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Ramsey Majzoub
Ramsey Majzoub
Postdoctoral Fellow, Janssen BioTherapeutics
Verified email at its.jnj.com
Title
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Cited by
Year
Endosomal escape and transfection efficiency of PEGylated cationic liposome–DNA complexes prepared with an acid-labile PEG-lipid
CL Chan, RN Majzoub, RS Shirazi, KK Ewert, YJ Chen, KS Liang, ...
Biomaterials 33 (19), 4928-4935, 2012
1622012
Cationic liposome–nucleic acid complexes for gene delivery and gene silencing
CR Safinya, KK Ewert, RN Majzoub, C Leal
New Journal of Chemistry 38 (11), 5164-5172, 2014
1092014
Synthesis and characterization of degradable multivalent cationic lipids with disulfide-bond spacers for gene delivery
RS Shirazi, KK Ewert, C Leal, RN Majzoub, NF Bouxsein, CR Safinya
Biochimica et Biophysica Acta (BBA)-Biomembranes 1808 (9), 2156-2166, 2011
972011
Uptake and transfection efficiency of PEGylated cationic liposome–DNA complexes with and without RGD-tagging
RN Majzoub, CL Chan, KK Ewert, BFB Silva, KS Liang, EL Jacovetty, ...
Biomaterials 35 (18), 4996-5005, 2014
922014
Cationic liposome–nucleic acid nanoparticle assemblies with applications in gene delivery and gene silencing
RN Majzoub, KK Ewert, CR Safinya
Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2016
872016
Competition of charge-mediated and specific binding by peptide-tagged cationic liposome–DNA nanoparticles in vitro and in vivo
E Wonder, L Simón-Gracia, P Scodeller, RN Majzoub, VR Kotamraju, ...
Biomaterials 166, 52-63, 2018
752018
Optimizing cationic and neutral lipids for efficient gene delivery at high serum content
CL Chan, KK Ewert, RN Majzoub, YK Hwu, KS Liang, C Leal, CR Safinya
The journal of gene medicine 16 (3-4), 84-96, 2014
622014
Synthesis of linear and cyclic peptide–PEG–lipids for stabilization and targeting of cationic liposome–DNA complexes
KK Ewert, VR Kotamraju, RN Majzoub, VM Steffes, EA Wonder, T Teesalu, ...
Bioorganic & medicinal chemistry letters 26 (6), 1618-1623, 2016
492016
PEGylated cationic liposome–DNA complexation in brine is pathway-dependent
BFB Silva, RN Majzoub, CL Chan, Y Li, U Olsson, CR Safinya
Biochimica et Biophysica Acta (BBA)-Biomembranes 1838 (1), 398-412, 2014
392014
Fluorescence microscopy colocalization of lipid–nucleic acid nanoparticles with wildtype and mutant Rab5–GFP: A platform for investigating early endosomal events
RN Majzoub, CL Chan, KK Ewert, BFB Silva, KS Liang, CR Safinya
Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (6), 1308-1318, 2015
372015
Rab11 and lysotracker markers reveal correlation between endosomal pathways and transfection efficiency of surface-functionalized cationic liposome–DNA nanoparticles
RN Majzoub, E Wonder, KK Ewert, VR Kotamraju, T Teesalu, CR Safinya
The Journal of Physical Chemistry B 120 (26), 6439-6453, 2016
282016
Patterned threadlike micelles and DNA-tethered nanoparticles: a structural study of PEGylated cationic liposome–DNA assemblies
RN Majzoub, KK Ewert, EL Jacovetty, B Carragher, CS Potter, Y Li, ...
Langmuir 31 (25), 7073-7083, 2015
242015
CRISPR/Cas9-mediated targeted insertion of human F9 achieves therapeutic circulating protein levels in mice and non-human primates
HR Huang, C Moroski-Erkul, P Bialek, C Wang, G Gong, S Hartfort, ...
Mol. Ther 27 (4 Suppl 1), 7, 2019
172019
Quantitative Intracellular Localization of Cationic Lipid–Nucleic Acid Nanoparticles with Fluorescence Microscopy
RN Majzoub, KK Ewert, CR Safinya
Non-viral gene delivery vectors: methods and protocols, 77-108, 2016
122016
Assembly of Building Blocks by Double-End-Anchored Polymers in the Dilute Regime Mediated by Hydrophobic Interactions at Controlled Distances
EA Wonder, KK Ewert, C Liu, VM Steffes, J Kwak, V Qahar, RN Majzoub, ...
ACS applied materials & interfaces 12 (41), 45728-45743, 2020
42020
Investigating Intracellular Pathways of Surface-Functionalized Cationic Lipid-DNA Nanoparticles using Quantitative Fluorescence Microscopy
RN Majzoub
University of California, Santa Barbara, 2015
22015
pH-Sensitive pegylated cationic lipid-DNA complexes for gene delivery: transfection efficiency and live cell imaging studies
CL Chan, R Majzoub, RS Shirazi, KS Liang, KK Ewert, CR Safinya
Biophysical Journal 102 (3), 501a-502a, 2012
12012
CRISPR-Mediated Insertion of a Targeted GAA Transgene into Hepatocytes Provides Effective, Long-Lasting Gene Therapy in Neonate and Adult Pompe Disease Mice
AD Baik, P Calafati, LR Sabin, S Moller-Tank, A Forget, HR Huang, ...
MOLECULAR THERAPY 30 (4), 43-43, 2022
2022
Enhanced tgTCR T Cell Product Attributes Through Process Improvement of CRISPR/Cas9 Engineering
A Prodeus, P Narenda, I Dutta, S Yazinksi, R Majzoub, C Blanchard, ...
MOLECULAR THERAPY 28 (4), 17-18, 2020
2020
Studying intracellular pathways of cationic liposome-nucleic acid nanoparticle assemblies with applications in gene delivery
K Ewert, R Majzoub, E Wonder, V Steffes, C Safinya
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016
2016
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