Endosomal escape and transfection efficiency of PEGylated cationic liposome–DNA complexes prepared with an acid-labile PEG-lipid CL Chan, RN Majzoub, RS Shirazi, KK Ewert, YJ Chen, KS Liang, ... Biomaterials 33 (19), 4928-4935, 2012 | 169 | 2012 |
Cationic liposome–nucleic acid complexes for gene delivery and gene silencing CR Safinya, KK Ewert, RN Majzoub, C Leal New Journal of Chemistry 38 (11), 5164-5172, 2014 | 111 | 2014 |
Synthesis and characterization of degradable multivalent cationic lipids with disulfide-bond spacers for gene delivery RS Shirazi, KK Ewert, C Leal, RN Majzoub, NF Bouxsein, CR Safinya Biochimica et Biophysica Acta (BBA)-Biomembranes 1808 (9), 2156-2166, 2011 | 98 | 2011 |
Uptake and transfection efficiency of PEGylated cationic liposome–DNA complexes with and without RGD-tagging RN Majzoub, CL Chan, KK Ewert, BFB Silva, KS Liang, EL Jacovetty, ... Biomaterials 35 (18), 4996-5005, 2014 | 95 | 2014 |
Cationic liposome–nucleic acid nanoparticle assemblies with applications in gene delivery and gene silencing RN Majzoub, KK Ewert, CR Safinya Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2016 | 93 | 2016 |
Competition of charge-mediated and specific binding by peptide-tagged cationic liposome–DNA nanoparticles in vitro and in vivo E Wonder, L Simón-Gracia, P Scodeller, RN Majzoub, VR Kotamraju, ... Biomaterials 166, 52-63, 2018 | 78 | 2018 |
Optimizing cationic and neutral lipids for efficient gene delivery at high serum content CL Chan, KK Ewert, RN Majzoub, YK Hwu, KS Liang, C Leal, CR Safinya The journal of gene medicine 16 (3-4), 84-96, 2014 | 65 | 2014 |
Synthesis of linear and cyclic peptide–PEG–lipids for stabilization and targeting of cationic liposome–DNA complexes KK Ewert, VR Kotamraju, RN Majzoub, VM Steffes, EA Wonder, T Teesalu, ... Bioorganic & medicinal chemistry letters 26 (6), 1618-1623, 2016 | 50 | 2016 |
PEGylated cationic liposome–DNA complexation in brine is pathway-dependent BFB Silva, RN Majzoub, CL Chan, Y Li, U Olsson, CR Safinya Biochimica et Biophysica Acta (BBA)-Biomembranes 1838 (1), 398-412, 2014 | 40 | 2014 |
Fluorescence microscopy colocalization of lipid–nucleic acid nanoparticles with wildtype and mutant Rab5–GFP: A platform for investigating early endosomal events RN Majzoub, CL Chan, KK Ewert, BFB Silva, KS Liang, CR Safinya Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (6), 1308-1318, 2015 | 39 | 2015 |
Rab11 and lysotracker markers reveal correlation between endosomal pathways and transfection efficiency of surface-functionalized cationic liposome–DNA nanoparticles RN Majzoub, E Wonder, KK Ewert, VR Kotamraju, T Teesalu, CR Safinya The Journal of Physical Chemistry B 120 (26), 6439-6453, 2016 | 29 | 2016 |
Patterned threadlike micelles and DNA-tethered nanoparticles: a structural study of PEGylated cationic liposome–DNA assemblies RN Majzoub, KK Ewert, EL Jacovetty, B Carragher, CS Potter, Y Li, ... Langmuir 31 (25), 7073-7083, 2015 | 27 | 2015 |
CRISPR/Cas9-mediated targeted insertion of human F9 achieves therapeutic circulating protein levels in mice and non-human primates HR Huang, C Moroski-Erkul, P Bialek, C Wang, G Gong, S Hartfort, ... Mol. Ther 27 (4 Suppl 1), 7, 2019 | 18 | 2019 |
Quantitative Intracellular Localization of Cationic Lipid–Nucleic Acid Nanoparticles with Fluorescence Microscopy RN Majzoub, KK Ewert, CR Safinya Non-viral gene delivery vectors: methods and protocols, 77-108, 2016 | 12 | 2016 |
Assembly of Building Blocks by Double-End-Anchored Polymers in the Dilute Regime Mediated by Hydrophobic Interactions at Controlled Distances EA Wonder, KK Ewert, C Liu, VM Steffes, J Kwak, V Qahar, RN Majzoub, ... ACS applied materials & interfaces 12 (41), 45728-45743, 2020 | 5 | 2020 |
Investigating Intracellular Pathways of Surface-Functionalized Cationic Lipid-DNA Nanoparticles using Quantitative Fluorescence Microscopy RN Majzoub University of California, Santa Barbara, 2015 | 2 | 2015 |
Supra-therapeutic levels of transgene expression achieved in vivo by CRISPR/Cas9 mediated targeted gene insertion HR Huang, J Xie, C Moroski-Erkul, C Wang, G Gong, S Hartfort, R Sattler, ... HUMAN GENE THERAPY 29 (12), A26-A26, 2018 | 1 | 2018 |
pH-Sensitive pegylated cationic lipid-DNA complexes for gene delivery: transfection efficiency and live cell imaging studies CL Chan, R Majzoub, RS Shirazi, KS Liang, KK Ewert, CR Safinya Biophysical Journal 102 (3), 501a-502a, 2012 | 1 | 2012 |
CRISPR-Mediated Insertion of a Targeted GAA Transgene into Hepatocytes Provides Effective, Long-Lasting Gene Therapy in Neonate and Adult Pompe Disease Mice AD Baik, P Calafati, LR Sabin, S Moller-Tank, A Forget, HR Huang, ... MOLECULAR THERAPY 30 (4), 43-43, 2022 | | 2022 |
Enhanced tgTCR T Cell Product Attributes Through Process Improvement of CRISPR/Cas9 Engineering A Prodeus, P Narenda, I Dutta, S Yazinksi, R Majzoub, C Blanchard, ... MOLECULAR THERAPY 28 (4), 17-18, 2020 | | 2020 |