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Carsten Saft
Carsten Saft
Professor of Neurology
Verified email at rub.de
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Year
Targeting huntingtin expression in patients with Huntington’s disease
SJ Tabrizi, BR Leavitt, GB Landwehrmeyer, EJ Wild, C Saft, RA Barker, ...
New England Journal of Medicine 380 (24), 2307-2316, 2019
6602019
Topography of cerebral atrophy in early Huntington’s disease: a voxel based morphometric MRI study
J Kassubek, FD Juengling, T Kioschies, K Henkel, J Karitzky, B Kramer, ...
Journal of Neurology, Neurosurgery & Psychiatry 75 (2), 213-220, 2004
3282004
Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study
DJH Moss, AF Pardiñas, D Langbehn, K Lo, BR Leavitt, R Roos, A Durr, ...
The Lancet Neurology 16 (9), 701-711, 2017
3082017
Response inhibition subprocesses and dopaminergic pathways: basal ganglia disease effects
C Beste, R Willemssen, C Saft, M Falkenstein
Neuropsychologia 48 (2), 366-373, 2010
2372010
Mitochondrial impairment in patients and asymptomatic mutation carriers of Huntington's disease
C Saft, J Zange, J Andrich, K Müller, K Lindenberg, B Landwehrmeyer, ...
Movement disorders: official journal of the Movement Disorder Society 20 (6 …, 2005
2252005
Pridopidine for the treatment of motor function in patients with Huntington's disease (MermaiHD): a phase 3, randomised, double-blind, placebo-controlled trial
JG de Yebenes, B Landwehrmeyer, F Squitieri, R Reilmann, A Rosser, ...
The Lancet Neurology 10 (12), 1049-1057, 2011
1962011
Efficacy of fumaric acid esters in the R6/2 and YAC128 models of Huntington's disease
G Ellrichmann, E Petrasch-Parwez, DH Lee, C Reick, L Arning, C Saft, ...
PloS one 6 (1), e16172, 2011
1922011
Treating the whole body in Huntington's disease
JB Carroll, GP Bates, J Steffan, C Saft, SJ Tabrizi
The Lancet Neurology 14 (11), 1135-1142, 2015
1822015
The role of the immune system in Huntington’s disease
G Ellrichmann, C Reick, C Saft, RA Linker
Journal of Immunology Research 2013 (1), 541259, 2013
1682013
An exploratory double‐blind, randomized clinical trial with selisistat, a SirT1 inhibitor, in patients with H untington's disease
SD Süssmuth, S Haider, GB Landwehrmeyer, R Farmer, C Frost, ...
British journal of clinical pharmacology 79 (3), 465-476, 2015
1642015
PGC-1alphaas modifier of onset age in Huntington disease
E Taherzadeh-Fard, C Saft, J Andrich, S Wieczorek, L Arning
Molecular neurodegeneration 4, 1-4, 2009
1362009
PGC-1alpha downstream transcription factors NRF-1 and TFAM are genetic modifiers of Huntington disease
E Taherzadeh-Fard, C Saft, DA Akkad, S Wieczorek, A Haghikia, A Chan, ...
Molecular neurodegeneration 6, 1-8, 2011
1332011
Autonomic nervous system function in Huntington's disease
J Andrich, T Schmitz, C Saft, T Postert, P Kraus, JT Epplen, H Przuntek, ...
Journal of Neurology, Neurosurgery & Psychiatry 72 (6), 726-731, 2002
1332002
NR2A and NR2B receptor gene variations modify age at onset in Huntington disease
L Arning, PH Kraus, S Valentin, C Saft, J Andrich, JT Epplen
Neurogenetics 6, 25-28, 2005
1252005
Severe ultrastructural mitochondrial changes in lymphoblasts homozygous for Huntington disease mutation
F Squitieri, M Cannella, G Sgarbi, V Maglione, A Falleni, P Lenzi, ...
Mechanisms of ageing and development 127 (2), 217-220, 2006
1232006
Response inhibition in Huntington's disease—a study using ERPs and sLORETA
C Beste, C Saft, J Andrich, R Gold, M Falkenstein
Neuropsychologia 46 (5), 1290-1297, 2008
1212008
Mechanisms mediating parallel action monitoring in fronto-striatal circuits
C Beste, V Ness, C Lukas, R Hoffmann, S Stüwe, M Falkenstein, C Saft
Neuroimage 62 (1), 137-146, 2012
1062012
Patterns of CAG repeat instability in the central nervous system and periphery in Huntington’s disease and in spinocerebellar ataxia type 1
R Mouro Pinto, L Arning, JV Giordano, P Razghandi, MA Andrew, T Gillis, ...
Human molecular genetics 29 (15), 2551-2567, 2020
992020
Safety and efficacy of pridopidine in patients with Huntington's disease (PRIDE-HD): a phase 2, randomised, placebo-controlled, multicentre, dose-ranging study
R Reilmann, A McGarry, ID Grachev, JM Savola, B Borowsky, E Eyal, ...
The Lancet Neurology 18 (2), 165-176, 2019
962019
Chorein‐sensitive polymerization of cortical actin and suicidal cell death in chorea‐acanthocytosis
M Föller, A Hermann, S Gu, I Alesutan, SM Qadri, O Borst, EM Schmidt, ...
The FASEB Journal 26 (4), 1526-1534, 2012
922012
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