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Centre for Genomic Regulation
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Year
An experimental assay of the interactions of amino acids from orthologous sequences shaping a complex fitness landscape
VO Pokusaeva, DR Usmanova, EV Putintseva, L Espinar, KS Sarkisyan, ...
PLoS genetics 15 (4), e1008079, 2019
982019
Temporal competition between differentiation programs determines cell fate choice
A Kuchina, L Espinar, T Çağatay, AO Balbin, F Zhang, A Alvarado, ...
Molecular systems biology 7 (1), 557, 2011
922011
Uncovering de novo gene birth in yeast using deep transcriptomics
WR Blevins, J Ruiz-Orera, X Messeguer, B Blasco-Moreno, ...
Nature communications 12 (1), 604, 2021
732021
Slow-growing cells within isogenic populations have increased RNA polymerase error rates and DNA damage
D Van Dijk, R Dhar, AM Missarova, L Espinar, WR Blevins, B Lehner, ...
Nature communications 6 (1), 7972, 2015
552015
Reversible and noisy progression towards a commitment point enables adaptable and reliable cellular decision-making
A Kuchina, L Espinar, J Garcia-Ojalvo, GM Süel
PLoS computational biology 7 (11), e1002273, 2011
492011
Circuit-level input integration in bacterial gene regulation
L Espinar, M Dies, T Çağatay, GM Süel, J Garcia-Ojalvo
Proceedings of the National Academy of Sciences 110 (17), 7091-7096, 2013
312013
Promoter architecture determines cotranslational regulation of mRNA
L Espinar, MÀS Tamarit, J Domingo, LB Carey
Genome research 28 (4), 509-518, 2018
242018
A synthetic gene circuit for measuring autoregulatory feedback control
MÀ Schikora-Tamarit, C Toscano-Ochoa, J Domingo Espinós, L Espinar, ...
Integrative Biology 8 (4), 546-555, 2016
92016
Experimental assay of a fitness landscape on a macroevolutionary scale
VO Pokusaeva, DR Usmanova, EV Putintseva, L Espinar, KS Sarkisyan, ...
bioRxiv, 222778, 2017
72017
Strand asymmetry influences mismatch resolution during single-strand annealing
VO Pokusaeva, AR Diez, L Espinar, AT Pérez, GJ Filion
Genome Biology 23 (1), 93, 2022
6*2022
Frequent birth of de novo genes in the compact yeast genome
WR Blevins, J Ruiz-Orera, X Messeguer, B Blasco-Moreno, ...
bioRxiv, 575837, 2019
62019
Interactions between BRD4S, LOXL2, and MED1 drive cell cycle transcription in triple‐negative breast cancer
L Pascual‐Reguant, Q Serra‐Camprubí, D Datta, D Cianferoni, S Kourtis, ...
EMBO Molecular Medicine 15 (12), e18459, 2023
22023
Nuclear MTHFD2 secures mitosis progression by preserving centromere integrity
N Pardo-Lorente, A Gkanogiannis, L Cozzuto, AG Zapater, L Espinar, ...
bioRxiv, 2023.06. 01.543193, 2023
12023
Mitochondria-derived nuclear ATP surge protects against confinement-induced proliferation defects
R Ghose, F Pezzano, S Kourtis, I Sheraj, S Das, A Ganez-Zapater, ...
bioRxiv, 2023.12. 20.572417, 2023
2023
Adaptation to ARF6-depletion in KRAS-driven PDAC is abolished by targeting TLR2
R Ghose, S Das, J Urgel-Solas, F Pezzano, D Datta, U Ghose, ...
bioRxiv, 2023.11. 30.569405, 2023
2023
Interactions between BRD4 short, LOXL2, and MED1 drive cell cycle transcription in triple-negative breast cancer
LP Reguant, TV Tian, D Datta, D Cianferoni, S Kourtis, A Gañez-Zapater, ...
European Journal of Cancer 174, S61-S62, 2022
2022
The BRD4S-LOXL2-MED1 interaction at the forefront of cell cycle transcriptional control in triple-negative breast cancer
L Pascual-Reguant, TV Tian, D Datta, D Cianferoni, S Kourtis, ...
bioRxiv, 2022.05. 27.493725, 2022
2022
Frequent birth ofde novogenes in the compact yeast genome
WR Blevins, J Ruiz-Orera, X Messeguer, B Blasco-Moreno, ...
2019
A synthetic gene circuit for measuring autoregulatory feedback control
C Toscano-Ochoa, JD Espinós, L Espinar, LB Carey
2016
Reversible and Noisy Progression towards a Commitment Point Enables Adaptable and Reliable
A Kuchina, L Espinar, J Garcia-Ojalvo, GM Süel
2011
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Articles 1–20