoy, JT Sack, H Abriel, ... The Journal of physiology 593 (6), 1347-1360, 2015 | 88 | 2015 |
W. J. LedererUniversity of MarylandVerified email at som.umaryland.edu
